| 1. |
|
|
| 2. |
|
|
| 3. |
- Cassinger, Cecilia, et al.
(författare)
-
Consuming place, contesting spatial imaginaries
- 2020
-
Ingår i: Research in Consumer Culture Theory. ; 3
-
Konferensbidrag (refereegranskat)abstract
- The last few years has seen the emergence of anti-consumption narratives (Chatzidakis and Lee, 2012; Cherrier, 2009), which contest the marketisation of places, and the way that property and space are currently organised by their exchange values, rather than use values (cf. Visconti et al., 2010). Anti-consumption acts disrupt key social imaginaries of places and are apparent in demonstrations and protests around the world related to macro societal issues, such as globalisation, climate crisis, migration, overtourism, and social inequalities (see Colomb and Novy, 2016). Such narratives do not only challenge the intensified commodification of space, but also the way that “socialities, subjectivities and spatialities are constituted in space” (Mansvelt, 2005, xvi). This special session extends previous research in consumer culture theory on how anti-consumption acts challenge established imaginaries of place (Chatzidakis et al., 2012; Chatzidakis and Lee, 2012; Visconti et al., 2010) by focusing on the performativity of spatial imaginaries. Spatial imaginaries are here thought of as collectively shared performative discourses that intervene and shape social reality via embodied, material practices (Watkins, 2015; Butler, 1993). The aim of the session is to examine spatial imaginaries that contest conventional strategies of organising places according to a consumerist logic for increased economic growth. The session focuses on spatial imaginaries that challenge the spatial status quo and provoke new ideas of what it means to inhabit places. Each of the three papers in the special session address the logics and consequences of spatial imaginaries for the practices and organisation of place in various ways. The first paper investigates how consumerist imaginaries of urban space are symbolically and materially reconsidered in citizens’ protests acts against the bourgeoning touristification of inner cities in Europe. Informed by a relational and material understanding of space and theories on the public sphere, the temporalities and spatialities of public protests are analysed as ways of re-gaining the lifeworld from the material and expressive colonialization of tourism-consumption. It is argued that in order to preserve the public sphere, urban governing strategies are shifting focus from spatial imaginaries of consumerism to imaginaries of the lived city of dwellers. The second paper problematizes the affective resonance and intensities of urban crowds, by exploring the role of individuals’ moods (anxiety, apathy, stress, rage and boredom) in enhancing or disturbing spatial atmospheres. It argues that diverse co-located and intersecting mobility practices create affective intensities that simultaneously carry the potential of the urban buzz and the risk of coalescing into enduring anomalies in spatial imaginaries. But where might spatial reimaginings take us? The third paper addresses this question with the concept of ’fourth space’ as a virtual space of ’possible places’. Virtual spaces are understood as a plethora of ‘possible spaces’, where it is possible to foresee alternative futures and inhabit revolutionary imaginaries.
|
|
| 4. |
- Emmerlich, Jens, 1974-, et al.
(författare)
-
Growth of Ti3SiC2 thin films by elemental target magnetron sputtering
- 2004
-
Ingår i: Journal of Applied Physics. - : AIP Publishing. - 0021-8979 .- 1089-7550. ; 96:9, s. 4817-4826
-
Tidskriftsartikel (refereegranskat)abstract
- Epitaxial Ti3SiC2(0001) thin films have been deposited by dc magnetron sputtering from three elemental targets of Ti, C, and Si onto MgO(111) and Al2O3(0001) substrates at temperatures of 800–900 °C. This process allows composition control to synthesize Mn + 1AXn (MAX) phases (M: early transition metal; A: A-group element; X: C and/or N; n = 1–3) including Ti4SiC3. Depositions on MgO(100) substrates yielding the Ti–Si–C MAX phases with (105), as the preferred orientation. Samples grown at different substrate temperatures, studied by means of transmission electron microscopy and x-ray diffraction investigations, revealed the constraints of Ti3SiC2 nucleation due to kinetic limitations at substrate temperatures below 700 °C. Instead, there is a competitive TiCx growth with Si segregation to form twin boundaries or Si substitutional incorporation in TiCx. Physical properties of the as-deposited single-crystal Ti3SiC2 films were determined. A low resistivity of 25 µ cm was measured. The Young's modulus, ascertained by nanoindentation, yielded a value of 343–370 GPa. For the mechanical deformation response of the material, probing with cube corner and Berkovich indenters showed an initial high hardness of almost 30 GPa. With increased maximum indentation loads, the hardness was observed to decrease toward bulk values as the characteristic kink formation sets in with dislocation ordering and delamination at basal planes.
