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- Bai, Xuemei, et al.
(författare)
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Defining and advancing a systems approach for sustainable cities
- 2016
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Ingår i: Current Opinion in Environmental Sustainability. - : Elsevier BV. - 1877-3435 .- 1877-3443. ; 23, s. 69-78
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Forskningsöversikt (refereegranskat)abstract
- The sustainable development of cities is increasingly recognized as crucial to meeting collectively agreed sustainability goals at local, regional and global scales, and more broadly to securing human well-being worldwide. The UN Sustainable Development Goals (SDGs) include a goal on cities (Goal 11), with most other goals and targets have urban applications and multi scalar implications for their implementation. Further, the interdependencies - including synergies and trade-offs among the various SDGs are greater in cities, presenting both challenges and opportunities. A systems approach is urgently needed in urban research and policy analysis, but such an approach rarely features in current analysis or urban decision-making for various reasons. This paper explores four questions: why a systems approach is necessary, what defines such an approach, why has this rarely been adopted in practice, and what can be done to promote its use. We argue that a systems approach can reveal unrecognized opportunities to maximize co-benefits and synergies, guide management of inevitable trade-offs, and therefore inform prioritisation and successful solutions. We present four key issues for the effective implementation of the SDGs and the New Urban Agenda, which emerged from UN Habitat III Conference, namely: (a) a radical redesign of the multilateral institutional setup on urban issues; (b) promoting regenerative culture, behaviour, and design; (c) exploring ways to finance a systems approach; and (d) a new and enhanced role for science in sustainable development. The latter issue could be addressed through Future Earth's Urban Knowledge-Action Network, which aims at co-designing and co-producing cutting-edge and actionable knowledge for sustainable cities bringing together researchers and urban decision-makers and practitioners.
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- Shrivastava, Garima, et al.
(författare)
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Targeting LIN28 : a new hope in prostate cancer theranostics
- 2021
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Ingår i: Future Oncology. - : Future Medicine. - 1479-6694 .- 1744-8301. ; 17:29, s. 3873-3880
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Tidskriftsartikel (refereegranskat)abstract
- The mortality and morbidity rates for prostate cancer have recently increased to alarming levels, rising higher than lung cancer. Due to a lack of drug targets and molecular probes, existing theranostic techniques are limited. Human LIN28A and its paralog LIN28B overexpression are associated with a number of tumors resulting in a remarkable increase in cancer aggression and poor prognoses. The current review aims to highlight recent work identifying the key roles of LIN28A and LIN28B in prostate cancer, and to instigate further preclinical and clinical research in this important area.
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- Stafford-Smith, Mark, et al.
(författare)
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Integration : the key to implementing the Sustainable Development Goals
- 2017
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Ingår i: Sustainability Science. - : Springer Science and Business Media LLC. - 1862-4065 .- 1862-4057. ; 12:6, s. 911-919
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Tidskriftsartikel (refereegranskat)abstract
- On 25 September, 2015, world leaders met at the United Nations in New York, where they adopted the Sustainable Development Goals. These 17 goals and 169 targets set out an agenda for sustainable development for all nations that embraces economic growth, social inclusion, and environmental protection. Now, the agenda moves from agreeing the goals to implementing and ultimately achieving them. Across the goals, 42 targets focus on means of implementation, and the final goal, Goal 17, is entirely devoted to means of implementation. However, these implementation targets are largely silent about interlinkages and interdependencies among goals. This leaves open the possibility of perverse outcomes and unrealised synergies. We demonstrate that there must be greater attention on interlinkages in three areas: across sectors (e.g., finance, agriculture, energy, and transport), across societal actors (local authorities, government agencies, private sector, and civil society), and between and among low, medium and high income countries. Drawing on a global sustainability science and practice perspective, we provide seven recommendations to improve these interlinkages at both global and national levels, in relation to the UN's categories of means of implementation: finance, technology, capacity building, trade, policy coherence, partnerships, and, finally, data, monitoring and accountability.
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