| 1. |
- Marconi, A., et al.
(författare)
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ANDES, the high resolution spectrograph for the ELT : science case, baseline design and path to construction
- 2022
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Ingår i: GROUND-BASED AND AIRBORNE INSTRUMENTATION FOR ASTRONOMY IX. - : SPIE - International Society for Optical Engineering. - 9781510653504 - 9781510653498
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Konferensbidrag (refereegranskat)abstract
- The first generation of ELT instruments includes an optical-infrared high resolution spectrograph, indicated as ELT-HIRES and recently christened ANDES (ArmazoNes high Dispersion Echelle Spectrograph). ANDES consists of three fibre-fed spectrographs (UBV, RIZ, YJH) providing a spectral resolution of similar to 100,000 with a minimum simultaneous wavelength coverage of 0.4-1.8 mu m with the goal of extending it to 0.35-2.4 mu m with the addition of a K band spectrograph. It operates both in seeing- and diffraction-limited conditions and the fibre-feeding allows several, interchangeable observing modes including a single conjugated adaptive optics module and a small diffraction-limited integral field unit in the NIR. Its modularity will ensure that ANDES can be placed entirely on the ELT Nasmyth platform, if enough mass and volume is available, or partly in the Coude room. ANDES has a wide range of groundbreaking science cases spanning nearly all areas of research in astrophysics and even fundamental physics. Among the top science cases there are the detection of biosignatures from exoplanet atmospheres, finding the fingerprints of the first generation of stars, tests on the stability of Nature's fundamental couplings, and the direct detection of the cosmic acceleration. The ANDES project is carried forward by a large international consortium, composed of 35 Institutes from 13 countries, forming a team of more than 200 scientists and engineers which represent the majority of the scientific and technical expertise in the field among ESO member states.
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| 2. |
- Abbadessa, G, et al.
(författare)
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Unsung hero Robert C. Gallo
- 2009
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 323:5911, s. 206-207
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 4. |
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| 5. |
- Roederer, Ian U., et al.
(författare)
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Element abundance patterns in stars indicate fission of nuclei heavier than uranium
- 2023
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Ingår i: Science. - 0036-8075 .- 1095-9203. ; 382:6675
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Tidskriftsartikel (refereegranskat)abstract
- The heaviest chemical elements are naturally produced by the rapid neutron-capture process (r-process) during neutron star mergers or supernovae. The r-process production of elements heavier than uranium (transuranic nuclei) is poorly understood and inaccessible to experiments so must be extrapolated by using nucleosynthesis models. We examined element abundances in a sample of stars that are enhanced in r-process elements. The abundances of elements ruthenium, rhodium, palladium, and silver (atomic numbers Z = 44 to 47; mass numbers A = 99 to 110) correlate with those of heavier elements (63 <= Z <= 78, A > 150). There is no correlation for neighboring elements (34 <= Z <= 42 and 48 <= Z <= 62). We interpret this as evidence that fission fragments of transuranic nuclei contribute to the abundances. Our results indicate that neutron-rich nuclei with mass numbers >260 are produced in r-process events.
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| 6. |
- Roederer, Ian U., et al.
(författare)
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The R-process Alliance : A Nearly Complete R-process Abundance Template Derived from Ultraviolet Spectroscopy of the R-process-enhanced Metal-poor Star HD 222925*
- 2022
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Ingår i: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 260:2, s. 1-29
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Tidskriftsartikel (refereegranskat)abstract
- We present a nearly complete rapid neutron-capture process (r-process) chemical inventory of the metal-poor ([Fe/H] = −1.46 ± 0.10) r-process-enhanced ([Eu/Fe] = +1.32 ± 0.08) halo star HD 222925. This abundance set is the most complete for any object beyond the solar system, with a total of 63 metals detected and seven with upper limits. It comprises 42 elements from 31 ≤ Z ≤ 90, including elements rarely detected in r-process-enhanced stars, such as Ga, Ge, As, Se, Cd, In, Sn, Sb, Te, W, Re, Os, Ir, Pt, and Au. We derive these abundances from an analysis of 404 absorption lines in ultraviolet spectra collected using the Space Telescope Imaging Spectrograph on the Hubble Space Telescope and previously analyzed optical spectra. A series of appendices discusses the atomic data and quality of fits for these lines. The r-process elements from Ba to Pb, including all elements at the third r-process peak, exhibit remarkable agreement with the solar r-process residuals, with a standard deviation of the differences of only 0.08 dex (17%). In contrast, deviations among the lighter elements from Ga to Te span nearly 1.4 dex, and they show distinct trends from Ga to Se, Nb through Cd, and In through Te. The r-process contribution to Ga, Ge, and As is small, and Se is the lightest element whose production is dominated by the r-process. The lanthanide fraction, log XLa = −1.39 ± 0.09, is typical for r-process-enhanced stars and higher than that of the kilonova from the GW170817 neutron-star merger event. We advocate adopting this pattern as an alternative to the solar r-process-element residuals when confronting future theoretical models of heavy-element nucleosynthesis with observations.