|
|
| 5. |
- Kowal-Bielecka, Otylia, et al.
(författare)
-
Update of EULAR recommendations for the treatment of systemic sclerosis
- 2017
-
Ingår i: Annals of the Rheumatic Diseases. - : BMJ. - 0003-4967 .- 1468-2060. ; 76, s. 1327-1339
-
Tidskriftsartikel (refereegranskat)abstract
- The aim was to update the 2009 European League against Rheumatism (EULAR) recommendations for the treatment of systemic sclerosis (SSc), with attention to new therapeutic questions. Update of the previous treatment recommendations was performed according to EULAR standard operating procedures. The task force consisted of 32 SSc clinical experts from Europe and the USA, 2 patients nominated by the pan-European patient association for SSc (Federation of European Scleroderma Associations (FESCA)), a clinical epidemiologist and 2 research fellows. All centres from the EULAR Scleroderma Trials and Research group were invited to submit and select clinical questions concerning SSc treatment using a Delphi approach. Accordingly, 46 clinical questions addressing 26 different interventions were selected for systematic literature review. The new recommendations were based on the available evidence and developed in a consensus meeting with clinical experts and patients. The procedure resulted in 16 recommendations being developed (instead of 14 in 2009) that address treatment of several SSc-related organ complications: Raynaud's phenomenon (RP), digital ulcers (DUs), pulmonary arterial hypertension (PAH), skin and lung disease, scleroderma renal crisis and gastrointestinal involvement. Compared with the 2009 recommendations, the 2016 recommendations include phosphodiesterase type 5 (PDE-5) inhibitors for the treatment of SSc-related RP and DUs, riociguat, new aspects for endothelin receptor antagonists, prostacyclin analogues and PDE-5 inhibitors for SSc-related PAH. New recommendations regarding the use of fluoxetine for SSc-related RP and haematopoietic stem cell transplantation for selected patients with rapidly progressive SSc were also added. In addition, several comments regarding other treatments addressed in clinical questions and suggestions for the SSc research agenda were formulated. These updated data-derived and consensus-derived recommendations will help rheumatologists to manage patients with SSc in an evidence-based way. These recommendations also give directions for future clinical research in SSc.
|
|
| 6. |
- Lichrou, Maria, et al.
