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Sökning: WFRF:(Sandberg Erik)

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1.
  • Grip, Carl-Erik, et al. (författare)
  • Forestry meets Steel. A system study of the possibility to produce DRI (directly Reduced Iron) using gasified biomass.
  • 2015
  • Ingår i: ECOS 2015 - 28th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems. - : International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems. - 9782955553909
  • Konferensbidrag (refereegranskat)abstract
    • The main production of primy Iron from ore is now made by reduction using fossil reductants, either by producing hot metal in the blast furnace process or as directly reduced iron with natural gas as most common reductant. The climate gas impact would be improved if at least pt of the reductants could be produced from Biomass. One possibility could be to use gasified Biomass to produce DRI (Directly Reduced Iron). This is studied in a cooperative project where LTU, MEFOS, ETC and five industries in the eas forestry & pulp, mining, iron and gas e involved. The investigation is made in four pts where the first one is on the supply of biomass. A lge amount of Biomass has to be delivered into a single site to exchange a lge amount of fossil reductant. Also, forestry by-products should be used as most of the round wood is reserved for other uses. Hvesting, logistics and economics e considered. The second pt is on the gasification of the biomass, where the aim is to use to produce hot gas that can be used directly. Pilot experiments e cried out using oxygen in an entrained flow gasifier. The third pt is on the metallurgical processes, where reduction tests e cried out with gas that can be produced in the gasifier. The limitations of the gas content e studied as well as the effect on DRI. Also the suitability of the DRI product is evaluated. The fourth pt of the project uses process integration to model the whole process chain. The results from the other project pts e used to build the system model. It is then used for technical economic optimization the whole system hvesting- Transport-gasifier-direct reduction-use of DRI. The first use of the system model has been to find the best supply road (hvesting, pretreatment and transport) for a chosen production case The simulations indicated that the supply of residuals is possible but will need material from a lge pt of the north Sweden wood ea, and that a relatively lge amount of gas recirculation is needed. The continuing work is focused on further development of the optimization tool and the use of it for more extensive studies of the trade-off between pameters of metallurgy, gasification and supply. The result can be important for evaluation of future industrial applications. It could also help in understanding the effect of governmental control instruments. The paper will mainly focus on the process integration study.
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2.
  • Grip, Carl-Erik, et al. (författare)
  • Forestry meets Steel. A Technoeconomic study of the possible DRI production using biomass
  • 2015
  • Konferensbidrag (refereegranskat)abstract
    • The possibility to produce DRI using gasified Biomass is studied in a cooperative project. LTU, MEFOS, ETC and five industries in the areas forestry & pulp, mining, iron and gas are involved. The production chain Biomass production and distribution -Gasification-DRI production-DRI use is investigated in four work packages:WP1: Biomass supply: A large amount of Biomass has to be delivered into a single site to exchange a large amount of fossil reductant. It is important to use forestry by- products as a major part of round wood is reserved for other uses. Harvesting, logistics and economics have to be considered. Available data were collected and used to make a system model on harvesting treatment and transport. The simulations indicated that the supply of residuals is possible but will need material from a large part of the north Sweden wood area. WP2: Gasification. The aim is to use to produce hot gas that can be used directly. Pilot experiments are carried out using oxygen in an entrained flow gasifier. WP3: Metallurgical processes. Reduction tests are carried out with gas that can be produced in the gasifier. The limitations of the gas content are studied as well as the effect on DRI. Also the suitability of the DRI product is evaluated WP4: Process integration. A system model is built using the results from work packages 1-3 and used for technical economic optimization the whole system harvesting-transport-gasifier-direct reduction- use of DRI. The process chain is technically possible; however there are problems to be solved, e.g., gas quality vs. demands from DRI process, Biomass supply and logistics. The result is important to evaluate for industrial application, but also to get information of the effect of different governmental control instruments.
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4.
