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Sökning: WFRF:(Steinhardt L. C.)

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3.
  • Kallander, K., et al. (författare)
  • Universal Versus Conditional Third Day Follow-Up Visit for Children With Nonsevere Unclassified Fever at the Community Level in Ethiopia: Protocol for a Cluster Randomized Noninferiority Trial
  • 2018
  • Ingår i: Jmir Research Protocols. - : JMIR Publications Inc.. - 1929-0748. ; 7:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Under the World Health Organization's integrated community case management strategy, febrile children seen by community health workers (on day 1) without a diagnosable illness and without danger signs are advised to return on day 3, regardless of symptom resolution. This advice might be unnecessary and place additional time and cost burdens on caregivers and community health workers. However, the safety of not following up with respect to children with unclassified fever is unknown. Objective: The objective of this study is to establish the safety of conditional follow-up of nonsevere unclassified fever, that is, nonsevere illness with fever, no malaria, pneumonia, diarrhea, or danger signs, compared with universal follow-up on day 3, through a 2-arm cluster randomized controlled noninferiority trial. Methods: The study is being conducted in 3 districts in southwest Ethiopia. A total of 25 health facilities are randomized to one of the 2 intervention arms; all 144 health posts and 284 community health workers are included. All enrolled children are followed-up after 1 week (on day 8) for re-assessment. If still sick on day 8, additional follow-up takes place after 2 weeks (day 15) and 1 month (day 29). To demonstrate that there is no significant increase in the percentage of children deteriorating clinically, the sample size needed for a noninferiority margin of 4%, a power of 80%, an alpha of 5%, and a design effect of 3 is 4284 children with unclassified fever. Main outcome is treatment failure on day 8, defined as death, hospitalization, one or more danger signs, or persistent fever. Results: The project was funded in 2015 and enrollment was completed 2016. Data analysis is currently under way, and the first results are expected to be submitted for publication in 2018. Conclusions: This study addresses the question as to whether there is any benefit in recommending universal follow-up among children seen for nonsevere unclassified fever, or whether parents can be counseled to return in the event of persistent fever, using a cluster randomized controlled trial design embedded in a national program. Outcomes will be relevant for policy makers and are important for the evaluation of current and future World Health Organization guidelines for the management of children with fever.
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4.
  • Karlgren, Daniel, et al. (författare)
  • High-angular-momentum structures in Zn-64
  • 2004
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 69, s. 1-034330
  • Tidskriftsartikel (refereegranskat)abstract
    • High-angular-momentum states in Zn-64 were populated in the Ca-40(Si-28,4p) reaction at a beam energy of 122 MeV. Evaporated, light, charged particles were identified by the Microball, while gamma rays were detected using the Gammasphere array. The main focus of this paper is on two strongly coupled, collective bands. The yrast band, which was previously known, has been linked to lower-lying states establishing the excitation energies and angular momenta of in-band states for the first time. The newly identified excited band decays to the yrast band but firm angular-momentum assignments could not be made. In order to interpret these structures cranked-Nilsson-Strutinsky calculations have been performed. The calculations have been extended to account for the distribution of nucleons within a configuration. The yrast collective band is interpreted as based on the pi(f(7/2))(-1)(p(3/2)f(5/2))(2)(g(9/2))(1)nu(p(3/2)f(5/2))(4)(g(9/2))(2) configuration. There are several possible interpretations of the second band but it is difficult to distinguish between the different possibilities.
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5.
