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Numrering	Referens	Omslagsbild	Hitta
1.	Bousquet, J, et al. (författare) Integrated care pathways for airway diseases (AIRWAYS-ICPs) 2014 Ingår i: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 44:2, s. 304-323 Tidskriftsartikel (refereegranskat)
2.	Clark, DW, et al. (författare) Associations of autozygosity with a broad range of human phenotypes 2019 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4957- Tidskriftsartikel (refereegranskat)abstract In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding.
3.	Kentistou, KA, et al. (författare) Understanding the genetic complexity of puberty timing across the allele frequency spectrum 2023 Ingår i: medRxiv : the preprint server for health sciences. Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
4.	Pedersen, NL, et al. (författare) Neuroimaging findings in twins discordant for Alzheimer's disease 1999 Ingår i: Dementia and geriatric cognitive disorders. - : S. Karger AG. - 1420-8008 .- 1421-9824. ; 10:1, s. 51-58 Tidskriftsartikel (refereegranskat)abstract Data from computed tomography (CT) scans of 12 twin pairs in which one partner had Azheimer’s disease (AD) and the other partner is cognitively intact were analyzed to study structural brain features associated with AD while controlling for familial factors. Visual ratings and analysis of quantified areas and volumes indicated that AD twins showed more dilation of temporal horns, lateral ventricles and third ventricle, and more atrophy of temporal lobes, particularly in the anterior temporal/perisylvian area, than their healthy cotwins. Demented twins did not have smaller intracranial areas or overall brain volumes than their intact partners. The apolipoprotein σ-4 allele was associated with greater dilation of lateral ventricles and ventricular volume. Significant intrapair correlations were found for total intracranial area and volume, cerebellar area and white matter lesions.
5.	Roche, N, et al. (författare) The importance of real-life research in respiratory medicine: manifesto of the Respiratory Effectiveness Group: Endorsed by the International Primary Care Respiratory Group and the World Allergy Organization 2019 Ingår i: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 54:3 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)

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Typ av publikation: tidskriftsartikel (5)

Typ av innehåll: refereegranskat (3); övrigt vetenskapligt/konstnärligt (2)

Författare/redaktör: Price, D. (2); Luan, J. (2); Pedersen, NL (2); Bousquet, J (2); Gaga, M (2); Demoly, P. (2); visa fler...; Smith, AV (2); Gudnason, V (2); Montgomery, GW (2); Martin, NG (2); Launer, LJ (2); Medland, SE (2); Agache, I (2); Haiman, CA (2); Vogelmeier, C (2); Nolte, IM (2); Timpson, NJ (2); Lawlor, DA (2); Boerwinkle, E (2); Kraft, P (2); Campbell, A (2); McCarthy, MI (2); Esko, T (2); Eriksson, JG (2); Wilson, JF (2); Wareham, NJ (2); Gieger, C (2); Stefansson, K (2); Cousminer, DL (2); Bradfield, JP (2); Hakonarson, H (2); Millwood, IY (2); Pennell, CE (2); Ong, KK (2); Lin, K (2); Karlsson, R (2); Canonica, GW (2); Gudbjartsson, DF (2); Meitinger, T (2); Kamatani, Y (2); Hayward, C. (2); Kolcic, I. (2); Polašek, O. (2); Nyholt, DR (2); Joshi, PK (2); Vitart, V (2); Roche, N (2); Broer, L (2); Chasman, DI (2); Turman, C (2); visa färre...

Lärosäte: Karolinska Institutet (5); Uppsala universitet (1); Linköpings universitet (1); Lunds universitet (1); Handelshögskolan i Stockholm (1)

Språk: Engelska (5)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (2)

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