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Numrering	Referens	Omslagsbild	Hitta
1.	Bonjer, HJ, et al. (författare) Impact of hospital case volume on short-term outcome after laparoscopic operation for colonic cancer 2005 Ingår i: Surgical endoscopy. - : Springer Science and Business Media LLC. - 1432-2218 .- 0930-2794. ; 19:5, s. 687-692 Tidskriftsartikel (refereegranskat)
2.	Aziz, N. A., et al. (författare) Weight loss in Huntington disease increases with higher CAG repeat number 2008 Ingår i: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 71:19, s. 1506-1513 Tidskriftsartikel (refereegranskat)abstract Objective: Huntington disease (HD) is a hereditary neurodegenerative disorder caused by an expanded number of CAG repeats in the huntingtin gene. A hallmark of HD is unintended weight loss, the cause of which is unknown. In order to elucidate the underlying mechanisms of weight loss in HD, we studied its relation to other disease characteristics including motor, cognitive, and behavioral disturbances and CAG repeat number. Methods: In 517 patients with early stage HD, we applied mixed-effects model analyses to correlate weight changes over 3 years to CAG repeat number and various components of the Unified Huntington's Disease Rating Scale (UHDRS). We also assessed the relation between CAG repeat number and body weight and caloric intake in the R6/2 mouse model of HD. Results: In patients with HD, mean body mass index decreased with -0.15 units per year (p < 0.001). However, no single UHDRS component, including motor, cognitive, and behavioral scores, was independently associated with the rate of weight loss. Patients with HD with a higher CAG repeat number had a faster rate of weight loss. Similarly, R6/2 mice with a larger CAG repeat length had a lower body weight, whereas caloric intake increased with larger CAG repeat length. Conclusions: Weight loss in Huntington disease (HD) is directly linked to CAG repeat length and is likely to result from a hypermetabolic state. Other signs and symptoms of HD are unlikely to contribute to weight loss in early disease stages. Elucidation of the responsible mechanisms could lead to effective energy-based therapeutics. Neurology (R) 2008;71:1506-1513
3.	Aziz, N. A., et al. (författare) Weight loss in Huntington's disease is related to the number of CAG repeats 2008 Ingår i: Journal of Neurology, Neurosurgery and Psychiatry. - 0022-3050. ; 79:Supplement 1, s. 17-17 Konferensbidrag (refereegranskat)
4.	Gratwohl, A, et al. (författare) Economics and Outcome After Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study 2015 Ingår i: EBioMedicine. - : Elsevier BV. - 2352-3964. ; 2:12, s. 2101-2109 Tidskriftsartikel (refereegranskat)
5.	Nacak, H, et al. (författare) Uric acid is not associated with decline in renal function or time to renal replacement therapy initiation in a referred cohort of patients with Stage III, IV and V chronic kidney disease 2015 Ingår i: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 1460-2385. ; 30:12, s. 2039-2045 Tidskriftsartikel (refereegranskat)

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Resultat 1-5 av 5

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Typ av publikation: tidskriftsartikel (4); konferensbidrag (1)

Typ av innehåll: refereegranskat (5)

Författare/redaktör: Stijnen, T. (5); Brundin, Patrik (2); Aziz, N. A. (2); van der Burg, Jorien ... (2); Landwehrmeyer, G. B. (2); Roos, R. A. C. (2); visa fler...; Lundberg, O. (1); Wittich, P. (1); Giraudo, G. (1); Evans, M. (1); Carrero, JJ (1); Desvignes, G. (1); Lindgren, PG (1); Snowden, JA (1); Janson, M (1); Påhlman, Lars (1); Ljungman, P (1); Dekker, FW (1); Niederwieser, D (1); Qureshi, AR (1); Heikkinen, T (1); Lindholm, E. (1); Raab, Y (1); van Diepen, M (1); Akerlund, JE (1); Kroger, N (1); Mohty, M (1); Anderberg, B (1); Dreger, P (1); Smedh, K. (1); Haglind, E (1); Schwandner, O (1); Gratwohl, A (1); Nagler, A (1); Cuesta, MA (1); Rambaldi, A (1); Skullman, S. (1); Nacak, H (1); Kuhry, E. (1); Kressner, U (1); Apperley, J (1); Sureda, A (1); Nystrom, PO (1); Dahlberg, M. (1); Bonjer, HJ (1); Jeekel, J (1); Kazemier, G (1); Monson, JRT (1); Quircke, P (1); Trede, M (1); visa färre...

Lärosäte: Karolinska Institutet (3); Lunds universitet (2); Uppsala universitet (1)

Språk: Engelska (5)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (2)

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