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Sökning: WFRF:(Siamak S.)

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1.
  • Abbafati, Cristiana, et al. (författare)
  • 2020
  • Tidskriftsartikel (refereegranskat)
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2.
  • Kulka, U., et al. (författare)
  • Realising the European network of biodosimetry : RENEB-status quo
  • 2015
  • Ingår i: Radiation Protection Dosimetry. - : Oxford University Press (OUP). - 0144-8420 .- 1742-3406. ; 164:1-2, s. 42-45
  • Tidskriftsartikel (refereegranskat)abstract
    • Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well-organised cooperative action involving EU laboratories will offer the best chance for fast and trustworthy dose assessments that are urgently needed in an emergency situation. To this end, the EC supports the establishment of a European network in biological dosimetry (RENEB). The RENEB project started in January 2012 involving cooperation of 23 organisations from 16 European countries. The purpose of RENEB is to increase the biodosimetry capacities in case of large-scale radiological emergency scenarios. The progress of the project since its inception is presented, comprising the consolidation process of the network with its operational platform, intercomparison exercises, training activities, proceedings in quality assurance and horizon scanning for new methods and partners. Additionally, the benefit of the network for the radiation research community as a whole is addressed.
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3.
  • Barregård, Lars, 1948, et al. (författare)
  • Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2 '-deoxyguanosine
  • 2013
  • Ingår i: Antioxidants and Redox Signaling. - : Mary Ann Liebert Inc. - 1523-0864 .- 1557-7716. ; 18:18, s. 2377-2391
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) is a widely used biomarker of oxidative stress. However, variability between chromatographic and ELISA methods hampers interpretation of data, and this variability may increase should urine composition differ between individuals, leading to assay interference. Furthermore, optimal urine sampling conditions are not well defined. We performed inter-laboratory comparisons of 8-oxodG measurement between mass spectrometric-, electrochemical- and ELISA-based methods, using common within-technique calibrants to analyze 8-oxodG-spiked phosphate-buffered saline and urine samples. We also investigated human subject- and sample collection-related variables, as potential sources of variability. Results: Chromatographic assays showed high agreement across urines from different subjects, whereas ELISAs showed far more inter-laboratory variation and generally overestimated levels, compared to the chromatographic assays. Excretion rates in timed 'spot' samples showed strong correlations with 24 h excretion (the 'gold' standard) of urinary 8-oxodG (r(p) 0.67-0.90), although the associations were weaker for 8-oxodG adjusted for creatinine or specific gravity (SG). The within-individual excretion of 8-oxodG varied only moderately between days (CV 17% for 24 h excretion and 20% for first void, creatinine-corrected samples). Innovation: This is the first comprehensive study of both human and methodological factors influencing 8-oxodG measurement, providing key information for future studies with this important biomarker. Conclusion: ELISA variability is greater than chromatographic assay variability, and cannot determine absolute levels of 8-oxodG. Use of standardized calibrants greatly improves intra-technique agreement and, for the chromatographic assays, importantly allows integration of results for pooled analyses. If 24 h samples are not feasible, creatinine- or SG-adjusted first morning samples are recommended.
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4.
  • Kazemi, E., et al. (författare)
  • The effect of superposition of 900 MHz and incoherent noise electromagnetic fields on the induction of reactive oxygen species in SP2/0 cell line
  • 2015
  • Ingår i: International journal of radiation research. - 2322-3243. ; 13:3, s. 275-280
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Induction of cellular response after exposure to electromagnetic fields is limited to coherent fields. An incoherent noise field is supposed to suppress the bioeffects of regular RF electromagnetic fields. The purpose of this study was to investigate the effect of GSM mobile phone-induced radiofrequency (RF) on the induction of oxidative stress in SP2/0 cell line. Materials and Methods: This study was also an attempt to assess whether these RF-induced effects can be blocked by superposing the RF radiation and an incoherent magnetic noise. Three groups of cultured cells were used in this study. The cells in the first group were only exposed to RF radiation emitted from a mobile phone simulator. The second group was only exposed to an incoherent noise field and the third group was simultaneously exposed to RF radiation and incoherent noise field. The exposure duration in all groups was 2 hours. The level of ROS production in the cells was quantified by the CM-H2DCFDA fluorescence probe, using flow cytometry technique. Results: Although our results showed increased ROS production after exposure to 900 MHz RF radiation, superposition of 900 MHz RF and the incoherent noise fields did not lead to increased levels of ROS in any experiment. However, the differences between RF exposure group and superposition of RF and noise exposure group were not statistically significant. Conclusion: Altogether our results cannot support the neutralizing effect of noise theory but may confirm the concept that just the coherent fields can be bioeffective while the incoherent noise fields cannot cause any biological effects.
