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Sökning: WFRF:(Selkrig J)

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1.
  • Lahiri, S, et al. (författare)
  • The gut microbiota influences skeletal muscle mass and function in mice
  • 2019
  • Ingår i: Science translational medicine. - : American Association for the Advancement of Science (AAAS). - 1946-6242 .- 1946-6234. ; 11:502
  • Tidskriftsartikel (refereegranskat)abstract
    • Transplanting the gut microbiota of pathogen-free mice into germ-free mice improves skeletal muscle mass and strength.
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2.
  • Selkrig, J, et al. (författare)
  • The Drosophila microbiome has a limited influence on sleep, activity, and courtship behaviors
  • 2018
  • Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 10646-
  • Tidskriftsartikel (refereegranskat)abstract
    • In animals, commensal microbes modulate various physiological functions, including behavior. While microbiota exposure is required for normal behavior in mammals, it is not known how widely this dependency is present in other animal species. We proposed the hypothesis that the microbiome has a major influence on the behavior of the vinegar fly (Drosophila melanogaster), a major invertebrate model organism. Several assays were used to test the contribution of the microbiome on some well-characterized behaviors: defensive behavior, sleep, locomotion, and courtship in microbe-bearing, control flies and two generations of germ-free animals. None of the behaviors were largely influenced by the absence of a microbiome, and the small or moderate effects were not generalizable between replicates and/or generations. These results refute the hypothesis, indicating that the Drosophila microbiome does not have a major influence over several behaviors fundamental to the animal’s survival and reproduction. The impact of commensal microbes on animal behaviour may not be broadly conserved.
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