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Sökning: WFRF:(Ström Folke)

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1.
  • Bergeron, Tor, et al. (författare)
  • 'Fimbulvinter'
  • 1956
  • Ingår i: Fornvännen. - 0015-7813 .- 1404-9430. ; 51, s. 1-18
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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2.
  • Hillerdal, Gunnar, et al. (författare)
  • Comparison of lung volume reduction surgery and physical training on health status and physiologic outcomes : a randomized controlled clinical trial
  • 2005
  • Ingår i: Chest. - : Elsevier BV. - 0012-3692 .- 1931-3543. ; 128:5, s. 3489-3499
  • Tidskriftsartikel (refereegranskat)abstract
    • STUDY OBJECTIVES: In 1996, researchers in Sweden initiated a collaborative randomized study comparing lung volume reduction surgery (LVRS) and physical training with physical training alone. The primary end point was health status; secondary end points included survival and physiologic measurements.DESIGN: After an initial 6-week physical training program, researchers' patients were randomized to either LVRS (surgical group [SG]) with continued training for 3 months, or to continued training alone (training group [TG]) for 1 year.SETTING: All seven thoracic surgery centers in Sweden.PATIENTS: All patients in Sweden with severe emphysema fulfilling inclusion criteria for LVRS.INTERVENTIONS: Patients randomized to surgery underwent a median sternotomy, except for a few patients in whom thoracotomy or video-assisted thoracoscopy were performed. In the TG, supervised physical training continued for 1 year; in the SG, supervised physical training continued for 3 months postoperatively.MEASUREMENTS AND RESULTS: Fifty-three patients were included in each group. Six in-hospital deaths occurred after surgery (12%), and one more death occurred during follow-up. Two deaths occurred in the TG. The difference in death rates between the groups was not statistically significant. Health status, as measured by St. George Respiratory Questionnaire (SGRQ) [total scale score mean difference at 1 year, 14.7; 95% confidence interval (CI), 9.8 to 19.7] as well as by the Medical Outcomes Study Short-Form General Health Survey (physical function scale score mean difference at 1 year, 19.7; 95% CI, 12.1 to 27.3) was improved from baseline in the SG compared with the TG. FEV(1), residual volume, and shuttle walking test values also improved in the SG but not in the TG after 6 months and 12 months.CONCLUSIONS: In severe emphysema, LVRS can improve health status in survivors but is associated with mortality risk. The effects are stable for at least 1 year. Physical training alone failed to achieve a similar improvement.
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