| 1. |
- Eriksson, Mikael, et al.
(författare)
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MAX-IV Design: Pushing the Envelope
- 2007
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Ingår i: 2007 IEEE Particle Accelerator Conference, vols 1-11. - 9781424409167 ; , s. 1277-1279
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Konferensbidrag (refereegranskat)abstract
- The proposed MAX IV facility is meant as a successor to the existing MAX-lab. The accelerator part will consist of three storage rings, two new ones operated at 3 and 1.5 GeV respectively and the existing 700 MeV MAX III ring. The two new rings have identical lattices and are placed on top of each other. Both these rings have a very small emittance, 0.86 and 0.4 nm rad respectively, and offer synchrotron radiation of very high mean brilliance. As an injector, a 3 GeV linear accelerator is planned. The design philosophy and the special technical solutions called for are presented in this paper.
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| 2. |
- Eriksson, Mikael, et al.
(författare)
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STATUS OF THE MAX IV LIGHT SOURCE PROJECT
- 2006
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Ingår i: European Particle Accelerator Conference 2006, Edinburgh, UK.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 3. |
- Malmgren, Linnea, et al.
(författare)
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The complexity of kidney disease and diagnosing it - Cystatin C, selective glomerular hypofiltration syndromes and proteome regulation.
- 2023
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Ingår i: Journal of Internal Medicine. - : John Wiley & Sons. - 0954-6820 .- 1365-2796. ; 293:3, s. 293-308
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Tidskriftsartikel (refereegranskat)abstract
- Estimation of kidney function is often part of daily clinical practice, mostly done by using the endogenous GFR-markers creatinine or cystatin C. A recommendation to use both markers in parallel in 2010 has resulted in new knowledge concerning the pathophysiology of kidney disorders by identification of a new set of kidney disorders, selective glomerular hypofiltration syndromes. These syndromes, connected to strong increases in mortality and morbidity, are characterised by a selective reduction in the glomerular filtration of 5-30 kDa molecules, such as cystatin C, compared to the filtration of small molecules < 1kDa dominating the glomerular filtrate e.g., water, urea, creatinine. At least two types of such disorders, shrunken or elongated pore syndrome, are possible according to the pore model for glomerular filtration. Selective glomerular hypofiltration syndromes are prevalent in investigated populations, and patients with these syndromes often display normal measured GFR or creatinine-based GFR-estimates. The syndromes are characterised by proteomic changes promoting the development of atherosclerosis, indicating antibodies and specific receptor-blocking substances as possible new treatment modalities. Presently, the KDIGO guidelines for diagnosing kidney disorders do not recommend cystatin C as a general marker of kidney function and will therefore not allow the identification of a considerable number of patients with selective glomerular hypofiltration syndromes. Furthermore, as cystatin C is uninfluenced by muscle mass, diet or variations in tubular secretion and cystatin C-based GFR-estimation equations do not require controversial race or sex terms, it is obvious that cystatin C should be a part of future KDIGO guidelines.
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| 4. |
- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 5. |
- Sjöström, Mattias, et al.
(författare)
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A job-exposure matrix for occupational noise : development and validation.
- 2013
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Ingår i: Annals of Occupational Hygiene. - : Oxford University Press (OUP). - 0003-4878 .- 1475-3162. ; 57:6, s. 774-83
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To develop a job-exposure matrix (JEM) for occupational noise in Sweden and to estimate its validity.METHODS: The JEM, developed by a group of experienced occupational hygienists, contains 321 job families with information regarding occupational noise from 1970 to 2004. The occupational noise information derives from measurements collected from different sources. The time period label has a 5-year scale starting in 1970. The estimated average 8h (TWA) noise level in decibel [dB(A)] for every 5-year period was coded either as <75 dB(A), 75-84 dB(A), or ≥85 dB(A) and the risk of peak level exposure assessed. The validity of the JEM is tested, using Svensson's non-parametric methods based on classification consensus, reached by a second group of occupational hygienists.RESULTS/DISCUSSION: Validation results show ~ 80% agreement and no systematic differences, in classification, between the two different groups of occupational hygienists, classifying the occupational noise exposure. However, classification of peak level exposure did show a systematic difference in relative position. The results will give more power to the JEM that it gives a good general estimate for the occupational noise levels in Sweden for different job families during 1970-2004. We, thus, intend to use it in further studies and also make it available to collaborators.
