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- Jarnheimer, Per-åke, et al.
(författare)
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Fluoroquinolone Antibiotics in a Hospital Sewage Line; Occurrence, Distribution and Impact on Bacterial Resistance
- 2004
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 36:10, s. 752-5
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Tidskriftsartikel (refereegranskat)abstract
- In hospital sewage lines, human faecal bacteria are exposed to antibiotics, posing a risk for selection of antibiotic resistant microorganisms. We constructed a system for continuous sampling in a hospital sewage line that allowed us to study longitudinal establishment of bacteria, concentrations of antibiotics, and selection of bacterial resistance in waste water, sediment and biofilm. The focus in this study was on fluoroquinolones, a widely used group of antibiotics with increasing resistance problems. We found low levels of ciprofloxacin and ofloxacin in waste water but high concentrations in sediment. Despite the high levels of fluoroquinolones bound to sediment, we did not find any development of resistance against fluoroquinolones in Enterobacteriacae spp. and faecal enterococci isolated from sediment.
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| 3. |
- Johannessen, Åse, et al.
(författare)
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Strategies for building resilience to hazards in water, sanitation and hygiene (WASH) systems : the role of public private partnerships
- 2014
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Ingår i: International Journal of Disaster Risk Reduction. - : Elsevier BV. - 2212-4209. ; 10:part A, s. 102-115
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this paper is to enhance understanding of how the resilience of water, sanitation and hygiene (WASH) systems to hazards can be improved. In turn, this aims to inform different strategies for public and private partnerships (PPPs). In a new approach, to acknowledge the multi levelled nature of resilience; risk at the relevant levels are taken into account, (regional/river basin, urban area, and individual). For these levels, we first describe the different components of risk, vulnerability and resilience of the WASH system that influence people׳s exposure to hazards. We illustrate these components using examples from case studies in the literature. Using a social learning lens - a crucial ingredient of resilience - we examine opportunities for reducing risks through improving public–private engagement. These are presented as strategies which could guide investment decisions: As pressures from climate change and development add up, businesses must become aware of the risks involved in operating and investing without considering ecosystem health, both in terms of the services they provide for mitigating floods and droughts, as well as in terms of the development approaches that define how ecosystems are managed (e.g. “making space” for, rather than controlling water). There is a need to develop an institutional culture that strives towards greener and more resilient urban environments with the help of various quality assurance methods. Partnerships must reach the poorer customer base, encourage informal small entrepreneurs, and boost financial mechanisms (e.g. micro-insurance, micro-finance) to support the most vulnerable in society
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- Johannessen, Åse, et al.
(författare)
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Transforming urban water governance through social (triple-loop) learning
- 2019
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Ingår i: Environmental Policy and Governance. - : Wiley. - 1756-932X .- 1756-9338. ; 29:2, s. 144-154
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Tidskriftsartikel (refereegranskat)abstract
- The sustainable development of cities is threatened by a worldwide water crisis. Improved social learning is urgently needed to transform urban water governance and make it more integrated and adaptive. However, empirical studies remain few and fragmented. Therefore, the aim of this paper is to analyse how social learning has supported or inhibited sustainable transformations in urban water governance. On the basis of multiple case studies conducted in urban, flood-prone areas in Colombia, the Philippines, South Africa, India, and Sweden, we study learning processes related to different aspects of water management and governance. Our results show that transformations in water governance are often triggered by crises, whereas other potentials for transformation are not tapped into. Furthermore, learning is often inhibited by “lock-ins” created by powerful actors. We conclude that there is a need for more proactive design of governance structures for triple-loop learning that take into account the identified barriers and supporting principles.
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| 6. |
- Ngubane, Zesizwe, et al.
(författare)
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Multi-criteria decision analysis framework for engaging stakeholders in river pollution risk management
- 2024
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- Water pollution presents a substantial environmental challenge with extensive implications for water resources, ecosystem sustainability, and human health. Using a South African catchment, this study aimed to provide watershed managers with a framework for selecting best management practices (BMPs) to reduce pollution and the related risk to river users, while also including the perspectives of key catchment stakeholders. The framework encompassed the identification of and consultation with key stakeholders within the catchment. A Multi-Criteria Decision Analysis (MCDA) methodology using the Simple Multi-Attribute Rating Technique for Enhanced Stakeholder Take-up (SMARTEST) was used to identify and prioritise suitable BMPs in a case study. Decision alternatives and assessment criteria as well as their weights were derived based on stakeholder responses to a two-stage survey. Stakeholders included those utilising the river for domestic and recreational purposes, municipal representatives, scientists, NGOs, and engineers. The assessment of decision alternatives considered environmental, economic, and social criteria. The aggregated scores for decision alternatives highlighted the significance of involving stakeholders throughout the decision process. This study recommends the pairing of structural and non-structural BMPs. The findings provide valuable insights for catchment managers, policymakers, and environmental stakeholders seeking inclusive and effective pollution mitigation strategies in a catchment.
