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Sökning: WFRF:(Schaefers M.)

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1.
  • Bailey, D. L., et al. (författare)
  • Combined PET/MRI : from Status Quo to Status Go. Summary Report of the Fifth International Workshop on PET/MR Imaging; February 15-19, 2016; Tubingen, Germany
  • 2016
  • Ingår i: Molecular Imaging and Biology. - : Springer Science and Business Media LLC. - 1536-1632 .- 1860-2002. ; 18:5, s. 637-650
  • Tidskriftsartikel (refereegranskat)abstract
    • This article provides a collaborative perspective of the discussions and conclusions from the fifth international workshop of combined positron emission tomorgraphy (PET)/magnetic resonance imaging (MRI) that was held in Tubingen, Germany, from February 15 to 19, 2016. Specifically, we summarise the second part of the workshop made up of invited presentations from active researchers in the field of PET/MRI and associated fields augmented by round table discussions and dialogue boards with specific topics. This year, this included practical advice as to possible approaches to moving PET/MRI into clinical routine, the use of PET/MRI in brain receptor imaging, in assessing cardiovascular diseases, cancer, infection, and inflammatory diseases. To address perceived challenges still remaining to innovatively integrate PET and MRI system technologies, a dedicated round table session brought together key representatives from industry and academia who were engaged with either the conceptualisation or early adoption of hybrid PET/MRI systems. Discussions during the workshop highlighted that emerging unique applications of PET/MRI such as the ability to provide multi-parametric quantitative and visual information which will enable not only overall disease detection but also disease characterisation would eventually be regarded as compelling arguments for the adoption of PET/MR. However, as indicated by previous workshops, evidence in favour of this observation is only growing slowly, mainly due to the ongoing inability to pool data cohorts from independent trials as well as different systems and sites. The participants emphasised that moving from status quo to status go entails the need to adopt standardised imaging procedures and the readiness to act together prospectively across multiple PET/MRI sites and vendors.
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2.
  • Gorgoi, M, et al. (författare)
  • The high kinetic energy photoelectron spectroscopy facility at BESSY progress and first results
  • 2009
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 601:1-2, s. 48-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Photoelectron spectroscopy at high kinetic energy is a research field that receives an increasing interest due to the possibility of studying bulk properties of materials and deeply buried interfaces. Recently the high kinetic energy electron (HIKE) spectroscopy facility at BESSY in Berlin has become operative at the bending magnet beamline KMC-1. The first results show very good performance. Electron spectra have been recorded using X-ray energies from 2 keV up to 12 keV. Using back-scattering conditions in the crystal monochromator, very high-resolution has been achieved for photon energies around 2, 6 and 8 keV. In the latter case, spectra with a resolving power from the monochromator of >= 80 000 have been achieved and it has been possible to perform electron spectroscopy with resolving power of >= 60 000, yielding a total instrument resolution of about 150 meV as determined directly from spectra. This paper describes the facility and reports some of the first results. (C) 2009 Elsevier B.V. All rights reserved.
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3.
  • Giunta, R. E., et al. (författare)
  • The COVID-19 Pandemic and its Impact on Plastic Surgery in Europe - An ESPRAS Survey
  • 2020
  • Ingår i: Handchirurgie Mikrochirurgie Plastische Chirurgie. - : Georg Thieme Verlag KG. - 0722-1819 .- 1439-3980. ; 52:3, s. 221-232
  • Tidskriftsartikel (refereegranskat)abstract
    • The present article provides an overview of the current and expected effects of plastic surgery in Europe. It presents the experience of departments for plastic and reconstructive surgery, as evaluated by interviews with members of the Executive Committee (ExCo) of the European Society of Plastic, Reconstructive and Aesthetic Surgery (ESPRAS). The objective of this overview is to summmarise current information in our area of work and to make this accessible to a broad group of readers. As our knowledge is rapidly increasing during the current pandemic, it is evident that we can only provide a snapshot and this will inevitably be incomplete.
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4.
