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| 2. |
- Jönsson, Josefine, et al.
(författare)
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Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation, Which Associates With Body Composition in the Offspring
- 2021
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Ingår i: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 70:4, s. 854-866
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Tidskriftsartikel (refereegranskat)abstract
- Maternal obesity may lead to epigenetic alterations in the offspring and might thereby contribute to disease later in life. We investigated whether a lifestyle intervention in pregnant women with obesity is associated with epigenetic variation in cord blood and body composition in the offspring. Genome-wide DNA methylation was analyzed in cord blood from 208 offspring from the Treatment of Obese Pregnant women (TOP)-study, which includes pregnant women with obesity randomized to lifestyle interventions comprised of physical activity with or without dietary advice versus control subjects (standard of care). DNA methylation was altered at 379 sites, annotated to 370 genes, in cord blood from offspring of mothers following a lifestyle intervention versus control subjects (false discovery rate [FDR] <5%) when using the Houseman reference-free method to correct for cell composition, and three of these sites were significant based on Bonferroni correction. These 370 genes are overrepresented in gene ontology terms, including response to fatty acids and adipose tissue development. Offspring of mothers included in a lifestyle intervention were born with more lean mass compared with control subjects. Methylation at 17 sites, annotated to, for example, DISC1, GBX2, HERC2, and HUWE1, partially mediates the effect of the lifestyle intervention on lean mass in the offspring (FDR <5%). Moreover, 22 methylation sites were associated with offspring BMI z scores during the first 3 years of life (P < 0.05). Overall, lifestyle interventions in pregnant women with obesity are associated with epigenetic changes in offspring, potentially influencing the offspring's lean mass and early growth.
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| 3. |
- Liu, Jia, et al.
(författare)
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An Organic Catalyst for Li-O-2 Batteries : Dilithium Quinone-1,4-Dicarboxylate
- 2015
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Ingår i: ChemSusChem. - : Wiley. - 1864-5631 .- 1864-564X. ; 8:13, s. 2198-2203
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Tidskriftsartikel (refereegranskat)abstract
- Solid organic electrocatalysts have hardly been tested in Li-O-2 batteries. Here, a new solid organic electrocatalyst, dilithium quinone-1,4-dicarboxylate (Li2C8H2O6) is presented, which is expected to overcome the shortcomings of inorganic catalysts. The function-oriented synthesis is low cost and low polluting. The electrocatalytic performance is evaluated by following the degradation of Li2O2 during the charge process in a Li-O-2 cell through insitu XRD and operando synchrotron radiation powder XRD (SR-PXD) measurements. The results indicate that the electrocatalytic activity of Li2C8H2O6 is similar to that of commercial Pt. The Li2O2 decomposition in a cell with Li2C8H2O6 catalyst follows a pseudo-zero-order reaction, virtually without any side reactions. These results provide an insight into the development of new organic catalysts for the oxygen evolution reaction (OER) in Li-O-2 batteries.
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| 5. |
- Renault, Stevén, et al.
(författare)
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Dilithium 2-aminoterephthalate as a negative electrode material for lithium-ion batteries
- 2017
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Ingår i: Solid State Ionics. - : Elsevier BV. - 0167-2738 .- 1872-7689. ; 307, s. 1-5
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Tidskriftsartikel (refereegranskat)abstract
- This work presents the synthesis and characterization of a novel organic Li-battery anode material: dilithium 2-aminoterephthalate (C8H5Li2NO4). When investigated in Li half-cells, the resulting electrodes show stable capacities around ca. 180 mAh g− 1 and promising rate capabilities, with battery performance at 500 mA g− 1 and good capacity recovery, despite being an asymmetric compound. DFT calculations indicate a preferential lithiation on carboxylates close to the amino group.
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| 7. |
- Renault, Stéven, et al.
(författare)
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Environmentally-Friendly Lithium Recycling From a Spent Organic Li-Ion Battery
- 2014
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Ingår i: ChemSusChem. - : Wiley. - 1864-5631 .- 1864-564X. ; 7:10, s. 2859-2867
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Tidskriftsartikel (refereegranskat)abstract
- A simple and straightforward method using non-polluting solvents and a single thermal treatment step at moderate temperature was investigated as an environmentally-friendly process to recycle lithium from organic electrode materials for secondary lithium batteries. This method, highly dependent on the choice of electrolyte, gives up to 99% of sustained capacity for the recycled materials used in a second life-cycle battery when compared with the original. The best results were obtained using a dimethyl carbonate/lithium bis(trifluoromethane sulfonyl) imide electrolyte that does not decompose in presence of water. The process implies a thermal decomposition step at a moderate temperature of the extracted organic material into lithium carbonate, which is then used as a lithiation agent for the preparation of fresh electrode material without loss of lithium.
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| 10. |
- Renault, Stevén, et al.
(författare)
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Improving the electrochemical performance of organic Li-ion battery electrodes
- 2013
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 49:19, s. 1945-1947
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Tidskriftsartikel (refereegranskat)abstract
- Dilithium benzenediacrylate was prepared and investigated as an example of a readily available organic electrode material for lithium-ion batteries. Its poor conductive properties were overcome by a method of carbon-coating in the liquid state, resulting in enhanced cycling performance, displaying a reversible capacity of 180 mA h g(-1).
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