| 1. |
- Purnomo, Kartiko Arif, et al.
(författare)
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Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities
- 2021
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Ingår i: Journal of Agricultural and Food Chemistry. - : American Chemical Society (ACS). - 0021-8561 .- 1520-5118. ; 69:40, s. 11856-11866
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Tidskriftsartikel (refereegranskat)abstract
- Four active partition layers and ten isolates, including (5R)- and (5S)-macapyrrolidone A (1a, 1b), and four new alkaloids, (5R)- and (5S)-macapyrrolidone B (2a, 2b) and macapyrrolins D, E (3, 4), were isolated from maca (Lepidium meyenii Walp.), an indigenous food plant from Peru. Derived from the n-hexane layer, the macamide-rich fraction exhibited pro-angiogenic activity on EPC and HUVEC cells. Anti-thrombotic activity was displayed by the polar part of maca extracts (n-butanol and water layers). Both 75% methanol aq. (midlower polar part) and n-hexane (low polar part) layers, which showed signs of fatty acid content, markedly inhibited superoxide and elastase release in an anti-inflammatory assay. The 75% methanol aq. layer showed strong anti-allergic activity, and macapyrrolin A (5) was found active based on beta-hexosaminidase release inhibition assays and a ChemGPS-NP experiment. These valuable bioactivity results suggest that maca is a food plant with good benefits for human health.
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| 2. |
- Shih, Hsuan-Chang, et al.
(författare)
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High-resolution gravity and geoid models in Tahiti obtained from new airborne and land gravity observations: data fusion by spectral combination
- 2015
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Ingår i: Earth, Planets and Space. - : Springer Science and Business Media LLC. - 1880-5981 .- 1343-8832. ; 67
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Tidskriftsartikel (refereegranskat)abstract
- For the first time, we carry out an airborne gravity survey and we collect new land gravity data over the islands of Tahiti and Moorea in French Polynesia located in the South Pacific Ocean. The new land gravity data are registered with GPS-derived coordinates, network-adjusted and outlier-edited, resulting in a mean standard error of 17 μGal. A crossover analysis of the airborne gravity data indicates a mean gravity accuracy of 1.7 mGal. New marine gravity around the two islands is derived from Geosat/GM, ERS-1/GM, Jason-1/GM, and Cryosat-2 altimeter data. A new 1-s digital topography model is constructed and is used to compute the topographic gravitational effects. To use EGM08 over Tahiti and Moorea, the optimal degree of spherical harmonic expansion is 1500. The fusion of the gravity datasets is made by the band-limited least-squares collocation, which best integrates datasets of different accuracies and spatial resolutions. The new high-resolution gravity and geoid grids are constructed on a 9-s grid. Assessments of the grids by measurements of ground gravity and geometric geoidal height result in RMS differences of 0.9 mGal and 0.4 cm, respectively. The geoid model allows 1-cm orthometric height determination by GPS and Lidar and yields a consistent height datum for Tahiti and Moorea. The new Bouguer anomalies show gravity highs and lows in the centers and land-sea zones of the two islands, allowing further studies of the density structure and volcanism in the region.
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