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| 7. |
- Ngubane, Zesizwe, et al.
(författare)
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Quantitative assessment of human health risks from chemical pollution in the uMsunduzi River, South Africa
- 2023
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Ingår i: Environmental Science and Pollution Research. - : Springer. - 0944-1344 .- 1614-7499. ; 30:55, s. 118013-118024
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Tidskriftsartikel (refereegranskat)abstract
- A quantitative chemical risk assessment was performed using published data as well as data from the official monitoring programme for the uMsunduzi River in KwaZulu-Natal, South Africa. The chemicals assessed were organochlorinated pesticides (OCPs), pharmaceuticals and personal care products (PPCPs), heavy metals, and nitrates and phosphates. The water from uMsunduzi River is used locally without treatment. Consequently, the exposure routes investigated were via ingestion during domestic drinking and incidental ingestion during recreational activities, which were swimming and non-competitive canoeing, for both adults and children. For the individual chemicals, non-carcinogenic risks using the hazard quotient (HQ) and carcinogenic risks using the cancer risk (CR) were quantified. It was found that the exposed population is likely to experience non-carcinogenic effects from pesticides and phosphates, but not from PPCPs, heavy metals and nitrates. This study also found that the carcinogenic risks for OCPs were higher than the tolerable limit of 10-5, while for lead the risk was below the tolerable limit. Some of the activities that potentially contribute to chemicals onto the uMsunduzi River are subsistence farming, small plantations, illegal dumping, industries, and broken sewers. The findings of this study may act as the technical foundation for the introduction of pollution reduction measures within the catchment, including public education.
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| 8. |
- Ottoson, Jakob, et al.
(författare)
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A longitudinal study of antimicrobial resistant faecal bacteria in sediments collected from a hospital wastewater system
- 2012
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Ingår i: Infection Ecology & Epidemiology. - : Informa UK Limited. - 2000-8686. ; 2, s. 7438-
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Tidskriftsartikel (refereegranskat)abstract
- Objective:The objective with this study was to determine and follow antimicrobial resistance in faecal bacteria over time in hospital wastewater pipe sediment. A further aim was to determine bacterial growth rates of sensitive, intermediate and resistant intestinal enterococci in different ciprofloxacin concentrations as a measure of bacterial fitness.Methods:A system enabling the collection of settled particles over time was installed at Kalmar County Hospital. Samples were collected bi-monthly for a 14-month period. Coliform bacteria and enterococci were isolated from the sediment with standard methods and investigated for resistance to ciprofloxacin (CIP), imipenem (IMI), trimetroprim-sulfamethoxazole (TS), ampicillin (AMP) and vancomycin (VAN) by the disc diffusion method. Resistant isolates were further typed with the PhenePlateTM system. Growth assessments were performed with an automated spectrophotometer.Results:The rate of intestinal enterococci resistance was < 0.6, 1.3, 1.9 and 13% to VAN, IMI, AMP and CIP respectively. Coliform resistance frequencies were 1.1, 2.2 and 2.2% to CIP, IMI and TS respectively. At two sampling occasions, significantly higher rates of ciprofloxacin resistant enterococci were found and the establishment of a resistant clone in the sewer was indicated by the PhP-analysis. Ciprofloxacin resistant intestinal enterococci had a significantly longer lag-phase time than sensitive isolates, but from 500 µg ml-1 (half MIC) resistant isolates had a competitive advantage in terms of significantly faster generation time.Discussion:Despite high concentration of antimicrobials in the sediment, resistance frequencies were generally low. This can depend on limited growth possibilities for faecal bacteria. However, the establishment of a resistant clone shows that hospital sewers can serve as a reservoir for antibiotic resistant bacteria.
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| 9. |
- Ottoson, Jakob, et al.
(författare)
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Faecal contamination of greywater and associated microbial risks
- 2003
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Ingår i: Water Research. - 0043-1354 .- 1879-2448. ; 37:3, s. 645-655
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Tidskriftsartikel (refereegranskat)abstract
- The faecal contamination of greywater in a local treatment system at Vibyasen, north of Stockholm, Sweden was quantified using faecal indicator bacteria and chemical biomarkers. Bacterial indicator densities overestimated the faecal load by 100-1000-fold when compared to chemical biomarkers. Based on measured levels of coprostanol, the faecal load was estimated to be 0.04 g person(-1) day(-1). Prevalence of pathogens in the population and the faccal load were used to form the basis of a screening-level quantitative microbial risk assessment (QMRA) that was undertaken for rotavirus, Salmonella typhimurium, Campylobacter jejuni, Giardia lamblia and Cryptosporidium parvum. The different exposure scenarios simulated-direct contact, irrigation of sport fields and groundwater recharge-gave unacceptably high rotavirus risks (0.04
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