  • Kragh, Jörgen, et al. (författare)
  • Optimization of thin asphalt layers : state-of-the-art review
  • 2011
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • ERA-NET ROAD initiated a transnational research project titled "Optimization of thin asphalt layers" (OPTHINAL). The DRI-BRRC-VTI Consortium was trusted with carrying out the project and began with a State-of-the-Art report covering, among other things, a literature study and an inventory of experience with using thin asphalt layers (TAL). The results of this phase of the project are given in the present report.This study was limited to thin asphalt mixtures with a maximum thickness of 30 mm, which means that surface dressings or slurry seals were outside the scope of the project. Neither were top layers of double-layer porous pavements considered as TAL, even though such top layers often are 20-30 mm thick. Mix design and optimization was the subject of another study in this project and is therefore not treated here. The main conclusions are that the application of TAL is certainly worthwhile, in particular asa renewable “skin” of a stable road construction having sufficient bearing capacity. The skin serves road users’ need for sufficient skidding resistance and other important functions.
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5.
  • Kragh, Jörgen, et al. (författare)
  • Optimization of thin asphalt layers, OPTHINAL. Final report
  • 2011
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • ERA-NET ROAD initiated a transnational research project titled "Optimization of thin asphalt layers". Thin asphalt layers have been used extensively and with promising results for more than 15 years in several countries in Europe and abroad. They seem to be cost effective, fast to build and may have good surface properties. In recent years thin asphalt layers have been shown to imply reduced traffic noise levels, increased traffic safety (skid resistance and forward visibility during wet condition) and to be durable compared with traditional alternatives.The DRI-BRRC-VTI Consortium was trusted with carrying out the ERA-NET ROAD project and began with a State-of-the-Art report covering, among other things, a literature study and an inventory of experience with using thin asphalt layers. The results of this phase of the project were documented in a separate project report.The main conclusions were that the application of thin asphalt layers is certainly worthwhile, in particular as a renewable "skin" of a stable road construction having sufficient bearing capacity. The skin serves road users' need for skid resistance and other important functions. Compared with more conventional and traditional surfacing such as dense asphalt concrete 0/11 or stone mastic asphalt 0/11, thin asphalt layers in general come out somewhat better in most respects; for example concerning cost, use of nature resources, rolling resistance, and traffic noise emission. However, there are also drawbacks or problems under special traffic that need to be handled, for example TAL durability when exposed to wear from studded tyres. The availability of premium quality aggregate is a prerequisite for applying thin asphalt layers, and good quality aggregate may be difficult to procure.The present report looks at possibilities to optimize the application of thin asphalt layers, including an analysis of the cost of applying thin asphalt layers compared with the cost of applying more conventional solutions. The study has been limited to thin asphalt layers with a maximum thickness of 30 mm.Recommendations are given concerning the best practice in applying thin asphalt layers and suggestions are given for future research needed to fill the gaps in available knowledge.
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7.
  • Mold, Jeff E., et al. (författare)
  • Divergent clonal differentiation trajectories establish CD8(+) memory T cell heterogeneity during acute viral infections in humans
  • 2021
  • Ingår i: Cell Reports. - : Elsevier BV. - 2211-1247. ; 35:8
  • Tidskriftsartikel (refereegranskat)abstract
    • The CD8(+) T cell response to an antigen is composed of many T cell clones with unique T cell receptors, together forming a heterogeneous repertoire of effector and memory cells. How individual T cell clones contribute to this heterogeneity throughout immune responses remains largely unknown. In this study, we longitudinally track human CD8(+) T cell clones expanding in response to yellow fever virus (YFV) vaccination at the single-cell level. We observed a drop in clonal diversity in blood from the acute to memory phase, suggesting that clonal selection shapes the circulating memory repertoire. Clones in the memory phase display biased differentiation trajectories along a gradient from stem cell to terminally differentiated effector memory fates. In secondary responses, YFV- and influenza-specific CD8(+) T cell clones are poised to recapitulate skewed differentiation trajectories. Collectively, we show that the sum of distinct clonal phenotypes results in the multifaceted human T cell response to acute viral infections.
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8.
