| 1. |
- Nilsson, C. L., et al.
(författare)
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Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium
- 2013
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Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 12:1, s. 134-149
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Tidskriftsartikel (refereegranskat)abstract
- A first research development progress report of the Chromosome 19 Consortium with members from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-centric Human Proteome Project (C-HPP) global initiative, is presented (http://www.c-hpp.org). From the chromosome 19 peptide-targeted library constituting 6159 peptides, a pilot study was conducted using a subset with 125 isotope-labeled peptides. We applied an annotation strategy with triple quadrupole, ESI-Qtrap, and MALDI mass spectrometry platforms, comparing the quality of data within and in between these instrumental set-ups. LC–MS conditions were outlined by multiplex assay developments, followed by MRM assay developments. SRM was applied to biobank samples, quantifying kallikrein 3 (prostate specific antigen) in plasma from prostate cancer patients. The antibody production has been initiated for more than 1200 genes from the entire chromosome 19, and the progress developments are presented. We developed a dedicated transcript microarray to serve as the mRNA identifier by screening cancer cell lines. NAPPA protein arrays were built to align with the transcript data with the Chromosome 19 NAPPA chip, dedicated to 90 proteins, as the first development delivery. We have introduced an IT-infrastructure utilizing a LIMS system that serves as the key interface for the research teams to share and explore data generated within the project. The cross-site data repository will form the basis for sample processing, including biological samples as well as patient samples from national Biobanks.
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| 2. |
- Nanwani, Alisha, et al.
(författare)
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Augmenting the nickel-cobalt layered double hydroxide performance : Virtue of doping
- 2020
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Ingår i: Journal of Energy Storage. - : Elsevier BV. - 2352-152X .- 2352-1538. ; 31
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Tidskriftsartikel (refereegranskat)abstract
- Doping is the most effective strategy to improve the electrochemical performance of supercapacitors. Herein, we report the doping effect of Magnesium on structural instability of Ni-Co LDHs as the supercapacitor electrode material. The morphology of different compositions of magnesium are studied. The derived material with the Ni:Mg ratio of 1:1 displayed an excellent specific capacity of 624 Cg(-1) at current density of 10 Ag-1. Moreover, the specific capacity remained at 80% after 3000 cycles which suggest excellent cycle stability. An asymmetrc device was fabricated with N/M-2 as positive electrode and activated carbon cloth as negative electrode, which displayed a specific capacitance of 200 Fg(-1) at 0.25 Ag-1 with the energy density of 28 Whkg(-1). The device showed the capacitance retention of about 99% after 1000 cycles at 1 Ag-1. Therefore, improved structural
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