| 1. |
- Dujon, B, et al.
(författare)
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The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
- 1997
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 387:6632, s. 98-102
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Tidskriftsartikel (refereegranskat)abstract
- Chromosome XV was one of the last two chromosomes of Saccharomyces cerevisiae to be discovered(1). It is the third-largest yeast chromosome after chromosomes XII and IV, and is very similar in size to chromosome VII. It alone represents 9% of the yeast genome (8% if ribosomal DNA is included). When systematic sequencing of chromosome XV was started, 93 genes or markers were identified, and most of them were mapped(2). However, very little else was known about chromosome XV which, in contrast to shorter chromosomes, had not been the object of comprehensive genetic or molecular analysis. It was therefore decided to start sequencing chromosome XV only in the third phase of the European Yeast Genome Sequencing Programme, after experience was gained on chromosomes III, XI and II (refs 3-5). The sequence of chromosome XV has been determined from a set of partly overlapping cosmid clones derived from a unique yeast strain, and physically mapped at 3.3-kilobase resolution before sequencing. As well as numerous new open reading frames (ORFs) and genes encoding tRNA or small RNA molecules, the sequence of 1,091,283 base pairs confirms the high proportion of orphan genes and reveals a number of ancestral and successive duplications with other yeast chromosomes.
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| 2. |
- Isleem, Haytham F., et al.
(författare)
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Nonlinear finite element and machine learning modeling of tubed reinforced concrete columns under eccentric axial compression loading
- 2024
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Ingår i: Alexandria Engineering Journal. - : Elsevier. - 1110-0168 .- 2090-2670. ; 92, s. 380-416
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Tidskriftsartikel (refereegranskat)abstract
- There is still insufficient data on the behavior of tubed-reinforced concrete columns (TRCCs) under the eccentric compression. Thus, this research work comprehensively examines the eccentric compression behavior of TRCCs using nonlinear finite element modeling and machine learning (ML). To do this, numerical simulation and parametric analysis based on existing investigations were conducted. In addition to the existing 22 specimens with limited test variables, additional 188 specimens were developed to cover a wide range of parameters, including the load eccentricity, transverse reinforcement spacing, columns’ slenderness ratio, yield strength of steel, and outer steel tube diameter. Additionally, six ML models were created to estimate the ultimate load results. The results indicated that increasing the outer steel tube yield strength and diameter, and reducing the load eccentricity, slenderness ratio, and spacing of the transverse reinforcement enhanced the load-carrying capacity of the columns. The Gaussian process regression model demonstrated superior performance metrics in comparison to other ML models, with the highest R2 values (0.998613 in training and 0.99823 in testing stages) and lowest root mean square error values (0.007213 in training and 0.008471 in testing stages). To save money, time, and resources compared to laboratory testing, an online-based prediction program is finally presented to predict the columns’ ultimate load.
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| 3. |
- Mydin, Md Azree Othuman, et al.
(författare)
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Residual durability, mechanical, and microstructural properties of foamed concrete subjected to various elevated temperatures
- 2024
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Ingår i: Engineering Science and Technology, an International Journal. - : Elsevier. - 2215-0986. ; 55
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Tidskriftsartikel (refereegranskat)abstract
- Three different densities (500 kg/m3, 1000 kg/m3, and 1500 kg/m3) of foamed concrete (FC) were tested alongside mortar with a density of 1980 kg/m3 to investigate how high temperatures affect the qualities of FC. A flow table test was used to examine the fresh qualities of the mixtures. The modulus of elasticity, ultrasonic pulse velocity (UPV), bending strength, split tensile strength, compressive strength, thermal conductivity, porosity, and appearance and colour changes at ambient temperature and after exposure to various high temperatures (100 ◦C, 150 ◦C, 200 ◦C, 400 ◦C, 600 ◦C, and 800 ◦C) were evaluated. To study the effects of varying densities, microstructure analysis was performed utilizing scanning electron microscopy and mercury intrusion porosimetry. According to the findings, the four varied densities appeared dissimilar. FC with lower densities (500 kg/m3 and 1000 kg/m3) showed signs of cracking, while FC with a higher density (1500 kg/m3) enabled for precise detection of the pore connectivity and surface spalling occurrences. High temperatures had less effect on the mortar than FC mixtures. As the temperature increased, the modulus of elasticity, split tensile strength, bending strength, compressive strength, thermal conductivity, and mass loss decreased for all the mortar and FC samples. The UPV values increased marginally up to 100 ◦C before decreasing. This investigation highlighted the need for additional research and code provisions that consider different innovative construction materials and FC constituent classes.
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