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| 7. |
- Roederer, Ian U., et al.
(författare)
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The R-Process Alliance : Abundance Universality among Some Elements at and between the First and Second R-Process Peaks
- 2022
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 936:1
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Tidskriftsartikel (refereegranskat)abstract
- We present new observational benchmarks of rapid neutron-capture process (r-process) nucleosynthesis for elements at and between the first (A ∼ 80) and second (A ∼ 130) peaks. Our analysis is based on archival ultraviolet and optical spectroscopy of eight metal-poor stars with Se (Z = 34) or Te (Z = 52) detections, whose r-process enhancement varies by more than a factor of 30 (−0.22 ≤ [Eu/Fe] ≤ +1.32). We calculate ratios among the abundances of Se, Sr through Mo (38 ≤ Z ≤ 42), and Te. These benchmarks may offer a new empirical alternative to the predicted solar system r-process residual pattern. The Te abundances in these stars correlate more closely with the lighter r-process elements than the heavier ones, contradicting and superseding previous findings. The small star-to-star dispersion among the abundances of Se, Sr, Y, Zr, Nb, Mo, and Te (≤0.13 dex, or 26%) matches that observed among the abundances of the lanthanides and third r-process-peak elements. The concept of r-process universality that is recognized among the lanthanide and third-peak elements in r-process-enhanced stars may also apply to Se, Sr, Y, Zr, Nb, Mo, and Te, provided the overall abundances of the lighter r-process elements are scaled independently of the heavier ones. The abundance behavior of the elements Ru through Sn (44 ≤ Z ≤ 50) requires further study. Our results suggest that at least one relatively common source in the early Universe produced a consistent abundance pattern among some elements spanning the first and second r-process peaks.
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| 8. |
- Shah, Shivani P., et al.
(författare)
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The R-Process Alliance : detailed chemical composition of an r-process enhanced star with UV and optical spectroscopy
- 2024
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Ingår i: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 529:3, s. 1917-1940
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Tidskriftsartikel (refereegranskat)abstract
- We present a detailed chemical-abundance analysis of a highly r-process-enhanced (RPE) star, 2MASS J00512646-1053170, using high-resolution spectroscopic observations with Hubble Space Telescope/STIS in the UV and Magellan/MIKE in the optical. We determined abundances for 41 elements in total, including 23 r-process elements and rarely probed species such as Al II, Ge I, Mo II, Cd I, Os II, Pt I, and Au I. We find that [Ge/Fe] = +0.10, which is an unusually high Ge enhancement for such a metal-poor star and indicates contribution from a production mechanism decoupled from that of Fe. We also find that this star has the highest Cd abundance observed for a metal-poor star to date. We find that the dispersion in the Cd abundances of metal-poor stars can be explained by the correlation of Cd I abundances with the stellar parameters of the stars, indicating the presence of NLTE effects. We also report that this star is now only the sixth star with Au abundance determined. This result, along with abundances of Pt and Os, uphold the case for the extension of the universal r-process pattern to the third r-process peak and to Au. This study adds to the sparse but growing number of RPE stars with extensive chemical-abundance inventories and highlights the need for not only more abundance determinations of these rarely probed species, but also advances in theoretical NLTE and astrophysical studies to reliably understand the origin of r-process elements.
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| 9. |
- Dahlqvist, Johanna, 1979-, et al.
(författare)
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Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease
- 2021
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Ingår i: Human Molecular Genetics. - : Oxford University Press. - 0964-6906 .- 1460-2083.
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Tidskriftsartikel (refereegranskat)abstract
- Background: FCGR2A binds antibody–antigen complexes to regulate the abundance of circulating and deposited complexes along with downstream immune and autoimmune responses. Although the abundance of FCRG2A may be critical in immune-mediated diseases, little is known about whether its surface expression is regulated through cis genomic elements and non-coding variants. In the current study, we aimed to characterize the regulation of FCGR2A expression, the impact of genetic variation and its association with autoimmune disease. Methods: We applied CRISPR-based interference and editing to scrutinize 1.7 Mb of open chromatin surrounding the FCGR2A gene to identify regulatory elements. Relevant transcription factors (TFs) binding to these regions were defined through public databases. Genetic variants affecting regulation were identified using luciferase reporter assays and were verified in a cohort of 1996 genotyped healthy individuals using flow cytometry. Results: We identified a complex proximal region and five distal enhancers regulating FCGR2A. The proximal region split into subregions upstream and downstream of the transcription start site, was enriched in binding of inflammation-regulated TFs, and harbored a variant associated with FCGR2A expression in primary myeloid cells. One distal enhancer region was occupied by CCCTC-binding factor (CTCF) whose binding site was disrupted by a rare genetic variant, altering gene expression. Conclusions: The FCGR2A gene is regulated by multiple proximal and distal genomic regions, with links to autoimmune disease. These findings may open up novel therapeutic avenues where fine-tuning of FCGR2A levels may constitute a part of treatment strategies for immune-mediated diseases.
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