| 1. |
- Aminalragia-Giamini, Sigiava, et al.
(författare)
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Solar Energetic Particle Event occurrence prediction using Solar Flare Soft X-ray measurements and Machine Learning
- 2021
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Ingår i: Journal of Space Weather and Space Climate. - : EDP Sciences. - 2115-7251. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- The prediction of the occurrence of Solar Energetic Particle (SEP) events has been investigated over many years, and multiple works have presented significant advances in this problem. The accurate and timely prediction of SEPs is of interest to the scientific community as well as mission designers, operators, and industrial partners due to the threat SEPs pose to satellites, spacecrafts, and crewed missions. In this work, we present a methodology for the prediction of SEPs from the soft X-rays of solar flares associated with SEPs that were measured in 1 AU. We use an expansive dataset covering 25 years of solar activity, 1988-2013, which includes thousands of flares and more than two hundred identified and catalogued SEPs. Neural networks are employed as the predictors in the model, providing probabilities for the occurrence or not of a SEP, which are converted to yes/no predictions. The neural networks are designed using current and state-of-the-art tools integrating recent advances in the machine learning field. The results of the methodology are extensively evaluated and validated using all the available data, and it is shown that we achieve very good levels of accuracy with correct SEP occurrence prediction higher than 85% and correct no-SEP predictions higher than 92%. Finally, we discuss further work towards potential improvements and the applicability of our model in real-life conditions.
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| 2. |
- Fusai, Giuseppe Kito, et al.
(författare)
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Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- 2023
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Ingår i: British Journal of Surgery. - : OXFORD UNIV PRESS. - 0007-1323 .- 1365-2168.
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Tidskriftsartikel (refereegranskat)abstract
- Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide. Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters. Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries. Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761).
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| 3. |
- Jaczewska, Justyna, et al.
(författare)
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Ordering domains of spin cast blends of conjugated and dielectric polymers on surfaces patterned by soft- and photo-lithography
- 2009
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Ingår i: Soft Matter. - London : Royal Society of Chemistry. - 1744-683X. ; 5:1, s. 234-241
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Tidskriftsartikel (refereegranskat)abstract
- Spin casting polymer blends of conjugated and dielectric macromolecules onto chemically patterned metal and oxidized silicon surfaces might provide a simple method to fabricate polymer-based circuitries that can be integrated with conventional electronics. Such solution-processing of the blend components offers simultaneous deposition and pattern-directed alignment of the phase separated polymer domains. The alignment is driven by self-organization guided by preferential surface segregation. Here we demonstrate that the laterally arranged domain structures in spin cast films of theconjugated poly(3-alkylthiophenes) (P3ATs): P3BT, P3DDT and regioregular R-P3HT, blended with dielectric polystyrene (PS), can be ordered by three different surface templates. The templates are formed by a patterned self-assembled monolayer (SAM), micro-contact printed on the surface of interest, i.e. hexadecanethiols on gold (for alignment of P3DDT/PS blend) and octadecyltrichlorosilanes on oxidized silicon (for R-P3HT/PS). Additionally gold lines are micropatterned on SiO2 with photo-lithography (for P3BT/PS mixture). The forces driving pattern-directed self-organization of the polymers are discussed based on complementary studies of preferential surface segregation, observed for blend films spin cast on homogeneous surfaces that correspond to the different regions of the surface templates
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