| 1. |
- Erripi, Kalliopi, et al.
(författare)
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Results of Mohs' Micrographic Surgery of Periocular Basal Cell Carcinoma: The Swedish Experience
- 2024
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Ingår i: ACTA DERMATO-VENEREOLOGICA. - 0001-5555 .- 1651-2057. ; 104
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Tidskriftsartikel (refereegranskat)abstract
- The Department of Ophthalmology, Sahlgrenska University Hospital, has until recently been the only eye clinic in the Nordic countries to perform Mohs' micrographic surgery of basal cell carcinoma. This has led to the practice of only the most complicated basal cell carcinomas being operated on with this technique. The purpose of this study was to present the results of these surgeries in patients with at least 5 years of follow-up. A retrospective study of all patients operated upon in 2010-2015 was performed. Data were gather ed from their medical charts. Primary outcome was recurrence of basal cell carcinoma. One -hundred and sixty-seven patients were operated on. Mohs' micrographic surgery was used for tumours that were judg ed as highly aggressive on preoperative biopsy, had ill-defined borders, had recurred after previous surgery, or a combination of these factors. Nine recurrences (5.4% of all radical Mohs' micrographic surgeries) were diagnosed after a mean postoperative time of 37 months (4-84 months). Interestingly, all of these 9 recurrences after Mohs' micrographic surgery were in patients who had such surgery because of a recurrent basal cell carcinoma to start with. Good results can be achieved when operating on the most complicated periocular basal cell carcinomas with Mohs' micrographic surgery but special care has to be taken to ensure radical borders when operating on recurring basal cell carcinomas.
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| 2. |
- Hashas, A. S. K., et al.
(författare)
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A new diagnostic method for retinal breaks in patients with posterior vitreous detachment: Ultra-wide-field imaging with the Zeiss Clarus 700
- 2023
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Ingår i: Acta Ophthalmologica. - : Wiley. - 1755-375X .- 1755-3768. ; 101:6, s. 627-635
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThis study was performed with the aim of finding a more convenient and less time-consuming method to diagnose retinal breaks in posterior vitreous detachment (PVD) patients. MethodsA prospective double-blind observational case study was performed with patients who were admitted to the Eye Emergency Department Sahlgrenska University Hospital with PVD symptoms and approved to participate in the study (n = 128). Standard slit lamp examination was compared with images from a Zeiss Clarus 700 ultra-wide-field camera (UWFC). Patients were examined and photographed by an independent operator. Data and image review was performed by three independent reviewers with varying experience. Retinal break detection with the two different methods (detailed eye examination by well-trained ophthalmologist and UWFC evaluations) was analysed statistically. ResultsAfter excluding diagnoses other than PVD as well as unclear images due to cataracts, vitreous bleeding, etc., a total of 103 eyes with PVD were evaluated. A total of 38 ruptures in 25 patients were detected by routine examination and were subjected to laser treatment. UWFC images were reviewed by three ophthalmology consultants and compared with routine examinations. Sensitivity values in detecting retinal ruptures in UWFC images of the three reviewers were 0.89, 0.87 and 0.79, and specificity values were 0.88, 0.86 and 0.93 (kappa values: 0.742, 0.689 and 0.728) respectively. ConclusionAlthough there have been rapid developments in imaging with UWFC in recent years and it is a very promising method for the future, routine clinical examination is still the only valid method for the detection of retinal tears today.
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| 3. |
- Svedberg, Karin, 1960
(författare)
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Outcome of eviscerations and enucleations at a Swedish tertiary referral centre between 2008 and 2019: improved surgical management leading to reduced complication rate
- 2023
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Ingår i: Orbit (London). - : Informa UK Limited. - 0167-6830 .- 1744-5108. ; 42:2, s. 174-180
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The aim of this study was to investigate the results of all eviscerations and enucleations performed at the Department of Ophthalmology, Sahlgrenska University Hospital, during 2008–2019 and to compare them with previously collected data from 1999 to 2007. Methods: This was a retrospective investigation using the medical records for all patients having had an evisceration or an enucleation at the Department of Ophthalmology, Sahlgrenska University Hospital, during the two defined periods of time. Main outcome measure was postoperative complications. Results: During 1999–2007, 181 surgeries were performed, 100 with implants, and 28/100 exposed implants and 9/100 removed implants were recorded during follow-up. During 2008–2019, 250 operations were performed with 158 implants, and there were 3/158 exposed implants and 2/158 extruded implants. Two ruptures of the surgical wound without implant exposure were noted, and one implant was exchanged. The reduction of exposed implants between the two periods was statistically significant (p <.001, Chi-square test). In enucleations, the use of one kind of porous polyethylene implant in the recent study period replaced a multitude of implants in the earlier study period. In eviscerations, the major change between the two study periods was the introduction of the split sclera technique and smaller implant size. Conclusion: The change in surgical technique between the two periods led to a significant reduction in implant-related complications.
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| 4. |
- Svedberg, Karin, 1960
(författare)
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Recurrence of primary acquired melanosis and conjunctival intraepithelial neoplasia
- 2023
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Ingår i: Ocular Oncology and Pathology. - : S. Karger AG. - 2296-4681 .- 2296-4657. ; 8:4-6, s. 236-241
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Tidskriftsartikel (refereegranskat)abstract
- IntroductionThe aim of this study was to investigate the frequency of recurrences, time to recurrence and which patients had a recurrence after treatment of conjunctival intraepithelial neoplasia (CIN), carcinoma in situ, and primary acquired melanosis (PAM) with atypia.MethodsA retrospective chart review of all patients included in the follow up program after completion of treatment for CIN or PAM with atypia on October 18, 2021, at the Department of Ophthalmology, Sahlgrenska University Hospital, was conducted.ResultsThere were five recurrences (5/31, 17%) in the group with CIN or carcinoma in situ. Two for patients with CIN grade II, and three for individuals with carcinoma in situ. Time to diagnosis of recurrence ranged from 6 to 288 months. No recurrence was diagnosed for the twenty-six patients followed after treatment for PAM with atypia.ConclusionWith the strategy of radical treatment of CIN and PAM with atypia whenever possible subsequent follow up can probably be ceased after ten years if the patient is not immunocompromised. For completely excised PAM with atypia grade I there is most likely no need for further clinical controls.
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| 5. |
- Svedberg, Karin, 1960
(författare)
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Så omhändertogs syn- eller ögonbesvär i primärvården.
- 2021
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Ingår i: Läkartidningen. - 0023-7205. ; 118, s. 1434-1437
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Tidskriftsartikel (refereegranskat)abstract
- Huvudbudskap • 1,5-2% av de som sökte på de aktuella vårdcentralerna sökte för syn/ögonbesvär. • Den vanligaste sökorsaken var ögonlocksrelaterad. • Synprövning användes i liten utsträckning som undersökningsmetod. • Färdigheten i undersökningsteknik behöver förbättras för många allmänläkare. • Den vanligaste diagnosen på vårdcentralen var infektiös konjunktivit. Lokalbehandling med antibiotika gavs till 87%. • 60% av patienterna slutbehandlades på vårdcentralen. • I denna studie remitterades 36% av patienterna vidare till ögonkliniken, i hälften av fallen utan specifik frågeställning.
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