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- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 5. |
- Arvola Orlander, A., et al.
(författare)
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Towards an Understanding of Diffractive Readings of Narratives in the Field of Science Education
- 2018
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Ingår i: Cultural, Social and Political Prespectives in Science Education. - Cham, Switzerland : Springer International Publishing AG. - 1879-7229 .- 1879-7237. - 9783319611907 ; , s. 139-152
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Bokkapitel (refereegranskat)abstract
- In this chapter we seek to challenge the positivistic and traditional way of doing research in the field of science education by turning to posthuman approaches to analyse our data. Feeling trapped in doing research where objects are regarded as having inherent boundaries and fixed properties, we have read data with and through a feminist materialist lens. We are curious to understand how posthuman approaches to explore ways of doing research can be mobilized using Karen Barad’s and Donna Haraway’s theories of diffractive reading. Our aim has been to open up the data to diffract it for new images and thereby to trouble the human centred and objective perspectives of doing research. Instead of taking a distance from our objects of research the diffractive reading has meant that we have infiltrated with our data, a student text and an excerpt from a classroom observation. We have allowed the data to influence us as well as the other way around and thus regarded the research objects as equivalent to ourselves in terms of agency. What came out of this way to tackle our research material is partly a different view of ourselves as scientists and the research objects as having agency, a more intrinsic, emotionally influenced and embodied view. We have got hold of our prejudices and exposed them instead of trying to pretend that they do not exist. Thereby we have taken ethical responsibility in this transparency as well as when seeing the “object” as equally active and meaning making as ourselves. Emotions have been brought to the surface and been used, since we cannot pretend that we are a mind without a body as the Cartesian thought stipulates and which natural science is still leaning on. We think that using the diffractive reading tool from a material feminist perspective has given us insights that would not have been possible to get when taking the anthropocentric and positivistic perspective. It has also proven to be a more honest and thereby more ethical alternative compared to the positivistic version. We have got a better scientific description of the world, a view from somewhere that Haraway asks for (1991).
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| 6. |
- Arvola Orlander, Auli, et al.
(författare)
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Towards an Understanding of Diffractive Readings of Narratives in the Field of Science Education
- 2018
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Ingår i: Cultural, Social, and Political Perspectives in Science Education<em> </em>. - Cham Switzerland : Springer. - 9783319611907 - 9783319611914 ; , s. 139-152
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Bokkapitel (refereegranskat)abstract
- In this chapter we seek to challenge positivist and traditional ways of conducting research in the field of science education by turning to posthuman approaches in order to analyse the data. Feeling trapped when completing research where objects are regarded as having inherent boundaries and fixed properties, we have read data with and through a feminist materialist lens. We are curious to understand how posthuman approaches can be mobilised using Karen Barad’s and Donna Haraway’s theories of diffractive reading. Our aim has been to open up the data to diffract for new images and thereby to trouble the human centred and objective perspectives of carrying out research. Instead of taking a distance from our objects of research, this diffractive reading approach has meant that we have infiltrated the data, a student text and an excerpt from a classroom observation. We have allowed the data to influence us as well as the other way around and thus regarded the research objects as equivalent to ourselves in terms of agency. What resulted from this way of working with the research material is partly a different view of ourselves as scientists and the realisation that research objects can have agency, as well as a more intrinsic, emotionally influenced, ethical and embodied view. The research process in this chapter troubles the human centred perspective, as well as the view of research process as something objective, logical and rational. A perspective that is based on binary thinking and a dichotomous framework.
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| 7. |
- Balaam, Madeline, et al.
(författare)
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Intimate Touch
- 2020
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Ingår i: interactions. - : Association for Computing Machinery. - 1072-5520 .- 1558-3449. ; 27:6, s. 14-17
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 8. |
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| 9. |
- Börjesson, Git, et al.
(författare)
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Att undersöka möjligheter till ämnesdidaktisk progression
- 2019
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Ingår i: Vetenskaplighet i högre utbildning - Erfarenheter från lärarutbildningen. Franck, Olof (red.). - Lund : Studentlitteratur. - 9789144130637 ; , s. 157-178
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- I lärarutbildningen finns sedan lång tid tillbaka ett speciellt intresse för vilka professionella kunskaper en lärare bör ha för att undervisa inom ett ämnesområde, det vill säga vilken ämnesdidaktisk kompetens som krävs för att bedriva undervisning. Det finns i lärarutbildningen också, på samma sätt som i andra utbildningar , ett intresse för progression av lärandet. Progression kan beskrivas som det sätt som lärandet tar sig uttryck, det vill säga ett bevis för resultatet av lärandet hos individer. Det finns forskning när det gäller progression i relation till så väl individens lärande som vad ämnesdidaktisk kunskap och lärande är, och hur det kan tolkas och iscensättas i olika utbildningssammanhang. Trots det så saknas det forskning som kombinerar dessa båda delar, ämnesdidaktiska kunskaper och ämnesdidaktisk progression inom lärarutbildningens kurser. Vi har genom att använda kollegiala samtal försökt synliggöra vad, varför och hur ämnesdidaktik framträder i lärarprogrammets kurser i narurvetenskap och teknik och om, och i så fall hur, ämnesdidaktisk progression kommer till uttryck. Arbetet har inneburit att vi som lärarutbildare och forskare har utvecklat en större förståelse för det ämnesdidaktiska innehållet samt synliggjort möjligheter för kursutveckling relativt en tanke om ämnesdidaktisk progression.
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| 10. |
- Garousi, Javad, et al.
(författare)
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PET imaging of epidermal growth factor receptor expression in tumours using Zr-89-labelled ZEGFR:2377 affibody molecules
- 2016
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Ingår i: International Journal of Oncology. - : Spandidos. - 1019-6439 .- 1791-2423. ; 48:4, s. 1325-1332
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Tidskriftsartikel (refereegranskat)abstract
- Epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor, which is overexpressed in many types of cancer. The use of EGFR-targeting monoclonal antibodies and tyrosine-kinase inhibitors improves significantly survival of patients with colorectal, non-small cell lung cancer and head and neck squamous cell carcinoma. Detection of EGFR overexpression provides important prognostic and predictive information influencing management of the patients. The use of radionuclide molecular imaging would enable non-invasive repeatable determination of EGFR expression in disseminated cancer. Moreover, positron emission tomography (PET) would provide superior sensitivity and quantitation accuracy in EGFR expression imaging. Affibody molecules are a new type of imaging probes, providing high contrast in molecular imaging. In the present study, an EGFR-binding affibody molecule (ZEGFR:2377) was site-specifically conjugated with a deferoxamine (DFO) chelator and labelled under mild conditions (room temperature and neutral pH) with a radionuclide Zr-89. The Zr-89-DFO-ZEGFR:2377 tracer demonstrated specific high affinity (160 +/- 60 pM) binding to EGFR-expressing A431 epidermoid carcinoma cell line. In mice bearing A431 xenografts, Zr-89-DFO-ZEGFR: 2377 demonstrated specific uptake in tumours and EGFR-expressing tissues. The tracer provided tumour uptake of 2.6 +/- 0.5% ID/g and tumour-to-blood ratio of 3.7 +/- 0.6 at 24 h after injection. Zr-89-DFO-ZEGFR: 2377 provides higher tumour-to-organ ratios than anti-EGFR antibody Zr-89-DFO-cetuximab at 48 h after injection. EGFR-expressing tumours were clearly visualized by microPET using Zr-89-DFO-ZEGFR: 2377 at both 3 and 24 h after injection. In conclusion, Zr-89-DFO-ZEGFR: 2377 is a potential probe for PET imaging of EGFR-expression in vivo.
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