| 1. |
- Oenning, AC, et al.
(författare)
-
Halve the dose while maintaining image quality in paediatric Cone Beam CT
- 2019
-
Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1, s. 5521-
-
Tidskriftsartikel (refereegranskat)abstract
- Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both “ultra-low dose” protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT.
|
|
| 2. |
|
|
| 3. |
- Belmans, N, et al.
(författare)
-
Quantification of DNA Double Strand Breaks and Oxidation Response in Children and Adults Undergoing Dental CBCT Scan
- 2020
-
Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1, s. 2113-
-
Tidskriftsartikel (refereegranskat)abstract
- Assessing the possible biological effects of exposure to low doses of ionizing radiation (IR) is one of the prime challenges in radiation protection, especially in medical imaging. Today, radiobiological data on cone beam CT (CBCT) related biological effects are scarce. In children and adults, the induction of DNA double strand breaks (DSBs) in buccal mucosa cells and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) and antioxidant capacity in saliva samples after CBCT examination were examined. No DNA DSBs induction was observed in children nor adults. In children only, an increase in 8-oxo-dG levels was observed 30 minutes after CBCT. At the same time an increase in antioxidant capacity was observed in children, whereas a decrease was observed in adults. Our data indicate that children and adults react differently to IR doses associated with CBCT. Fully understanding these differences could lead to an optimal use of CBCT in different age categories as well as improved radiation protection guidelines.
|
|
| 4. |
- Proletov, Ian, et al.
(författare)
-
Primary and secondary glomerulonephritides 1.
- 2014
-
Ingår i: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 1460-2385. ; 29 Suppl 3:May, s. 186-200
-
Tidskriftsartikel (refereegranskat)
|
|
| 5. |
|
|
| 6. |
- Gohardani, Navid, et al.
(författare)
-
Stakeholders and the Decision Making Process Concerning Sustainable Renovation and Refurbishment in Sweden, Denmark and Cyprus
- 2013
-
Ingår i: Architecture & Environment. - : Sciknow Publications Ltd.. - 2329-2288. ; 1:2, s. 21-28
-
Tidskriftsartikel (refereegranskat)abstract
- This article examines the decision making process related to sustainable renovation and refurbishment in buildings. The utilized methodology identifies three distinct phases in order to instigate an engagement in sustainable renovation, by means of questionnaires and semi-structured interviews. In particular, the attitude of stakeholders in Sweden, Denmark and Cyprus to sustainable building renovation/refurbishment is studied through three separate case studies. Within the framework of this study, it is identified that building physics and durability are the most important drivers for energy renovation. In Sweden, Denmark and Cyprus, these factors are contributed by maintenance, deterioration and moisture, respectively. The results of the questionnaires and semi-structured interviews presented herein provide an insight into the renovation process in the aforementioned countries and reveal that economy is not the most important driver for energy renovation. Instead, the results signify that drivers such as improvement of indoor air quality and elimination of moisture in the building envelope are of crucial importance. Moreover, the practical implications of this research explore and identify existing instruments for sustainable renovation and refurbishment.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
|
|