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| 6. |
- Wallén, Erik, et al.
(författare)
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Status of the MAX IV light source project
- 2007
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Ingår i: 9th International Conference on Synchrotron Radiation Instrumentation (SRI 2006). - 9780735403734 ; 879, s. 34-37
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Konferensbidrag (refereegranskat)abstract
- The MAX IV light source project is presented. The MAX IV light source will consist of three low emittance storage rings and a 3 GeV injector linac. The three storage rings will be operated at 700 MeV, 1.5 GeV, and 3.0 GeV, which make it possible to cover a large spectral range from IR to hard X-rays with high brilliance undulator radiation from insertion devices optimised for each storage ring. The preparation of the injector linac to serve as a short pulse source and the major sub-systems of the facility are also presented.
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| 7. |
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| 8. |
- Alm, Stina, et al.
(författare)
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Erythrocyte transfusions increased the risk of elevated serum ferritin in very low birth weight infants and were associated with altered longitudinal growth
- 2020
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Ingår i: Acta Paediatrica. - : John Wiley & Sons. - 0803-5253 .- 1651-2227. ; 109:7, s. 1354-1360
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Tidskriftsartikel (refereegranskat)abstract
- Aim: There has been a lack of population‐based longitudinal data on serum ferritin in very low birth weight (VLBW) infants during hospitalisation. Our aim was to fill this gap in the knowledge and investigate risk factors for elevated serum ferritin and associations between erythrocyte transfusions and longitudinal growth.Methods: We retrospectively reviewed longitudinal data on 126 VLBW infants treated at Umeå University Hospital, Sweden, between 2010‐2013.Results: The infants’ mean gestational age and birth weight were 26.9 weeks and 899 grams. Most (91%) received erythrocyte transfusions and the majority had multiple erythrocyte transfusions. There was a significant correlation between serum ferritin and the volume of transfusions. Almost two‐thirds had at least one serum ferritin measurement of more than 350 µg/L, indicating iron overload. In those with complete anthropometric data (n=78) there was no significant effect of serum ferritin concentrations in relation to longitudinal growth, but there was a positive association between the erythrocyte transfusion dose and longitudinal growth in VLBW infants born before 25 weeks.Conclusion: This is the first population‐based study to investigate longitudinal data on serum ferritin in VLBW infants during hospitalisation. The unexpected positive finding in the subgroup born at less than 25 weeks needs further research with a larger cohort.
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| 9. |
- Alm, Stina, et al.
(författare)
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Prevalence and risk factors for post discharge feeding problems in children born extremely preterm
- 2023
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Ingår i: Journal of Pediatric Gastroenterology and Nutrition - JPGN. - : Wolters Kluwer. - 0277-2116 .- 1536-4801. ; 76:4, s. 498-504
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Preterm infants have a high risk of post discharge feeding problems, but there is a lack of population-based studies in infants born extremely preterm and little is known about underlying mechanisms.The objectives were to assess the incidence of post discharge feeding problems and underweight in a population-based cohort of infants born extremely preterm in Sweden (EXPRESS) and identify perinatal risk factors.Methods: Perinatal health data and prenatal/postnatal growth data was prospectively collected in the cohort. Data on clinical diagnoses related to feeding problems were obtained from the Swedish Patient Register, population prevalence data was also obtained. The main outcome was a composite of post discharge feeding problem diagnosis and/or underweight at 2.5 years of age.Results: In total, 66 children (19%) had post discharge feeding problems diagnosed before 2 years and/or underweight at 2.5 years of age. The risk of feeding problems when compared to the general population was significantly higher, with an odds ratio (OR) of 193 (95% CI 137.6-270.9). The strongest risk factors for feeding problems were the number of days on mechanical ventilation during the first eight postnatal weeks, OR of 1.59 (CI 95% 1.29-1.98), and the Clinical Risk Index for Babies-score, OR of 1.14 (CI 95% 1.03-1.26).Conclusions: Post discharge feeding problems and underweight are common in children born extremely preterm. The strongest perinatal risk factor for later feeding problems was early treatment with mechanical ventilation. Identifying infants at risk of post discharge feeding problems might be useful for targeting of nutritional support.