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5.
  • Kulka, U., et al. (författare)
  • Realising the European Network of Biodosimetry (RENEB)
  • 2012
  • Ingår i: Radiation Protection Dosimetry. - : Oxford University Press (OUP). - 0144-8420 .- 1742-3406. ; 151:4, s. 621-625
  • Tidskriftsartikel (refereegranskat)abstract
    • In Europe, a network for biological dosimetry has been created to strengthen the emergency preparedness and response capabilities in case of a large-scale nuclear accident or radiological emergency. Through the RENEB (Realising the European Network of Biodosimetry) project, 23 experienced laboratories from 16 European countries will establish a sustainable network for rapid, comprehensive and standardised biodosimetry provision that would be urgently required in an emergency situation on European ground. The foundation of the network is formed by five main pillars: (1) the ad hoc operational basis, (2) a basis of future developments, (3) an effective quality-management system, (4) arrangements to guarantee long-term sustainability and (5) awareness of the existence of RENEB. RENEB will thus provide a mechanism for quick, efficient and reliable support within the European radiation emergency management. The scientific basis of RENEB will concurrently contribute to increased safety in the field of radiation protection.
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7.
  • Contemporary Muslim Travel Cultures : Practices, Complexities and Emerging Issues
  • 2022
  • Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
    • This timely volume brings together various issues in Muslim consumer cultures and provides a comprehensive account of Muslim tourism and tourist behaviour. Islam is a major international religion and Muslims are a majority of the population in many countries in Asia, the Middle East and North Africa. The growth of a substantial middle class, the development of Islamic consumer cultures, rising Muslim market consumption in non-Muslim majority destinations and the growing significance of intra-Muslim traffic and rising outbound tourism expenditure in emerging Muslim markets have all contributed to substantial interest in Muslim tourism. However, travel by Muslims is about far more than the Hajj and Umrah, as important as they are as acts of devotion. Instead, although often portrayed in the West as a monolithic religion, Muslim travel and leisure behaviour is very diverse, with different traditions and cultures leading to a range of expressions of tourism-related consumption culture and practices. Drawing on a range of empirical studies undertaken in different social and economic contexts and countries, this book provides a well-balanced portrayal of the Muslim tourism experience and practices. This book makes a substantial contribution to an improved understanding of Muslim travel culture and will be required reading for anyone interested in this fast-growing market.
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10.
  • Hall, C. Michael, et al. (författare)
  • Muslim travel cultures : Introduction and context
  • 2022
  • Ingår i: Contemporary Muslim Travel Cultures. - London : Routledge. - 9781000625868 - 9780367477400 - 9781003036296
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Travel is an essential element of Islamic spirituality. However, in modernity, notions of what constitutes Islamic travel and recreation has expanded and Islamic travel culture has arguably gone through the same challenges as broader Islam with respect to the sacred and the profane and the relationship to modern consumerism. Islamic knowledge, performances and identities are increasingly being contrasted through material commodities and consumption practices, such as tourism and travel, and which reflect the emergence of halal, Muslim-friendly and other Islamic tourisms as a product category. This first chapter provides an introduction to the book. It first discusses the role of travel in Islam before examining some of the definitional issues involved in Muslim travel and the implications that this has for research. It then touches on some of the issues involved in undertaking research on tourism and Islam before providing an outline of the book. © 2023 selection and editorial matter, C. Michael Hall, Siamak Seyfi and S. Mostafa Rasoolimanesh.
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