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- Sandberg, Ulf, 1946-, et al.
(författare)
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Rolling resistance : basic information and state-of-the-art on measurement methods. Final version
- 2011
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- MIRIAM has established a sub-project (SP), designated SP 1, to deal with measurement methods for rolling resistance and related issues. This subject forms the most fundamental basis for the MIRIAM ambition to consider rolling resistance in pavement management or other types of infrastructure systems. Without robust measurement methods and equipment that can use them there will be no reliable data as input to such systems and the end result will be most uncertain, if useful at all.In order to develop and study measurement methods, there must be a basic understanding of the influencing parameters as well as what energy losses that should be included in the concept of rolling resistance. These issues are, therefore, important parts of the work in SP 1.This report is intended to provide basic knowledge about the part of the tyre and road interaction which relates to rolling resistance; for example, the mechanisms that create rolling resistance, and the influence on rolling resistance of various tyre and road parameters. The intention is also to suggest a definition of rolling resistance for the purposes of this project, as well as to provide some detailed state-of-the-art knowledge about the measurement methods and equipment that are useful for collecting rolling resistance data.
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| 3. |
- Allen, Marie, et al.
(författare)
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Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles
- 1994
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Ingår i: Human Immunology. - 0198-8859 .- 1879-1166. ; 39:1, s. 41-8
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Tidskriftsartikel (refereegranskat)abstract
- The association of MS with HLA class II alleles was studied by PCR-based typing of the DQA1, DQB1, DRB1, and DPB1 loci in 94 Swedish patients with relapses and remissions of the disease. The haplotype DRB1*1501-DQA1*0102-DQB1*0602 was found to be positively associated and three haplotypes were found to be negatively associated with MS. Linkage disequilibrium makes it difficult to assess whether DRB1 or DQB1 plays the primary role in the disease association, while the association with DPB1 and DQA1 appears to be secondary to that of DQB1 and DRB1. Two of the three haplotypes negatively associated with MS carry the DQB1*0301 allele. Also, the negatively associated DRB1*0401-DQA1*0301-DQB1*0301 haplotype differs from those with nonassociated DRB1*0401-DQA1*0301-DQB1*0302 haplotype only at DQB1. These results suggest that DQB1 alleles, as well as some DRB1 alleles, are involved in susceptibility and protection to MS. In searching for sequence motifs in the DR beta chain associated with MS susceptibility, all DRB1 alleles on haplotypes positively associated with MS, including the DRB1*1501, were found to encode a Val at position 86 of the DR beta chain. Also, DRB1 alleles that are negatively associated with MS all encode a Gly at position 86, suggesting that the residue at position 86 may be critical in conferring susceptibility and protection to MS. Finally, when the effect of the DRB1*1501 haplotype was removed there was no support for the hypothesis that MS is associated with a putative DQ-alpha beta heterodimer, encoded for by certain DQA1 and DQB1 alleles.
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| 4. |
- Gustafsson, Mats, et al.
(författare)
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Effekter av vinterdäck : en kunskapsöversikt
- 2006
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Choice of winter tyres has, from mainly being a matter of safety and economic costs for wearing of road pavements, during later years also become a matter of inhalable particles formed during pavement wear from studded tyres and their negative effects on public health. Further, the tyres' effects on environment and noise have been illustrated in several studies. The issue is also complicated by the fact that tyre choice effects on traffic safety have several components, including such diverging parameters as friction and behaviour. Finally all aspects have to be evaluated from a socioeconomic point of view for society to be able to decide which kind of distribution of tyre types that is the most profitable. This report is a summary of current knowledge in this complex research field.
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| 9. |
- Alderborn, Anders, et al.
(författare)
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Genetically modified plants for non-food or non-feed purposes : straightforward screening for their appearance in food and feed
- 2010
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Ingår i: Food and Chemical Toxicology. - : Elsevier BV. - 0278-6915 .- 1873-6351. ; 48:2, s. 453-464
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Tidskriftsartikel (refereegranskat)abstract
- Genetically modified (GM) plants aimed at producing food/feed are part of regular agriculture in many areas of the World. Commodity plants have also found application as bioreactors, designated non-food/non-feed GM (NFGM) plants, thereby making raw material for further refinement to industrial, diagnostic or pharmaceutical preparations. Many among them may pose health challenge to consumers or livestock animals, if occurring in food/feed. NFGM plants are typically released into the environment, but are grown under special oversight and any among several containment practices, none of which provide full protection against accidental dispersal. Adventitious admixture with food or feed can occur either through distributional mismanagement or as a consequence of gene flow to plant relatives. To facilitate NFGM surveillance we propose a new mandatory tagging of essentially all such plants, prior to cultivation or marketing in the European Union. The suggested tag--Plant-Made Industrial or Pharmaceutical Products Tag (PMIP-T)--is envisaged to occur as a transgenic silent DNA identifier in host plants and designed to enable technically simple identification and characterisation of any NFGM. Implementation of PMIP-T would permit inexpensive, reliable and high-throughput screening for NFGM specifically. The paper outlines key NFGM prospects and challenges as well as the PMIP-T concept.
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