| 1. |
- Ren, Shan, et al.
(författare)
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Influence of B2O3 on Viscosity of High Ti-bearing Blast Furnace Slag
- 2012
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Ingår i: ISIJ International. - : Iron and Steel Institute of Japan. - 0915-1559 .- 1347-5460. ; 52:6, s. 984-991
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Tidskriftsartikel (refereegranskat)abstract
- The influence of B2O3 on the viscosity of high Ti-bearing BF slag is studied under Ar atmosphere from 1 773 K (1 500 degrees C) to about 1 593 K (1 320 degrees C). The results show that the addition of B2O3 can decrease the viscosity of high Ti-bearing BF Slag containing UPC, consequently improve its fluidity. With the existence of 1.5% UPC, when the content of B2O3 increased from 0 to 4.1%, the volume fraction of perovskite decreased from 7.7% to 1.6% at 1 610 K. Meanwhile, the liquidus temperatures decreased from 1 619 K to 1 613 K. At a lower temperature, B2O3 was easy to form a eutectic and decreased the viscosity of molten slag. At a higher temperature, some tetrahedron [BO4](5-) changed into triangle [BO3](3-) which would disintegrate the chains/molecules of molten matrix and decreased its viscosity.
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| 2. |
- Ren, Yanan, et al.
(författare)
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3DOM-NiFe2O4 as an effective catalyst for turning CO2 and H2O into fuel (CH4)
- 2018
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Ingår i: Journal of Sol-Gel Science and Technology. - : SPRINGER. - 0928-0707 .- 1573-4846. ; 88:3, s. 489-496
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Forskningsöversikt (refereegranskat)abstract
- Three-dimensional ordered macroporous NiFe2O4 (3DOM-NFO) powder was synthesized through the direct templating method combined with the sol-gel combustion technique. Polymethyl methacrylate (PMMA) spheres with different sizes were used as the hard templates. In order to understand the effect of PMMA spheres mean size on the structure and catalytic activity of synthesized 3DOM-NFO, the detailed characterization of the material was carried out by XRD, SEM, BET, XPS, UV-VIS, and DRS techniques. Direct hydrogeneration production of CH4 from CO2 and H2O was used to evaluate the catalysis performance of 3DOM-NFOs. The production of CH4 evolution can reach 1040.8mol/g at 350 degrees C and ambient pressure when 300nm template was used. It was concluded that the specific surface area and moderate concentration of oxygen vacancies are the crucial factors affecting the catalysis properties. Reasonably high turnover number of 0.244 and high CH4 conversion efficiency of 0.897% were obtained in this study. 3DOM-NFO can be a promising catalyst for hydrocarbon fuel production by directly using CO2 and H2O as the safe and cheap feedstocks. [GRAPHICS] .
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| 3. |
- Wang, Ying, et al.
(författare)
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Screening for differentially expressed circRNA between Kashin–Beck disease and osteoarthritis patients based on circRNA chips
- 2020
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Ingår i: Clinica Chimica Acta. - : Elsevier. - 0009-8981 .- 1873-3492. ; 501, s. 92-101
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Tidskriftsartikel (refereegranskat)abstract
- Objective: This research aims to explore differentially expressed circRNA between OA and KBD and potential diagnostic biomarkers.Methods: Total RNA was extracted from 5 pairs of KBD and OA knee joint cartilage specimens, and the expression of circRNAs was analyzed by Chip Scanning Analysis. The microarray data was verified by quantitative polymerase chain reaction (qRT-PCR). CircRNA-miRNA network was constructed to predict targeting microRNAs of circRNA genes. Peripheral blood samples from 25 KBD patients and 25 OA patients were collected for verification by qRT-PCR. Diagnostic value was evaluated by the area under the receiver operator characteristic (ROC) curve.Results: A total of 1627 circRNAs were differentially expressed between OA and KBD. Five bone and joint disease-related circRNAs were chosen for qRT-PCR validation. The difference in expression profile of hsa_circRNA_0020014 was confirmed by qRT-PCR, and its circRNA-miRNA regulation network was set up. The ROC curve demonstrated that hsa_circ_0020014_CBC1 in peripheral blood could distinguish patients with KBD and OA.Conclusion: The expression profiles of circRNA were significantly different between OA and KBD. hsa_circRNA_0020014 is a potential biomarker for differential diagnosis between these two diseases.
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| 4. |
- Wang, Ying, et al.
(författare)
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Screening for Differentially Expressed Circular RNAs in the Cartilage of Osteoarthritis Patients for Their Diagnostic Value
- 2019
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Ingår i: Genetic Testing and Molecular Biomarkers. - : Mary Ann Liebert. - 1945-0265 .- 1945-0257. ; 23:10, s. 706-716
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Tidskriftsartikel (refereegranskat)abstract
- Background: Osteoarthritis (OA) is the most prevalent osteoarticular disease, which typically involves chronic cartilage degeneration and synovitis. The latest research shows that circular RNAs (circRNAs) play a role in the development of a variety of diseases, including osteoarthrosis.Purposes: The aim of this study was to explore the expression of circRNAs in OA chondrocytes and predict biomarkers for diagnosis.Materials and Methods: The circRNA expression profile was analyzed through use of the Gene Spring software V13.0; differentially expressed circRNAs were screened by comparing OA chondrocytes and normal articular chondrocytes. We validated the microarray data by quantitative real-time polymerase chain reaction analyses of OA chondrocytes and chondrocytes from normal controls. TargetScan software and miRanda software were used to predict networks of circRNA–miRNA interactions in cartilage. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and Gene Ontology (GO) analyses were applied to predict the functions of differentially expressed circRNAs.Results: Overall, 1380 circRNAs were differentially expressed between OA chondrocytes and normal articular chondrocytes (fold-change ≥2, p ≤ 0.05), including 215 that were upregulated and 1165 that were downregulated circRNAs. After analyzing the differentially expressed circRNA genes, the top 20 enriched GO entries and KEGG pathways were annotated. The hsa_circrna_0032131 was identified for further analysis. A circRNA–miRNA network was constructed to represent the 10 most likely target genes associated with the validated circRNA.Conclusions: Our research suggests that some of the differentially expressed circRNAs in OA chondrocytes compared to normal chondrocytes are etiologically associated with the pathological process of OA. It was found that hsa_circRNA_0032131 likely participates in the initiation and progression of OA and has potential as a diagnostic marker.Clinical Relevance: To analyze the difference of circRNA expression profiles between OA and normal controls and explore biomarkers for diagnosis.
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