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- ALBERGO, S, et al.
(författare)
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LIGHT-PULSES TO PHOTOMULTIPLIER TUBES FROM EXTENDED SCINTILLATORS
- 1995
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Ingår i: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. - : ELSEVIER SCIENCE BV. ; 362:2-3, s. 423-433
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Light pulses seen by photomultiplier tubes (PMTs) after propagation within long scintillator slats or rods, or large disc-shaped scintillators are investigated and compared with those from point-like scintillators. Results of experimental tests for the di
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- Isgro, MA, et al.
(författare)
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Immunotherapy may protect cancer patients from SARS-CoV-2 infection: a single-center retrospective analysis
- 2021
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Ingår i: Journal of translational medicine. - : Springer Science and Business Media LLC. - 1479-5876. ; 19:1, s. 132-
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Tidskriftsartikel (refereegranskat)abstract
- Coronavirus disease 2019 (COVID-19) global pandemic has created unique challenges to healthcare systems throughout the world. Ensuring subjects’ safety is mandatory especially in oncology, in consideration of cancer patients’ particular frailty. We examined the proportion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgM and/or IgG positive subjects in three different groups from Istituto Nazionale Tumori – IRCCS “Fondazione G. Pascale” in Naples (Campania region, Italy): cancer patients treated with Innovative Immunotherapy (Immune Checkpoint Inhibitors, ICIs), cancer patients undergoing standard Chemotherapies (CHTs) and healthcare providers. 9 out of 287 (3.1%) ICIs patients resulted positive, with a significant lower percentage in respect to CHTs patients (39 positive subjects out of 598, 6.5%) (p = 0.04). There was no statistically significant difference between ICIs cohort and healthcare providers, 48 out of 1050 resulting positive (4.6%). Performing a Propensity Score Matching based on gender and tumor stage, the effect of treatment on seropositivity was analyzed through a regression logistic model and the ICIs treatment resulted to be the only protective factor significantly (p = 0.03) associated with positivity (odds ratio—OR: 0.41; 95% confidence interval—CI 0.18–0.91). According to these preliminary data, ICIs would appear to be a protective factor against the onset of COVID-19 infection.
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