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- Lorente, A. Sanchez, et al.
(författare)
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Performance of HPGe detectors in high magnetic fields
- 2007
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 573:3, s. 410-417
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Tidskriftsartikel (refereegranskat)abstract
- A new generation of high-resolution hypernuclear gamma-spectroscopy experiments with high-purity germanium detectors (HPGe) are presently designed at the FINUDA spectrometer at DA Phi NE, the Frascati phi-factory, and at (P) over bar ANDA, the (p) over barp hadron spectrometer at the future FAIR facility. Both, the FINUDA and (P) over bar ANDA spectrometers are built around the target region covering a large solid angle. To maximise the detection efficiency the HPGe detectors have to be located near the target, and therefore they have to be operated in strong magnetic fields (B approximate to I T). The performance of HPGe detectors in such an environment has not been well investigated so far. In the present work VEGA and EUROBALL Cluster HPGe detectors were tested in the field provided by the ALADiN magnet at GSI. No significant degradation of the energy resolution was found, and a change in the rise time distribution of the pulses from preamplifiers was observed. A correlation between rise time and pulse height was observed and is used to correct the measured energy, recovering the energy resolution almost completely. Moreover, no problems in the electronics due to the magnetic field were observed.
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| 5. |
- Szymanska, K., et al.
(författare)
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Resolution, efficiency and stability of HPGe detector operating in a magnetic field at various gamma-ray energies
- 2008
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 592:3, s. 486-492
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Tidskriftsartikel (refereegranskat)abstract
- The use of High Purity Germanium detectors (HPGe) has been planned in some future experiments of hadronic physics. The crystals will be located close to large spectrometers where the magnetic fringing field will not be negligible and their performances might change. Moreover high precision is required in these experiments. The contribution of magnetic field presence and long term measurements is unique. In this paper the results of systematic measurements of the resolution, stability and efficiency of a crystal operating inside a magnetic field of 0.8 T, using radioactive sources in the energy range from 0.08 to 1.33 MeV, are reported. The measurements have been repeated during several months in order to test if any permanent damage occurred. The resolution at 1.117 and 1.332 MeV gamma-rays from a Co-60 source has been measured at different magnetic fields in the range of 0-0.8 T and the results are compared with the previous data.
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| 6. |
- Brookes, Paul, et al.
(författare)
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Critical slowing down in circuit quantum electrodynamics
- 2021
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Ingår i: Science advances. - : American Association for the Advancement of Science (AAAS). - 2375-2548. ; 7:21
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Tidskriftsartikel (refereegranskat)abstract
- Critical slowing down of the time it takes a system to reach equilibrium is a key signature of bistability in dissipative first-order phase transitions. Understanding and characterizing this process can shed light on the underlying many-body dynamics that occur close to such a transition. Here, we explore the rich quantum activation dynamics and the appearance of critical slowing down in an engineered superconducting quantum circuit. Specifically, we investigate the intermediate bistable regime of the generalized Jaynes-Cummings Hamiltonian (GJC), realized by a circuit quantum electrodynamics (cQED) system consisting of a transmon qubit coupled to a microwave cavity. We find a previously unidentified regime of quantum activation in which the critical slowing down reaches saturation and, by comparing our experimental results with a range of models, we shed light on the fundamental role played by the qubit in this regime.
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| 10. |
- Szymanska, E., et al.
(författare)
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Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers - antiherpes activity and penetration behavior across the human vaginal epithelium
- 2021
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Ingår i: Drug Delivery. - : Informa UK Limited. - 1071-7544 .- 1521-0464. ; 28:1, s. 2278-2288
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Tidskriftsartikel (refereegranskat)abstract
- Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit carriers with zidovudine (ZVD) as a model antiretroviral agent in contact with excised human vaginal epithelium followed with an examination of in vitro antiherpes activity in immortal human keratinocytes HaCaT and human vaginal epithelial cells VK2-E6/E7. Both ZVD dispersion and placebo microparticles served as controls. Microparticles displayed feasible (comparable to commercial vaginal product) mucoadhesive and mucoretention characteristics to isolated human vaginal tissue. Ex vivo penetration studies revealed that gCS increased the accumulation of active agent in the vaginal epithelium but surprisingly did not facilitate its penetration across human tissue. Finally, the obtained antiviral results demonstrated the potential of gCS as an antiherpes adjunctive, whose mode of action was related to blocking viral attachment.
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