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1.	Thagaard, J, et al. (author) Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer 2023 In: The Journal of pathology. - 1096-9896. ; 260:5, s. 498-513 Journal article (peer-reviewed)
2.	Jahangir, CA, et al. (author) Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer 2024 In: JOURNAL OF PATHOLOGY. - 0022-3417 .- 1096-9896. ; 262:3, s. 271-288 Research review (other academic/artistic)
3.	Page, DB, et al. (author) Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer 2023 In: The Journal of pathology. - 1096-9896. ; 260:5, s. 514-532 Journal article (peer-reviewed)
4.	Hofman, P, et al. (author) Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future 2021 In: ESMO open. - : Elsevier BV. - 2059-7029. ; 6:1, s. 100024- Journal article (peer-reviewed)
5.	Goeppert, B, et al. (author) Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities 2020 In: Hepatology (Baltimore, Md.). - : Ovid Technologies (Wolters Kluwer Health). - 1527-3350 .- 0270-9139. ; 72:4, s. 1253-1266 Journal article (peer-reviewed)
6.	Christopoulos, P, et al. (author) TOGETHER: Pooled real-world datasets of METex14 skipping NSCLC and adjusted comparison of upfront (chemo-) immunotherapy with tepotinib from VISION 2023 In: ANNALS OF ONCOLOGY. - 0923-7534. ; 34 Conference paper (other academic/artistic)
7.	Edsjö, A., et al. (author) High-throughput molecular assays for inclusion in personalised oncology trials – State-of-the-art and beyond 2024 In: Journal of Internal Medicine. - 0954-6820. ; 295:6, s. 785-803 Journal article (peer-reviewed)abstract In the last decades, the development of high-throughput molecular assays has revolutionised cancer diagnostics, paving the way for the concept of personalised cancer medicine. This progress has been driven by the introduction of such technologies through biomarker-driven oncology trials. In this review, strengths and limitations of various state-of-the-art sequencing technologies, including gene panel sequencing (DNA and RNA), whole-exome/whole-genome sequencing and whole-transcriptome sequencing, are explored, focusing on their ability to identify clinically relevant biomarkers with diagnostic, prognostic and/or predictive impact. This includes the need to assess complex biomarkers, for example microsatellite instability, tumour mutation burden and homologous recombination deficiency, to identify patients suitable for specific therapies, including immunotherapy. Furthermore, the crucial role of biomarker analysis and multidisciplinary molecular tumour boards in selecting patients for trial inclusion is discussed in relation to various trial concepts, including drug repurposing. Recognising that today's exploratory techniques will evolve into tomorrow's routine diagnostics and clinical study inclusion assays, the importance of emerging technologies for multimodal diagnostics, such as proteomics and in vivo drug sensitivity testing, is also discussed. In addition, key regulatory aspects and the importance of patient engagement in all phases of a clinical trial are described. Finally, we propose a set of recommendations for consideration when planning a new precision cancer medicine trial. © 2024 The Authors. Journal of Internal Medicine published by John Wiley & Sons Ltd on behalf of Association for Publication of The Journal of Internal Medicine.
8.	Horak, P, et al. (author) Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC) 2022 In: Genetics in medicine : official journal of the American College of Medical Genetics. - : Elsevier BV. - 1530-0366. ; 24:5, s. 986-998 Journal article (peer-reviewed)
9.	Christopoulos, P, et al. (author) Real-world data for precision cancer medicine-A European perspective 2023 In: Genes, chromosomes & cancer. - 1098-2264. Journal article (peer-reviewed)
10.	Christopoulos, P, et al. (author) Real-world data for precision cancer medicine-A European perspective 2023 In: Genes, chromosomes & cancer. - : Wiley. - 1098-2264 .- 1045-2257. ; 62:9, s. 557-563 Journal article (peer-reviewed)

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Result 1-10 of 12

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Type of publication: journal article (9); research review (2); conference paper (1)

Type of content: peer-reviewed (10); other academic/artistic (2)

Author/Editor: Penault-Llorca, F (4); Tanaka, S. (3); Mehrotra, R (3); Walter, T. (3); Acs, B (3); Hartman, J (3); show more...; Fineberg, S (3); Kos, Z (3); Laenkholm, AV (3); Rau, TT (3); Salgado, R (3); Viale, G (3); Adams, S. (3); Ly, A (3); Thomas, M (3); Rahman, A. (3); Grigoriadis, A (3); Sayed, S (3); Pruneri, G (3); Larsimont, D (3); Michiels, S (3); Stovgaard, ES (3); Thagaard, J (3); Denkert, C (3); AbdulJabbar, K (3); Savas, P (3); Madabhushi, A (3); Horlings, HM (3); Ciompi, F (3); Moore, DA (3); Lennerz, JK (3); Kirtani, P (3); Demaria, S (3); Sotiriou, C (3); Gonzalez-Ericsson, P (3); Loibl, S (3); Hanna, MG (3); Saltz, J (3); Kovacs, A (3); Gnjatic, S (3); Vieth, M (3); Li, XX (3); Mushtaq, S (3); Mittal, S (3); Rapoport, BL (3); Van der Laak, J (3); Badve, S (3); Sur, D. (3); Thompson, EA (3); Christopoulos, P (3); show less...

University: Karolinska Institutet (11); Lund University (2); Uppsala University (1)

Language: English (12)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

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