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Sökning: WFRF:(Sancheti Parag)

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1.
  • Altman, Roy D, et al. (författare)
  • Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee.
  • 2016
  • Ingår i: The American journal of sports medicine. - : SAGE Publications. - 1552-3365 .- 0363-5465. ; 44:8, s. 2158-2165
  • Tidskriftsartikel (refereegranskat)abstract
    • Knee osteoarthritis (OA) is a common and often disabling joint disorder among adults that may result in impaired activity and daily function. A variety of treatment options are currently available and prescribed for knee OA depending on the severity of the disorder and physician preference. Intra-articular hyaluronic acid (IA-HA) injection is a treatment for knee OA that reportedly provides numerous biochemical and biological benefits, including shock absorption, chondroprotection, and anti-inflammatory effects within the knee. Clarity is needed as to whether the available IA-HA products should be considered for therapy as a group or whether there are significant differences in the products that need to be considered in treatment of OA of the knee.
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3.
  • Li, Chuan Silvia, et al. (författare)
  • Orthopedic surgeons feel that there is a treatment gap in management of early OA: international survey.
  • 2014
  • Ingår i: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. - : Springer Science and Business Media LLC. - 1433-7347. ; 22, s. 363-378
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: To understand orthopedic surgeons' views, preferences, and awareness on "treatment gap" and various conservative and surgical treatments for early to mid-stage knee osteoarthritis (OA). METHODS: A self-administered questionnaire on the treatment of knee OA was developed in collaboration with orthopedic surgeons with extensive research experience and methodological expertise. The survey was distributed electronically to a group of international orthopedic surgeons and surgical trainees. The data were collected, reviewed, and analyzed using descriptive statistics. RESULTS: One hundred and seventy-three surgeons and surgical trainees completed the survey. The respondents reported that about 58% of the patients they treat have early to mid-stage knee OA (Kellgren and Lawrence grade I-III). There were significantly higher usage of medications and lower usage of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) (P<0.05) in developing countries than in developed countries. Four of five surgeons (84%) perceived a need for better treatments for younger (<60years old) physically active OA patients in which UKA or TKA is not indicated. Most respondents (80%) would be willing to adjust age/activity threshold for surgery if a procedure was reversible and recovery was minimal. Two of three surgeons (68.4%) perceived a treatment gap for early knee OA. However, effective treatments for patients within the treatment gap would have substantial positive social, and economic impacts. CONCLUSION: The study suggests an ongoing treatment gap for patients with early knee OA and the need for better evidence to guide practice.
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