  • Gorgoi, M., et al. (författare)
  • Hard X-ray high kinetic energy photoelectron spectroscopy at the KMC-1 beamline at BESSY
  • 2009
  • Ingår i: The European Physical Journal - Special Topics. - : Springer Science and Business Media LLC. - 1951-6355 .- 1951-6401. ; 169, s. 221-225
  • Forskningsöversikt (refereegranskat)abstract
    • Photoelectron spectroscopy at high kinetic energy is a research field that receives an increasing interest due to the possibility of studying bulk properties of materials and deeply buried interfaces. Recently, the hard x-ray high kinetic energy electron spectroscopy facility (HIKE) at BESSY in Berlin has become operative at the bending magnet beamline KMC-1. First results show excellent performance. Electron spectra have been recorded using x-ray energies continuously tunable between 2 keV and 12 keV. Using back-scattering conditions in the crystal monochromator very high resolution has been achieved for photon energies around 2 keV, 6 keV and 8 keV.
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5.
  • Gorgoi, M., et al. (författare)
  • Relative sub-shell photoionization cross-sections of nickel metal determined by hard X-ray high kinetic energy photoemission
  • 2013
  • Ingår i: Journal of Electron Spectroscopy and Related Phenomena. - : Elsevier. - 0368-2048 .- 1873-2526. ; 190, s. 153-158
  • Tidskriftsartikel (refereegranskat)abstract
    • Recently, hard X-ray high kinetic energy photoelectron spectroscopy has lead to a break-through due to its non destructive way of investigating the bulk electronic properties of materials. However, due to the relatively new development of this technique there is a lack of information concerning the photoionization cross sections at high energies. Whenever compound materials are investigated or when estimating signal levels and the feasibility of an electron spectroscopy experiment the knowledge of cross sections is essential. In the present work the experimentally determined relative sub-shell photoionization cross sections of shallow levels of nickel metal in the energy range of 2-9 keV will be shown. The data are compared with calculated sub-shell photoionization cross sections.
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6.
  • Schramm, R, et al. (författare)
  • Leukocyte adhesion in aorta and femoral artery in vivo is mediated by LFA-1
  • 2004
  • Ingår i: Inflammation Research. - : Springer Science and Business Media LLC. - 1420-908X .- 1023-3830. ; 53:10, s. 523-527
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: Cytokine-induced recruitment of leukocytes is an early feature during arterial injury and atherosclerotic plaque formation. The aim of this study was to analyze the role of the beta(2)-integrin lymphocyte function-associated antigen-1 (LFA- 1; CD11a/CD18) in cytokine-triggered firm leukocyte adhesion to arterial endothelium in vivo. Material and Methods: Intravital fluorescence microscopy was used to study leukocyte firm adhesion in the mouse aorta and femoral artery in response to combined local challenge with TNF-alpha and IL-1beta. Results: In wild-type (WT) mice, cytokine stimulation resulted in firm adhesion of 14.6 +/- 2.8 and 11.3 +/- 1.3 leukocytes/mm along the endothelium in the aorta and femoral artery (P < 0.05 vs. PBS-treated controls, n = 5-6). Notably, the number of firmly adherent leukocytes in aorta and femoral artery of cytokine-stimulated LFA-1-deficient animals was reduced by 54% and 92% indicating an important role of LFA-1 in leukocyte adhesion to arterial endothelium (P < 0.05 vs. controls, n = 5-6). In addition, pretreatment of WT mice with a monoclonal antibody (mAb) directed against murine LFA-1 attenuated the leukocyte adhesive response by 60% and 86% in aorta and femoral artery, respectively (P < 0.05 vs. control mAb-treated WT, n = 5-12). Conclusion: These novel data demonstrate that cytokine-induced firm leukocyte adhesion in the mouse aorta and femoral artery is LFA-1-dependent in vivo, which may implicate an important role for this β(2)-integrin leukocyte extravasation. in arterial injury and atherogenesis.
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  • Resultat 1-6 av 6

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