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- Hollo, G, et al.
(författare)
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Referral for first glaucoma surgery in Europe, the ReF-GS study
- 2019
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Ingår i: European journal of ophthalmology. - : SAGE Publications. - 1724-6016 .- 1120-6721. ; 29:4, s. 406-416
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Tidskriftsartikel (refereegranskat)abstract
- To analyze the appropriateness of referrals for incisional glaucoma-surgery in Europe. Methods: Referrals for the first open-angle glaucoma surgery between January and October 2017 were analyzed in 18 countries: 8 “old” European Union, 7 “new” European Union and 3 non-European Union European countries. Results: Most eyes had primary open-angle or exfoliative glaucoma. The average mean deviation was −13.8 dB with split fixation in 44.3%. No structural progression analysis was made before the referrals. The most common medications were the combination of a prostaglandin analog, timolol and a carbonic anhydrase inhibitor (30.0%), and all other combinations comprising ⩾ 3 molecules (33.8%). Laser trabeculoplasty was reported in only 18.4%. Of the 294 referrals, 41.5% were appropriate and timely, 35.0% appropriate but later than optimal, and 17.6% appropriate but too late (minimal vision maintained). The treatment period was significantly longer (median: 7 years) in the “old” European Union countries than in the other groups (3 and 2 years, respectively). No between-group differences were seen in intraocular pressure and mean deviation, but the non-European Union group referred the patients at significantly lower cup/disk ratio and eye drop usage than the other groups. Split fixation was significantly more common in the “old” (60.6%) than the “new” European Union countries (38.7%), and in both EU country-groups than in the non-European Union countries (13.6%). Conclusions: Of 294 European open-angle glaucoma referrals for first glaucoma-surgery, 41.5% were completely satisfactory. The damage was typically advanced, and the care varied considerably among the countries. This suggests that further efforts are necessary to improve glaucoma care in Europe.
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- Schulenberg, T., et al.
(författare)
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European supercritical water cooled reactor
- 2011
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Ingår i: Nuclear Engineering and Design. - : Elsevier BV. - 0029-5493 .- 1872-759X. ; 241:9, s. 3505-3513
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Tidskriftsartikel (refereegranskat)abstract
- The High Performance Light Water Reactor (HPLWR), how the European Supercritical Water Cooled Reactor is called, is a pressure vessel type reactor operated with supercritical water at 25 MPa feedwater pressure and 500 degrees C average core outlet temperature. It is designed and analyzed by a European consortium of 10 partners and 3 active supporters from 8 Euratom member states in the second phase of the HPLWR project. Most emphasis has been laid on a core with a thermal neutron spectrum, consisting of small fuel assemblies in boxes with 40 fuel pins each and a central water box to improve the neutron moderation despite the low coolant density. Peak cladding temperatures of the fuel rods have been minimized by heating up the coolant in three steps with intermediate coolant mixing. The containment design with its safety and residual heat removal systems is based on the latest boiling water reactor concept, but with different passive high pressure coolant injection systems to cause a forced convection through the core. The design concept of the steam cycle is indicating the envisaged efficiency increase to around 44%. Moreover, it provides the constraints to design the components of the balance of the plant. The project is accompanied by numerical studies of heat transfer of supercritical water in fuel assemblies and by material tests of candidate cladding alloys, performed by the consortium and supported by additional tests of the Joint Research Centre of the European Commission. Besides the scientific and technical progress, the HPLWR project turned out to be most successful in training the young generation of nuclear engineers in the technologies of light water reactors. More than 20 bachelor or master theses and more than 10 doctoral theses on HPLWR technologies have been submitted at partner organizations of this consortium since the start of this project.
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- Starflinger, J., et al.
(författare)
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European research activities within the project : "High Performance Light Water Reactor Phase 2" (HPLWR Phase 2)
- 2008
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Ingår i: Int. Congr. Adv. Nucl. Power Plants - ICAPP, "Nucl. Renaiss. Work". - 9781604238716 ; , s. 867-876
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Konferensbidrag (refereegranskat)abstract
- The High Performance Light Water Reactor (HPLWR) is a Light Water Reactor (LWR) operating at supercritical pressure (25MPa). It belongs to the six reactors currently being investigated under the framework of the Generation IV International Forum. The most visible advantage of the HPLWR shall be the low construction costs in the order of1000€/kWe, because of size reduction of components and buildings compared to current LWR, and the low electricity production costs which are targeted at 3-4cents/kWh. In Europe, investigations on the HPLWR have been integrated into a joint research project, called High Performance Light Water Reactor Phase 2 (HPLWR Phase 2), which is co-funded by the European Commission. Within 42 months, ten partners from eight European countries working on critical scientific issues shall show the feasibility of the HPLWR concept. The final goal is to assess the future potential of this reactor in the electricity market.
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- Starflinger, J., et al.
(författare)
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Progress within the European project : "High performance light water reactor phase 2" (HPLWR Phase 2)
- 2008
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Ingår i: International Conference on Advances in Nuclear Power Plants, ICAPP 2008. - 9781605607870 ; , s. 649-659
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Konferensbidrag (refereegranskat)abstract
- The High Performance Light Water Reactor (HPLWR) is a Light Water Reactor (LWR) operating at supercritical pressure (25MPa). It belongs to the six reactors currently being investigated under the framework of the Generation IV International Forum. In Europe, investigations on the HPLWR have been integrated into a joint research project, called High Performance Light Water Reactor Phase 2 (HPLWR Phase 2), which is co-funded by the European Commission. Within 42 months, ten partners from eight European countries working on critical scientific issues shall show the feasibility of the HPLWR concept. The final goal is to assess the future potential of this reactor in the electricity market. Within the first year of the project, mainly design tasks of the reactor core, the pressure vessel and its internals have been carried out and codes were adapted for supercritical fluid. Material oxidation experiments were performed and heat transfer was investigated numerically.
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- Starflinger, J., et al.
(författare)
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Results of the mid-term assessment of the "high performance light water reactor phase 2" project
- 2009
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Ingår i: International Congress on Advances in Nuclear Power Plants 2009, ICAPP 2009. - : Atomic Energy Society of Japan. - 9781617386084 ; , s. 501-511
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Konferensbidrag (refereegranskat)abstract
- The High Performance Light Water Reactor (HPLWR) is a Light Water Reactor (LWR) operating at supercritical pressure (p>22.1 MPa). In Europe, investigations on the HPLWR have been integrated into a joint research project, called High Performance Light Water Reactor Phase 2 (HPLWR Phase 2), which is co-funded by the European Commission. Within the second year of the project, the design of the reactor core, the pressure vessel and its internals have been analysed in detail by means of advanced codes and methods. The mechanical design has been assessed and shows that stresses inside components and possible deformations keep within acceptable limits. The neutronics and the flow inside the core have been investigated. The addition of a water layer in the reflector helps to flatten the radial power profile. The moderator flow path must be changed because of possible reverse flow in the gaps between the assemblies (downward flow). First calculations of transients showed an acceptable behaviour of the cladding temperatures. Material oxidation experiments were successfully performed. The auxiliary loop of the Supercritical Water Loop has been constructed. Heat transfer has been investigated numerically analysing heat transfer deterioration (HTD) and flow around fuel pins with wire wrap spacers.
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