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- Kennedy, Beatrice, 1982-, et al.
(författare)
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App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden
- 2022
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- The app-based COVID Symptom Study was launched in Sweden in April 2020 to contribute to real-time COVID-19 surveillance. We enrolled 143,531 study participants (≥18 years) who contributed 10.6 million daily symptom reports between April 29, 2020 and February 10, 2021. Here, we include data from 19,161 self-reported PCR tests to create a symptom-based model to estimate the individual probability of symptomatic COVID-19, with an AUC of 0.78 (95% CI 0.74-0.83) in an external dataset. These individual probabilities are employed to estimate daily regional COVID-19 prevalence, which are in turn used together with current hospital data to predict next week COVID-19 hospital admissions. We show that this hospital prediction model demonstrates a lower median absolute percentage error (MdAPE: 25.9%) across the five most populated regions in Sweden during the first pandemic wave than a model based on case notifications (MdAPE: 30.3%). During the second wave, the error rates are similar. When we apply the same model to an English dataset, not including local COVID-19 test data, we observe MdAPEs of 22.3% and 19.0% during the first and second pandemic waves, respectively, highlighting the transferability of the prediction model.
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- Keramidas, G., et al.
(författare)
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Embedded reconfigurable computing: The ERA approach
- 2013
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Ingår i: IEEE International Conference on Industrial Informatics (INDIN). - 1935-4576. ; , s. 827-832
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Konferensbidrag (refereegranskat)abstract
- The growing complexity and diversity of embedded systems-combined with continuing demands for higher performance and lower power consumption-places increasing pressure on embedded platforms designers. The target of the ERA project is to offer a holistic, multi-dimensional methodology to address these problems in a unified framework exploiting the inter-and intra-synergism between the reconfigurable hardware (core, memory, and network resources), the reconfigurable software (compiler and tools), and the run-time system. Starting from the hardware level, we design our platform via a structured approach that allows integration of reconfigurable computing elements, network fabrics, and memory hierarchy components. These hardware elements can adapt their composition, organization, and even instruction-set architectures to exploit tradeoffs in performance and power. Appropriate hardware resources can be selected both statically at design time and dynamically at run time. Hardware details are exposed to our custom operating system, our custom runtime system, and our adaptive compiler, and are even visible all the way up to the application level. The design philosophy followed in the ERA project proved efficient enough not only to enable a better choice of power/performance trade-offs but also to support fast platform prototyping of high-efficiency embedded system designs. In this paper, we present a brief overview of the design approach, the major outcomes, and the lessons learned in the ERA project.
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