| 1. |
|
|
| 2. |
|
|
| 3. |
- Schwank, S. E., et al.
(författare)
-
Care-seeking behavior and disclosure on self-reported mental health among young women in urban Shanghai, China
- 2020
-
Ingår i: Health Psychology Open. - : SAGE Publications. - 2055-1029. ; 7:1
-
Tidskriftsartikel (refereegranskat)abstract
- Mental health is a major public health concern in China. Help-seeking behavior typically does not involve professionals. Aim of the study was to assess Shanghai women's care-seeking behavior for common mental health disorders. Using an online survey, fielding questions regarding perinatal mental health status and help-seeking behavior. A total of 487 women participated. One fifth of participants reporting badwell-being did not seek help for mental distress. A total of 82.2percent seek online support. A majority entrusted in family and avoided professional contact. Mother-in-laws were the least trusted source of support. Shanghai women avoid seeking professional help for mental health issues. Friends, spouses, and online resources are preferred venues.
|
|
| 4. |
- Esser, Sarah P., et al.
(författare)
-
A predicted CRISPR-mediated symbiosis between uncultivated archaea
- 2023
-
Ingår i: Nature Microbiology. - : Nature Publishing Group. - 2058-5276. ; 8, s. 1619-1633
-
Tidskriftsartikel (refereegranskat)abstract
- CRISPR spacers in DPANN archaea target putative essential genes in their episymbionts and could be a widespread occurrence across diverse archaeal lineages. CRISPR-Cas systems defend prokaryotic cells from invasive DNA of viruses, plasmids and other mobile genetic elements. Here, we show using metagenomics, metatranscriptomics and single-cell genomics that CRISPR systems of widespread, uncultivated archaea can also target chromosomal DNA of archaeal episymbionts of the DPANN superphylum. Using meta-omics datasets from Crystal Geyser and Horonobe Underground Research Laboratory, we find that CRISPR spacers of the hosts Candidatus Altiarchaeum crystalense and Ca. A. horonobense, respectively, match putative essential genes in their episymbionts' genomes of the genus Ca. Huberiarchaeum and that some of these spacers are expressed in situ. Metabolic interaction modelling also reveals complementation between host-episymbiont systems, on the basis of which we propose that episymbionts are either parasitic or mutualistic depending on the genotype of the host. By expanding our analysis to 7,012 archaeal genomes, we suggest that CRISPR-Cas targeting of genomes associated with symbiotic archaea evolved independently in various archaeal lineages.
|
|
| 5. |
- Favre, G, et al.
(författare)
-
Mental health in pregnant individuals during the COVID-19 pandemic based on a Swiss online survey
- 2022
-
Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 12:1, s. 18448-
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of our study was to evaluate the mental health of pregnant individuals during the early COVID-19 pandemic and the potential factors associated. A Swiss online survey was proposed to individuals who gave birth during the pandemic period from March 2020. The Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder 7 questions (GAD-7), and Impact Event Scale-Revised (IES-R) were evaluated and used to defined mental health impairment as a composite outcome. From October, 2020 to February, 2021, 736 participants responded. The anxiety GAD-7 score was moderate in 9.6% and severe in 2.0%. The EPDS was moderate in 21.5% and severe in 32.9%. The IES-R was moderate in 10.3% and severe in 3.9%. Mental health impairment was reported in 37.0%. The association between the risk of mental health impairment and foreign nationality was significant (OR = 1.48; 95%CI [1.06–2.05]) as well as fetal and pregnancy worries because of coronavirus (OR = 1.46; 95% CI [1.08–1.98]) and 1.65; 95% CI [1.22–2.24]). Adjusted ORs were significant for foreign nationality (aOR = 1.51; 95%CI [1.07–2.13]) and pregnancy worries because of coronavirus (aOR = 1.62; 95%CI [1.10–2.40]). Pregnant people and especially foreign national have a high risk of mental health impairment during the pandemic.
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
|
|