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| 10. |
- Almlöf, Erik, 1985-
(författare)
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Slutrapport - Självkörande fullängdsbuss på Tvärförbindelse Södertörn
- 2021
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Rapport (populärvet., debatt m.m.)abstract
- Föreliggande slutrapport är finansierad av Trafikverkets FoI portfölj, strategiska initiativ,för projekt Självkörande eldriven stombuss på Tvärförbindelse Södertörn – En skalbarfallstudie (TRV 2019/118695). Partners i projektet är Trafikverket, Scania, Volvo, Keolis,KTH samt Sweco där även Trafikförvaltningen Region Stockholm, Nobina och projektTvärförbindelse Södertörn har bidragit till arbetet som pågått från maj 2020 till mars 2021.Ansvarig för projektet inom Trafikverket har varit Stora projekt.För att skapa en förståelse för konsekvenser av tekniska utveckling i relation tillnödvändiga fysiska och digitala åtgärder har tre scenarier tagits fram: Bus Driver Plus,Automation with Adaption och Automation Utopia. Dessa scenarier beskriver olika nivåerav automation och behov av kringliggande stödsystem. I det första scenario finns enförare ombord på bussen som tar över körningen vid farliga situationer. Det andrascenariot avser en självkörande buss utan förare där den fysiska infrastrukturen haranpassats genom ett införande av ett eget busskörfält. Det sista scenariot beskriver enframtid där bussen helt förlitar sig på digital teknik och en operatör kontrollerar körningenav flera fordon från ett avsides kontrolltorn.De tre scenarierna utvärderades genom en samlad effektbedömning, Trafikverkets metodför att utvärdera åtgärder. Resultaten visar att den största vinsten av automatisering kanhandla om resenärernas bekvämlighet och inte nödvändigtvis om att minimera kostnaderför förare. Antaganden om att resenärerna kan uppleva resan bekvämare är troligtvisöverskattade, men resultaten visar att även små förbättringar i bekvämlighet kan ge storasamhälleliga vinster.Scenariot där bussen har ett eget körfält innebär mycket stora kostnader och är troligtvisinte ekonomiskt försvarbart. Dessutom kommer enbart en busslinje att trafikeramotorleden som dessutom består av 3 tunnlar. Vidare är det inte säkert att den aktör somgör nödvändiga investeringar är den aktör som får ta del av de samhälleliga vinsterna. Iscenariot skulle Trafikverket stå för stora delar av investeringskostnaden, medan vinsten för personalbesparingar uppstår för Region Stockholm och kollektivtrafikresenärerna somåker längs sträckan.Projektet har även undersökt hur multimodala hubbar (nod som möjliggör smidigt bytemellan olika transportmedel) längs med förbindelsen kan stödja eldrivna och självkörandebussar. Det är viktigt att ny väginfrastruktur bidrar till en attraktiv kollektivtrafik därresenärer i första hand väljer buss istället för bil. För att eldrivna och självkörande bussarska införas behöver Region Stockholm ställa nya krav i upphandlingar för attåstadkomma en förändring i transportsystemet. Nya krav som skapar ekonomiskaincitament för operatörer som utför den operativa verksamheten över lång tid. Det är dockproblematiskt att ställa krav på eldrift eftersom det saknas tillgänglig infrastruktur iStockholm.Avseende självkörande fullängdsbussar är tekniken helt enkelt inte tillräckligt mogen idag.Dock tror många experter att självkörande bussar kommer att införas, både i stadsmiljöoch glesbygd, när tekniken och samhället är redo för det, gissningsvis kring år 2030.
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