  • Sun, Fengwu, et al. (författare)
  • Extensive Lensing Survey of Optical and Near-infrared Dark Objects (El Sonido): HST H-faint Galaxies behind 101 Lensing Clusters
  • 2021
  • Ingår i: Astrophysical Journal. - : American Astronomical Society. - 1538-4357 .- 0004-637X. ; 922:2
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a Spitzer/IRAC survey of H-faint (H-160 greater than or similar to 26.4, < 5 sigma) sources in 101 lensing cluster fields. Across a CANDELS/Wide-like survey area of similar to 648 arcmin(2) (effectively similar to 221 arcmin(2) in the source plane), we have securely discovered 53 sources in the IRAC Channel-2 band (CH2, 4.5 mu m; median CH2 = 22.46 +/- 0.11 AB mag) that lack robust HST/WFC3-IR F160W counterparts. The most remarkable source in our sample, namely ES-009 in the field of Abell 2813, is the brightest H-faint galaxy at 4.5 mu m known so far (CH2 = 20.48 +/- 0.03 AB mag). We show that the H-faint sources in our sample are massive (median M-star = 10 10.3 +/- 0.3 M-circle dot, star-forming (median star formation rate =1001 M-circle dot yr(-1)), and dust-obscured (A(v) = 2.6 +/- 0.3) galaxies around a median photometric redshift of z = 3.9 +/- 0.4. The stellar continua of 14 H-faint galaxies can be resolved in the CH2 band, suggesting a median circularized effective radius (R-e,R-circ; lensing corrected) of 1.9 +/- 0.2 kpc and <1.5 kpc for the resolved and whole samples, respectively. This is consistent with the sizes of massive unobscured galaxies at z similar to 4, indicating that H-faint galaxies represent the dusty tail of the distribution of a wider galaxy population. Comparing with the ALMA dust continuum sizes of similar galaxies reported previously, we conclude that the heavy dust obscuration in H-faint galaxies is related to the compactness of both stellar and dust continua (R-e,R-circ similar to 1 kpc). These H-faint galaxies make up 161 3 % of the galaxies in the stellar-mass range of 10(10) - 10(11.2) M-circle dot at z = 3 similar to 5, contributing to 8(-4)(+8)% of the cosmic star formation rate density in this epoch and likely tracing the early phase of massive galaxy formation.
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6.
  • Gadea, A., et al. (författare)
  • Spectroscopy at N=Z with EUROBALL III
  • 1999
  • Ingår i: AIP Conference Proceedings. - : AIP. - 1551-7616 .- 0094-243X. ; 495, s. 195-198
  • Konferensbidrag (refereegranskat)abstract
    • A complete study of the nuclear structure by means of gamma spectroscopy requires, in addition to the high resolution gamma measurement and accurate DCO's or angular distributions, the information concerning the Electric or Magnetic character of the transition. This information for transitions in nuclei far from stability valley is now reachable in the new generation of Ge-arrays based in composite detectors. EUROBALL III is a good example with the high polarization sensitivity of the 90 degrees ring of Clovers. The Polarization correlations PCO's measured in coincidence with the Cluster detectors permits to investigate transitions in weakly populated nuclei. In this contribution we present results on medium mass N=Z nuclei measured with EUROBALL III coupled with light particle ancillary detectors.
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7.
  • Källander, K., et al. (författare)
  • Universal versus conditional day 3 follow-up for children with non-severe unclassified fever at the community level in Ethiopia: A cluster-randomised non-inferiority trial
  • 2018
  • Ingår i: PLoS Medicine. - : Public Library of Science (PLoS). - 1549-1277 .- 1549-1676. ; 15:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: With declining malaria prevalence and improved use of malaria diagnostic tests, an increasing proportion of children seen by community health workers (CHWs) have unclassified fever. Current community management guidelines by WHO advise that children seen with non-severe unclassified fever (on day 1) should return to CHWs on day 3 for reassessment. We compared the safety of conditional follow-up reassessment only in cases where symptoms do not resolve with universal follow-up on day 3. Methods and findings: We undertook a 2-arm cluster-randomised controlled non-inferiority trial among children aged 2–59 months presenting with fever and without malaria, pneumonia, diarrhoea, or danger signs to 284 CHWs affiliated with 25 health centres (clusters) in Southern Nations, Nationalities, and Peoples’ Region, Ethiopia. The primary outcome was treatment failure (persistent fever, development of danger signs, hospital