| 1. |
- Aad, G., et al.
(författare)
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- 2011
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swepub:Mat__t (refereegranskat)
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| 2. |
- Schael, S., et al.
(författare)
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Electroweak measurements in electron positron collisions at W-boson-pair energies at LEP
- 2013
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Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 532:4, s. 119-244
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Forskningsöversikt (refereegranskat)abstract
- Electroweak measurements performed with data taken at the electron positron collider LEP at CERN from 1995 to 2000 are reported. The combined data set considered in this report corresponds to a total luminosity of about 3 fb(-1) collected by the four LEP experiments ALEPH, DELPHI, 13 and OPAL, at centre-of-mass energies ranging from 130 GeV to 209 GeV. Combining the published results of the four LEP experiments, the measurements include total and differential cross-sections in photon-pair, fermion-pair and four-fermion production, the latter resulting from both double-resonant WW and ZZ production as well as singly resonant production. Total and differential cross-sections are measured precisely, providing a stringent test of the Standard Model at centre-of-mass energies never explored before in electron positron collisions. Final-state interaction effects in four-fermion production, such as those arising from colour reconnection and Bose Einstein correlations between the two W decay systems arising in WW production, are searched for and upper limits on the strength of possible effects are obtained. The data are used to determine fundamental properties of the W boson and the electroweak theory. Among others, the mass and width of the W boson, m(w) and Gamma(w), the branching fraction of W decays to hadrons, B(W -> had), and the trilinear gauge-boson self-couplings g(1)(Z), K-gamma and lambda(gamma), are determined to be: m(w) = 80.376 +/- 0.033 GeV Gamma(w) = 2.195 +/- 0.083 GeV B(W -> had) = 67.41 +/- 0.27% g(1)(Z) = 0.984(-0.020)(+0.018) K-gamma - 0.982 +/- 0.042 lambda(gamma) = 0.022 +/- 0.019. (C) 2013 Elsevier B.V. All rights reserved.
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| 3. |
- Abdallah, J., et al.
(författare)
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A measurement of the tau hadronic branching ratios
- 2006
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:1, s. 1-26
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Tidskriftsartikel (refereegranskat)abstract
- The exclusive and semi-exclusive branching ratios of the tau lepton hadronic decay modes (h(-)upsilon(tau), h(-)pi(0)upsilon(tau), h(-)pi(0)pi(0)upsilon(tau), h(-) >= 2 pi(0)nu(tau), 2h(-)h(+)upsilon(tau), 2h(-)h(+)>= 2 pi(0)upsilon(tau), 3h(-)2h(+)upsilon(tau) and 3h(-)2h(+) >= 1 pi(0)upsilon(tau)) were measured with data from the DELPHI detector at LEP.
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| 4. |
- Claeys, Shana, et al.
(författare)
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ALK positively regulates MYCN activity through repression of HBP1 expression
- 2019
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Ingår i: Oncogene. - : Springer Science and Business Media LLC. - 0950-9232 .- 1476-5594. ; 38:15, s. 2690-2705
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Tidskriftsartikel (refereegranskat)abstract
- ALK mutations occur in 10% of primary neuroblastomas and represent a major target for precision treatment. In combination with MYCN amplification, ALK mutations infer an ultra-high-risk phenotype resulting in very poor patient prognosis. To open up opportunities for future precision drugging, a deeper understanding of the molecular consequences of constitutive ALK signaling and its relationship to MYCN activity in this aggressive pediatric tumor entity will be essential. We show that mutant ALK downregulates the ‘HMG-box transcription factor 1’ (HBP1) through the PI3K-AKT–FOXO3a signaling axis. HBP1 inhibits both the transcriptional activating and repressing activity of MYCN, the latter being mediated through PRC2 activity. HBP1 itself is under negative control of MYCN through miR-17~92. Combined targeting of HBP1 by PI3K antagonists and MYCN signaling by BET- or HDAC-inhibitors blocks MYCN activity and significantly reduces tumor growth, suggesting a novel targeted therapy option for high-risk neuroblastoma.
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| 5. |
- Jolis, Ester M., et al.
(författare)
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Skarn xenolith record crustal CO2 liberation during Pompeii and Pollena eruptions, Vesuvius volcanic system, central Italy
- 2015
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Ingår i: Chemical Geology. - : Elsevier BV. - 0009-2541 .- 1872-6836. ; 415, s. 17-36
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Tidskriftsartikel (refereegranskat)abstract
- Limestone assimilation and skarn formation are important processes in magmatic systems emplaced within carbonate-rich crust and can affect the composition of the magma and that of associated volcanic gas. In this study we focus on marble and calc-silicate (skarn) xenoliths from contact reactions between magma and carbonate wall-rock of the Vesuvius volcanic system. We present new elemental and C-O isotope data for marble and skarn xenoliths as well as for igneous rocks collected from the AD 79 (Pompeii) and AD 472 (Pollena) eruptions. The igneous samples have consistently high delta O-18 values (9.3 to 10.8 parts per thousand), but low H2O contents (<= 1.5%), indicating that magma-crust interaction prior to eruption took place. The marble xenoliths, in turn, record initial decarbonation reactions and fluid-mass exchange in their textures and delta C-13 and delta O-18 ranges, while the skarn xenoliths reflect prolonged magma-carbonate interaction and intense contact metamorphism. Skarn-xenoliths record Ca and Mg release from the original carbonate and uptake of Al and Si and span the full delta O-18 data range from unmetamorphosed carbonate (>18 parts per thousand) to values typical for Vesuvius magmatic rocks (similar to 7.5 parts per thousand), which implies that skarn xenoliths comprise carbonate and magmatic components. Textural and chemical evidence suggest that direct carbonate dissolution into the host magmas occurred as well as post-metamorphic skarn recycling, resulting in progressive Ca and Mg liberation from the skarn xenoliths into the magma. Magma-carbonate interaction is an additional source of CO2 during carbonate break-down and assimilation and we calculate the amount of extra volatile components likely liberated by contact metamorphic reactions before and during the investigated eruptions. We find that the extra CO2 added into the volcanic system could have outweighed the magmatic CO2 component by >= factor seven and thus likely increased the intensity of both the Pompeii and the Pollena eruptive events.
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| 6. |
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