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- Ambrosi, Aurelie, et al.
(författare)
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Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern
- 2012
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Ingår i: Annals of the Rheumatic Diseases. - London : BMJ Publishing Group. - 0003-4967 .- 1468-2060. ; 71:3, s. 334-340
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Tidskriftsartikel (refereegranskat)abstract
- Objective Congenital heart block may develop in the fetuses of Ro/SSA-positive and La/SSB-positive mothers. Recurrence rates of only 10-20% despite persisting maternal antibodies indicate that additional factors are critical for the establishment of heart block. The authors investigated the influence of other maternal and fetal factors on heart block development in a Swedish population-based cohort. less thanbrgreater than less thanbrgreater thanMethods The influence of fetal gender, maternal age, parity and time of birth on heart block development was analysed in 145 families, including Ro/La-positive (n=190) and Ro/La-negative (n=165) pregnancies. less thanbrgreater than less thanbrgreater thanResults There was a recurrence rate of 12.1% in Ro/La-positive women, and no recurrence in Ro/La-negative women. Fetal gender and parity did not influence the development of heart block in either group. Maternal age in Ro/La-positive pregnancies with a child affected by heart block was, however, significantly higher than in pregnancies resulting in babies without heart block (pandlt;0.05). Seasonal timing of pregnancy influenced the outcome. Gestational susceptibility weeks 18-24 occurring during January-March correlated with a higher proportion of children with heart block and lower vitamin D levels during the same period in a representative sample of Swedish women and a corresponding higher proportion of children with heart block born in the summer (pandlt;0.02). Maternal age or seasonal timing of pregnancy did not affect the outcome in Ro/La-negative pregnancies. less thanbrgreater than less thanbrgreater thanConclusion This study identifies maternal age and seasonal timing of pregnancy as novel risk factors for heart block development in children of Ro/La-positive women. These observations may be useful for counselling when pregnancy is considered.
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- Dymitrow, Mirek, et al.
(författare)
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Crossing dichotomies and breaking mental patterns: Green business development when all else fails?
- 2017
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Ingår i: 8th International Scientific Conference “Rural Development 2017: Bioeconomy Challenges”, 23–24 November, 2017 Kaunas, Lithuania.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Obtaining sustainable and inclusive societal organization is not merely a simple matter of ‘doing it’ by subscribing to some winning formula. Given that conceptual frameworks always guide our thoughts, judgments and actions (Latour, 2013; Harvey, 1996; Dennett, 1993), the ways in which we relate to concepts chosen to serve as guiding forces for future development will eventually determine its outcome. As scholarly evidence continuously suggests the concepts ‘rural’ and ‘urban’ are increasingly recognized as artificial barriers for conducting sound and integrated development endeavors in a globalized reality of interconnectedness. In line with the Sustainable Development Goals, which aim to eradicate poverty, shield the planet and safeguard prosperity for all, commitment to universal access to healthy food year round has become an important agenda point. This, however, has been exacerbated by binary thinking and separate ways of doing policy. This paper aims to share experiences from a unique project launched in the northern parts of Gothenburg, Sweden’s second largest city. While the area offers ample resources and immense opportunities for areal economies, it at the same time remains one of Gothenburg’s most segregated, with high levels of unemployment, ill health and crime. The uniqueness of the project lies not only in its way of abridging the rural-urban divide, but also by consciously deferring from the debilitating rhetoric of previous ‘immigrant policies’, and instead focusing on agricultural productivity, small-scale food producers and sustainable food strategies. Such exhortations to bridge between philosophical and material polarities, however, have not come without conceptual and practical challenges, something this paper aims to subsume and open up to debate.
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