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- Solé-Padullés, Cristina, et al.
(författare)
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No Association Between Loneliness, Episodic Memory and Hippocampal Volume Change in Young and Healthy Older Adults : A Longitudinal European Multicenter Study
- 2022
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Ingår i: Frontiers in Aging Neuroscience. - : Frontiers Media S.A.. - 1663-4365 .- 1663-4365. ; 14
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Tidskriftsartikel (refereegranskat)abstract
- Background: Loneliness is most prevalent during adolescence and late life and has been associated with mental health disorders as well as with cognitive decline during aging. Associations between longitudinal measures of loneliness and verbal episodic memory and brain structure should thus be investigated.Methods: We sought to determine associations between loneliness and verbal episodic memory as well as loneliness and hippocampal volume trajectories across three longitudinal cohorts within the Lifebrain Consortium, including children, adolescents (N = 69, age range 10–15 at baseline examination) and older adults (N = 1468 over 60). We also explored putative loneliness correlates of cortical thinning across the entire cortical mantle.Results: Loneliness was associated with worsening of verbal episodic memory in one cohort of older adults. Specifically, reporting medium to high levels of loneliness over time was related to significantly increased memory loss at follow-up examinations. The significance of the loneliness-memory change association was lost when eight participants were excluded after having developed dementia in any of the subsequent follow-up assessments. No significant structural brain correlates of loneliness were found, neither hippocampal volume change nor cortical thinning.Conclusion: In the present longitudinal European multicenter study, the association between loneliness and episodic memory was mainly driven by individuals exhibiting progressive cognitive decline, which reinforces previous findings associating loneliness with cognitive impairment and dementia.
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- Stiernstedt, Johanna, 1974, et al.
(författare)
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Environmental and Quality Analysis of Aqueous Tape Casting
- 2011
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Ceramic tapes are traditionally produced by tape casting using organic solvents. The use of organic solvents has been questioned due to health, environmental and fire hazard risks. The use of water-based tape casting can reduce these problems. This study contains an environmental assessment of ceramic tapes in a life cycle perspective. Two tape casting techniques, using different solvents during the tape casting, are analyzed from cradle to grave, ie, from raw material production, manufacturing, application and recycling. The functional unit was defined as tape with 1000 gram of alumina content. Tape casting with water based solvent was compared to tape casting with hydrocarbon based solvent. In principal, only differing processes were examined. There are also quality issues associated with water based tape casting: the drying is slower and can cause cracking, air bubbles can be entrapped, and in some cases there can be problems with wetting. These problems can be handled by controlling the colloidal and rheological properties and using a system with high solids loading. In conclusion the results show that water based tape casting gives tapes of high quality and that a lower environmental impact is possible compared to solvent based tape casting. It is further shown that the sintering of the green tape, which follows the tape casting, is probably the process with most climate impact in the life cycle of a ceramic tape.
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