(författare)
-
Roundtable: Critical inquiries into places of consumption and consumption in places
- 2020
-
Ingår i: Research in Consumer Culture Theory. ; 3
-
Konferensbidrag (refereegranskat)abstract
- A growing body of consumer culture theory (CCT) research has pointed to the way that places are increasingly conceptualised and commodified as brands and consumption objects (Lichrou et al., 2008; Giovanardi et al., 2018). Research has explored consumers’ experiences with different kinds of spaces and places, including retail settings (e.g. Penaloza, 1998; Kozinets et al., 2004; Maclaran & Brown, 2005), natural and cultural attractions (e.g. Arnould and Price, 1993; Chronis et al., 2012), public (e.g. Visconti et al., 2010; Chatzidakis et al., 2012; O’Leary et al., 2019) and private places (e.g. Costa, 1989; Hirschmann et al., 2012) and virtual spaces (e.g. Denegri-Knott & Molesworth, 2010). Earlier accounts almost entirely focused on compartmentalised spaces and commercial arenas as containers of consumption, but more recent research examine the mutual constituency of consumption and space. For example, attention has turned to the interplay between consumers’ embodied spatial practices and the construction of place and space (Lucarelli & Giovanardi, 2016; O’Leary et al., 2019). However, further consideration of how consumer imaginaries and practices produce and transform places is called for (cf. Chatzidakis et al., 2018; Chatzidakis et al., 2012). Moreover, more consideration should be given to critical perspectives on the relational construction of consumption space.Places around the globe are currently reimagined as spaces of consumption (Miles, 2010, Massey, 2005), where sensations, dreams and play are mobilised with the sole aim of creating profit (Amin & Thrift, 2002). These processes often transform places into commodified and exlusionary spaces that can be detrimental for those living in them (Kearns & Philo, 1993, Lichrou et al., 2014; Kavaratzis et al., 2017). The commodifying logic of the economic politics of places diminishes the spaces where people lead their everyday life, make decisions, and cope with things other than the purely economic (Habermas, 1987). Such spaces are, as De Certeau (1984, 87) puts it, “haunted by countless ghosts that lurk there in silence to be “evoked” or not”. Yet, places are important sites of human activities beyond the commercial realm. The mobility of global capital, investments and growing volumes of international visitors and migrant labour have put these livehoods under multiple spatial and social pressures (ranging from crowding and environmental degradation to gentrification, and displacement), which has fuelled the upscaling of responsible or political consumerism and morally conscious policy agendas.This roundtable discussion brings together researchers representing different critical perspectives on place consumption. The aim is to provide an opportunity to talk about the meaning and implications of critical theory for the conceptualisation, analysis and collection of data regarding consumption in and of place (Chatzidakis et al., 2018) on multiple scales, ranging from micro-level practices to macro-level perspectives. More specifically, the discussion focuses on the conjunction of commodified and lived space, as well as on the complexities and social imaginaries arising in shared spaces. By virtue of the critical inquiry, the aim is to identify the empirical potential and conceptual possibilities embedded in such hybrid spaces, with regard to sustainable and inclusive place consumption and governance.
|
|
| 7. |
|
|
| 8. |
- Staff, Caroline, et al.
(författare)
-
Induction of IgM, IgA and IgE Antibodies in Colorectal Cancer Patients Vaccinated with a Recombinant CEA Protein
- 2012
-
Ingår i: Journal of Clinical Immunology. - : Springer Science and Business Media LLC. - 0271-9142 .- 1573-2592. ; 32:4, s. 855-865
-
Tidskriftsartikel (refereegranskat)abstract
- Previous clinical studies have indicated that natural IgM antibodies have the ability to induce apoptosis of tumor cells but IgE and IgA may also mediate tumor cell killing (in addition to IgG). The aim of the study was to analyse induction of IgM, IgA and IgE antibodies in patients vaccinated with the tumor associated antigen CEA. Twenty-four resected CRC patients without macroscopic disease were immunized seven times with CEA +/- GM-CSF. Four different dose schedules were used over a 12-month period. IgM, IgA and IgE antibody responses against recombinant CEA were determined by ELISA. Patients were monitored immunologically for 36 months and clinically for 147 months. GM-CSF significantly augmented the anti-CEA response for all three antibody classes. Low dose of CEA tended to induce a higher IgM, IgA or IgE anti-CEA antibody response than higher. Anti-CEA IgA antibodies could lyse CEA positive tumor cells in antibody dependent cellular cytotoxicity (ADCC) as well as in complement dependent cytotoxicity (CDC). A significant correlation between survival and high IgA anti-CEA titers was noted (p = 0.02) irrespective of GM-CSF treatment. The observation that IgA anti-CEA antibodies were cytotoxic and associated with improved survival might indicate that also these antibodies may exert a clinical anti-tumor effect.
|
|
