| 1. |
- Gupta, Mohit Kumar, et al.
(författare)
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An Experimental Study of Microstructure : Property Relationships in Thermal Barrier Coatings
- 2013
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Ingår i: Journal of thermal spray technology (Print). - : Springer Science and Business Media LLC. - 1059-9630 .- 1544-1016. ; 22:5, s. 659-670
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Tidskriftsartikel (refereegranskat)abstract
- The thermal-mechanical properties of thermal barrier coatings are highly influenced by the defects present in coating microstructure. The aim of this study was to meet the future needs of the gas turbine industry by further development of zirconia coatings through the assessment of microstructure-property relationships. A design of experiments was conducted for this purpose with current, spray distance, and powder feed rate as the varied parameters. Microstructure was assessed with SEM and image analysis was used to characterize porosity content. Evaluations were carried out using laser flash technique to measure thermal properties. A bi-layer beam curvature technique in conjunction with controlled thermal cycling was used to assess the mechanical properties, in particular their nonlinear elastic response. Coating lifetime was evaluated by thermo-cyclic fatigue testing. Relationships between microstructure and coating properties are discussed. Dense vertically cracked microstructure and highly porous microstructure with large globular pores were also fabricated. Correlations between parameters obtained from nonlinear measurements and lifetime based on a priori established microstructural analysis were attempted in an effort to develop and identify a simplified strategy to assess coating durability following sustained long-term exposure to high temperature thermal cycling.
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| 2. |
- Hibar, Derrek P., et al.
(författare)
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Novel genetic loci associated with hippocampal volume
- 2017
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.
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| 3. |
- Vardelle, Armelle, et al.
(författare)
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Erratum to The 2016 Thermal Spray Roadmap
- 2017
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Ingår i: Journal of thermal spray technology (Print). - : Springer Science and Business Media LLC. - 1059-9630 .- 1544-1016. ; 26:5, s. 985-986
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Vardelle, Armelle, et al.
(författare)
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The 2016 Thermal Spray Roadmap
- 2016
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Ingår i: Journal of thermal spray technology (Print). - : Springer Science and Business Media LLC. - 1059-9630 .- 1544-1016. ; 25:8, s. 1376-1440
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Tidskriftsartikel (refereegranskat)abstract
- Considerable progress has been made over the last decades in thermal spray technologies, practices and applications. However, like other technologies, they have to continuously evolve to meet new problems and market requirements. This article aims to identify the current challenges limiting the evolution of these technologies and to propose research directions and priorities to meet these challenges. It was prepared on the basis of a collection of short articles written by experts in thermal spray who were asked to present a snapshot of the current state of their specific field, give their views on current challenges faced by the field and provide some guidance as to the R&D required to meet these challenges. The article is divided in three sections that deal with the emerging thermal spray processes, coating properties and function, and biomedical, electronic, aerospace and energy generation applications. © 2016, ASM International.
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