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- Abou Selo, O, et al.
(författare)
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Private Function Evaluation Using Intel's SGX
- 2020
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Ingår i: SECURITY AND COMMUNICATION NETWORKS. - : Hindawi Limited. - 1939-0114 .- 1939-0122. ; 2020
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Private Function Evaluation (PFE) is the problem of evaluating one party’s private data using a private function owned by another party. Existing solutions for PFE are based on universal circuits evaluated in secure multiparty computations or on hiding the circuit’s topology and the gate’s functionality through additive homomorphic encryption. These solutions, however, are not efficient enough for practical use; hence there is a need for more efficient techniques. This work looks at utilizing the Intel Software Guard Extensions platform (SGX) to provide a more practical solution for PFE where the privacy of the data and the function are both preserved. Notably, our solution carefully avoids the pitfalls of side-channel attacks on SGX. We present solutions for two different scenarios: the first is when the function’s owner has an SGX-enabled device and the other is when a third party (or one of the data owners) has the SGX capability. Our results show a clear expected advantage in terms of running time for the first case over the second. Investigating the slowdown in the second case leads to the garbling time which constitutes more than 60% of the consumed time. Both solutions clearly outperform FairplayPF in our tests.
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| 6. |
- Tamborero, D, et al.
(författare)
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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology
- 2022
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Ingår i: Nature cancer. - : Springer Science and Business Media LLC. - 2662-1347. ; 3:2, s. 251-
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Tidskriftsartikel (refereegranskat)abstract
- There is a growing need for systems that efficiently support the work of medical teams at the precision-oncology point of care. Here, we present the implementation of the Molecular Tumor Board Portal (MTBP), an academic clinical decision support system developed under the umbrella of Cancer Core Europe that creates a unified legal, scientific and technological platform to share and harness next-generation sequencing data. Automating the interpretation and reporting of sequencing results decrease the need for time-consuming manual procedures that are prone to errors. The adoption of an expert-agreed process to systematically link tumor molecular profiles with clinical actions promotes consistent decision-making and structured data capture across the connected centers. The use of information-rich patient reports with interactive content facilitates collaborative discussion of complex cases during virtual molecular tumor board meetings. Overall, streamlined digital systems like the MTBP are crucial to better address the challenges brought by precision oncology and accelerate the use of emerging biomarkers.
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