| 1. |
- Edström, Krister, et al.
(författare)
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Modelling and Simulation of a Switched Power Converter
- 1996
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In our earlier work dealing with switched systems we have focused on the conceptual and formal side of the modelling process. In this paper we go one step further and illustrate the practical generation of simulation code from a switched bond graph. The principles are illustrated by means of an industrial switched power converter used to control the power of electric rotary machines. We describe an implementation of the formal Mode Transition System (MTS) presented earlier. The format proposed is referred to as Mode Transition File (MTF) format. We present an algorithm to generate the mode transition file from a switched bond graph. Finally we illustrate how this file format can be converted to code for the well known DASSRT solver.
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| 2. |
- Eriksson, Carl, 1981-, et al.
(författare)
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Long-term effectiveness of vedolizumab in inflammatory bowel disease : a national study based on the Swedish National Quality Registry for Inflammatory Bowel Disease (SWIBREG)
- 2017
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Ingår i: Scandinavian Journal of Gastroenterology. - : Taylor & Francis. - 0036-5521 .- 1502-7708. ; 52:6-7, s. 722-729
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Clinical trials have demonstrated the efficacy of vedolizumab in inflammatory bowel disease (IBD). However, these findings may not reflect the clinical practice. Therefore, we aimed to describe a vedolizumab-treated patient population and assess long-term effectiveness.Materials and methods: Patients initiating vedolizumab between 1 June 2014 and 30 May 2015 were identified through the Swedish National Quality Registry for IBD. Prospectively collected data on treatment and disease activity were extracted. Clinical remission was defined as Patient Harvey Bradshaw index<5 in Crohn's disease (CD) and Patient Simple Clinical Colitis Activity index<3 in ulcerative colitis (UC).Results: Two-hundred forty-six patients (147CD, 92 UC and 7 IBD-Unclassified) were included. On study entry, 86% had failed TNF-antagonist and 48% of the CD patients had undergone1 surgical resection. After a median follow-up of 17 (IQR: 14-20) months, 142 (58%) patients remained on vedolizumab. In total, 54% of the CD- and 64% of the UC patients were in clinical remission at the end of follow-up, with the clinical activity decreasing (p<.0001 in both groups). Faecal-calprotectin decreased in CD (p<.0001) and in UC (p=.001), whereas CRP decreased in CD (p=.002) but not in UC (p=.11). Previous anti-TNF exposure (adjusted HR: 4.03; 95% CI: 0.96-16.75) and elevated CRP at baseline (adjusted HR: 2.22; 95% CI: 1.10-4.35) seemed to be associated with discontinuation because of lack of response. Female sex was associated with termination because of intolerance (adjusted HR: 2.75; 95% CI: 1.16-6.48).Conclusion: Vedolizumab-treated patients represent a treatment-refractory group. A long-term effect can be achieved, even beyond 1 year of treatment.
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| 3. |
- Palm, David, et al.
(författare)
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Analys av lämpliga åtgärder för att öka återanvändning och återvinning av bygg- och rivningsavfall : Underlagsrapport för samhällsekonomisk analys
- 2015
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Det finns relativt stora mängder bygg och rivningsavfall som idag deponeras eller förbränns i blandade fraktioner. Genom att göra avfallshanteringen mer resurseffektiv finns det en stor potential att styra dessa mängder mot återanvändning och materialåtervinning. Uppgifter om hur stora mängder avfall som uppkommer inom bygg-, riv- och anläggningssektorn är relativt osäkra vilket medför att det är svårt att redogöraför hur mycket som skulle kunna återvinnas om rätt åtgärder och styrmedel införs.Syftet med projektet har varit att genomföra uppskattningar av de avfallsmängder som har påverkan på etappmålet för bygg- och rivningsavfall. Målet med projektet har varit att ta fram ett vetenskapligt underlag för åtgärder som kan användas för att nå etappmålet om minst 70 viktprocent förberedande till återanvändning, återanvändning och återvinning senast år 2020.I projektet har elva åtgärder analyserats, varav sju i detalj och fyra endast översiktligt, och föreslagits som underlag till Naturvårdsverkets fortsatta arbete med att styra marknaden i önskad riktning till 2020. Analysen visar dock att mängderna som ingår i återvinningsmålet för bygg- och rivningsavfall i verkligheten troligen är betydligt högre än vad som tidigare har rapporterats.
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| 4. |
- Strömberg, Jan-Erik, et al.
(författare)
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Bond Graph Supported Estimation of Discretely Changing Parameters
- 1993
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Ingår i: International Conference on Bond Graph Modeling, 1993. - 9781565550193 - 1565550196 ; , s. 47-52
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A key factor in parameter estimation is the selection of model structure within which the fit to observed data is to be achieved. For linear systems, bond graphs have proven to give excellent support in this respect. However, for systems undergoing abrupt transitions between different (linear) modes of behaviour, the situation is far more complex. To handle this, we exploit the features of the ideal switching element as introduced by Strömberg, Top and Söderman. This solves the question of physical modelling as well as how to derive the supporting information. The approach is demonstrated on a non-trivial example using a multiple Kalman filter estimator.
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| 5. |
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| 6. |
- Strömberg, Jan-Erik, et al.
(författare)
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Conceptual Modelling of Hybrid Systems
- 1994
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Ingår i: Proceedings of the 1994 European Simulation and Modelling Conference. - Linköping : Linköping University. ; , s. 1095-1099
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Rapport (övrigt vetenskapligt/konstnärligt)
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| 7. |
- Strömberg, Jan-Erik, et al.
(författare)
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Modelling and Simulation of a Switched Power Converter
- 1997
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Ingår i: Proceedings of the Third International Conference on Bond Graph Modeling and Simulation. - 1565551036 ; , s. 195-200
-
Konferensbidrag (refereegranskat)abstract
- In our earlier work dealing with switched systems we have focused on the conceptual and formal side of the modelling process. In this paper we go one step further and illustrate the practical generation of simulation code from a switched bond graph. The principles are illustrated by means of an industrial switched power converter used to control the power of electric rotary machines. We describe an implementation of the formal Mode Transition System (MTS) presented earlier. The format proposed is referred to as Mode Transition File (MTF) format. We present an algorithm to generate the mode transition file from a switched bond graph. Finally we illustrate how this file format can be converted to code for the well known DASSRT solver.
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| 8. |
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| 9. |
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| 10. |
- Strömberg, Jan-Erik, et al.
(författare)
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Variable Causality in Bond Graphs Caused by Discrete Effects
- 1993
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Ingår i: International Conference on Bond Graph Modeling, 1993. - 9781565550193 - 1565550196 ; , s. 115-119
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Current approaches to the problem of switching between modes in continuous dynamic system models tend to confound modelling and computation. Here we introduce an alternative approach ensuring a clear distinction between the physical and computational levels. Our method is centered around the idea that the variability of causal directions should be accepted rather than being alleviated. Hence, we define an ideal bond graph switching element, to deal with this variability in a bond graph uniform and systematic way. We hereby maintain the abstraction level of the bond graph language as well as the possibility to perform initial model validation directly in the graph.
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