  • Sandberg, Christer, et al. (författare)
  • Effects of chip pretreatment and feeding segments on specific energy and pulp quality in TMP production
  • 2018
  • Ingår i: Nordic Pulp & Paper Research Journal. - : Walter de Gruyter GmbH. - 0283-2631 .- 2000-0669. ; 33:3, s. 448-459
  • Tidskriftsartikel (refereegranskat)abstract
    • Increased wood softening and refining intensity have earlier been utilized to improve refining efficiency in mechanical pulping. We have evaluated a combination of increased softening by low dose sulphite chip pretreatment and increased intensity by feeding segment design in a TMP line for production of high quality printing papers. Norway spruce wood chips were preheated, compressed in an Impressafiner and impregnated with water or sodium sulphite solutions (Na2SO3 charges 3.6 and 7.2 kg/t). Chips were refined in two parallel 68" double disc refiners using two different refining conditions: standard bidirectional segments at normal production rate (9 t/h) and feeding segments at increased production rate (11.1-12.1 t/h). The feeding segments enabled a 30 % increase in production rate. Refining with feeding segments at 12.1 t/h production rate combined with chip pretreatment with 3.6 kg/t sodium sulphite reduced the specific energy 360 kWh/t (19 %) compared to refining with standard segments and no pretreatment. Pulp properties were similar for the two configurations. The combination of feeding segments and chip pretreatment with water reduced the specific energy 180 kWh/t (9 %). Implementation of most of the technology presented has reduced the electrical energy use for the mill by approximately 80 GWh/year.
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9.
  • Sandberg, Johan V, et al. (författare)
  • Proteins associated with future suicide attempts in bipolar disorder: A large-scale biomarker discovery study
  • 2022
  • Ingår i: Molecular Psychiatry. - : Springer Science and Business Media LLC. - 1359-4184 .- 1476-5578.
  • Tidskriftsartikel (refereegranskat)abstract
    • Suicide is a major cause of death worldwide. Several biological systems have been implicated in suicidal behavior but studies of candidate biomarkers have failed to produce clinically relevant biomarkers for suicide prediction. The objective of the present study was to identify novel candidate biomarkers for suicidal behavior. We used a nested case-control study design where a large cohort of patients with bipolar disorder (N = 5 110) were followed up to 8 years after blood sampling. We included patients that attempted suicide during follow-up (N = 348) and matched bipolar disorder patients from the same cohort who did not attempt suicide during the study period (N = 348) and analyzed a total of 92 proteins with a neuro exploratory multiplex panel. Using a multivariate classification algorithm devised to minimize bias in variable selection, we identified a parsimonious set of proteins that best discriminated bipolar disorder patients with and without prospective suicide attempts. The algorithm selected 16 proteins for the minimal-optimal classification model, which outperformed 500 models with permuted outcome (p = 0.0004) but had low sensitivity (53%) and specificity (64%). The candidate proteins were then entered in separate logistic regression models to calculate protein-specific associations with prospective suicide attempts. In individual analyses, three of these proteins were significantly associated with prospective suicide attempt (SCGB1A1, ANXA10, and CETN2). Most of the candidate proteins are novel to suicide research.
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10.
  • Zackrisson, Erik, et al. (författare)
  • Hunting for dark halo substructure using submilliarcsecond-scale observations of macrolensed radio jets
  • 2013
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 431:3, s. 2172-2183
  • Tidskriftsartikel (refereegranskat)abstract
    • Dark halo substructure may reveal itself through secondary, small-scale gravitational lensing effects on light sources that are macrolensed by a foreground galaxy. Here, we explore the prospects of using Very Long Baseline Interferometry (VLBI) observations of multiply-imaged quasar jets to search for submilliarcsecond-scale image distortions produced by various forms of dark substructures in the 10(3)-10(8) M-circle dot mass range. We present lensing simulations relevant for the angular resolutions attainable with the existing European VLBI Network, the global VLBI array and an upcoming observing mode in which the Atacama Large Millimeter Array (ALMA) is connected to the global VLBI array. While observations of this type would not be sensitive to standard cold dark matter subhaloes, they can be used to detect the more compact forms of halo substructure predicted in alternative structure formation scenarios. By mapping approximately five strongly lensed systems, it should be possible to detect or robustly rule out primordial black holes in the 10(3)-10(6) M-circle dot mass range if they constitute greater than or similar to 1 per cent of the dark matter in these lenses. Ultracompact minihaloes are harder to detect using this technique, but 10(6)-10(8) M-circle dot ultracompact minihaloes could in principle be detected if they constitute greater than or similar to 10 per cent of the dark matter.
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