admission, death, malaria, pneumonia, or diarrhoea) at 1 week (day 8) of follow-up. Non-inferiority was defined as a 4% or smaller difference in the proportion of treatment failures with conditional follow-up compared to universal follow-up. Secondary outcomes included the percentage of children brought for reassessment, antimicrobial prescription, and severe adverse events (hospitalisations and deaths) after 4 weeks (day 29). From December 1, 2015, to November 30, 2016, we enrolled 4,595 children, of whom 3,946 (1,953 universal follow-up arm; 1,993 conditional follow-up arm) adhered to the CHW’s follow-up advice and also completed a day 8 study visit within ±1 days. Overall, 2.7% had treatment failure on day 8: 0.8% (16/1,993) in the conditional follow-up arm and 4.6% (90/1,953) in the universal follow-up arm (risk difference of treatment failure −3.81%, 95% CI −∞, 0.65%), meeting the prespecified criterion for non-inferiority. There were no deaths recorded by day 29. In the universal follow-up arm, 94.6% of caregivers reported returning for reassessment on day 3, in contrast to 7.5% in the conditional follow-up arm (risk ratio 22.0, 95% CI 17.9, 27.2, p < 0.001). Few children sought care from another provider after their initial visit to the CHW: 3.0% (59/1,993) in the conditional follow-up arm and 1.1% (22/1,953) in the universal follow-up arm, on average 3.2 and 3.4 days later, respectively, with no significant difference between arms (risk difference 1.79%, 95% CI −1.23%, 4.82%, p = 0.244). The mean travel time to another provider was 2.2 hours (95% CI 0.01, 5.3) in the conditional follow-up arm and 2.6 hours (95% CI 0.02, 4.5) in the universal follow-up arm (p = 0.82); the mean cost for seeking care after visiting the CHW was 26.5 birr (95% CI 7.8, 45.2) and 22.8 birr (95% CI 15.6, 30.0), respectively (p = 0.69). Though this study was an important step to evaluate the safety of conditional follow-up, the high adherence seen may have resulted from knowledge of the 1-week follow-up visit and may therefore not transfer to routine practice; hence, in an implementation setting it is crucial that CHWs are well trained in counselling skills to advise caregivers on when to come back for follow-up. Conclusions: Conditional follow-up of children with non-severe unclassified fever in a low malaria endemic setting in Ethiopia was non-inferior to universal follow-up through day 8. Allowing CHWs to advise caregivers to bring children back only in case of continued symptoms might be a more efficient use of resources in similar settings. © 2018 Public Library of Science. All Rights Reserved.
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8.
  • Plettner, C., et al. (författare)
  • Very high rotational frequencies and band termination in 73Br
  • 2000
  • Ingår i: Physical Review C - Nuclear Physics. - 0556-2813. ; 62:1, s. 143131-143136
  • Tidskriftsartikel (refereegranskat)abstract
    • Rotational bands in 73Br have been investigated up to spins of I = 65/2 using the EUROBALL III spectrometer. One of the negative-parity bands displays the highest rotational frequency ℏω= 1.85 MeV reported to date in nuclei with A ≥ 25. At high frequencies, the experimental J(2) dynamic moment of inertia for all bands decreases to very low values, J(2) ≤ 10ℏ2 MeV-1. The bands are described in the configuration-dependent cranked Nilsson-Strutinsky model. The calculations indicate that one of the negative-parity bands is observed up to its terminating single-particle state at spin 63/2. This result establishes the first band termination in the A ≈ 70 mass region.
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9.
  • Rainovski, G, et al. (författare)
  • Shape coexistence at high spin in the N = Z+2 nucleus Se-70
  • 2002
  • Ingår i: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899. ; 28:10, s. 2617-2625
  • Tidskriftsartikel (refereegranskat)abstract
    • The nucleus Se-70 was studied using the Ca-40(Ca-40, 2alpha2p) reaction at a beam energy of 185 MeV. Gamma rays were measured with the EUROBALL III spectrometer. The known positive-parity bands have been extended and one new band of positive parity and two of negative parity have been identified. These bands are interpreted in terms of the cranked Nilsson-Strutinsky approach. Calculations suggest that the two negative-parity bands, which have the same signature, are both based on a configuration with two protons and three neutrons lifted from the fp shell to the g(9/2) orbital, but at different nuclear shapes. This represents a shape coexistence at high spin.
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