| 1. |
- Takahashi, Kazue, et al.
(författare)
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Propagation of Ultralow-Frequency Waves from the Ion Foreshock into the Magnetosphere During the Passage of a Magnetic Cloud
- 2021
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Ingår i: Journal of Geophysical Research - Space Physics. - : American Geophysical Union (AGU). - 2169-9380 .- 2169-9402. ; 126:2
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Tidskriftsartikel (refereegranskat)abstract
- We have examined the properties of ultralow-frequency (ULF) waves in space (the ion foreshock, magnetosheath, and magnetosphere) and at dayside magnetometer stations (L = 1.6-6.5) during Earth's encounter with a magnetic cloud in the solar wind, which is characterized by magnetic fields with large magnitudes (similar to 14 nT) and small cone angles (similar to 30 degrees). In the foreshock, waves were excited at similar to 90 m Hz as expected from theory, but there were oscillations at other frequencies as well. Oscillations near 90 mHz were detected at the other locations in space, but they were not in general the most dominant oscillations. On the ground, pulsations in the approximate Pc2-Pc4 band (5 mHz-120 mHz) were continuously detected at all stations, with no outstanding spectral peaks near 90 mHz in the H component except at stations where the frequency of the third harmonic of standing Alfven waves had this frequency. The fundamental toroidal wave frequency was below 90 mHz at all stations. In the D component spectra, a minor spectral peak is found near 90 mHz at stations located at L < 3, and the power dropped abruptly above this frequency. Magnetospheric compressional wave power was much weaker on the nightside. A hybrid-Vlasov simulation indicates that foreshock ULF waves have short spatial scale lengths and waves transmitted into the magnetosphere are strongly attenuated away from noon.
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| 2. |
- Hoshino, Ayuko, et al.
(författare)
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
- 2020
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Ingår i: Cell. - : CELL PRESS. - 0092-8674 .- 1097-4172. ; 182:4, s. 1044-
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Tidskriftsartikel (refereegranskat)abstract
- There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in 426 human samples from tissue explants (TEs), plasma, and other bodily fluids. Among traditional exosome markers, CD9, HSPA8, ALIX, and HSP90AB1 represent pan-EVP markers, while ACTB, MSN, and RAP1B are novel pan-EVP markers. To confirm that EVPs are ideal diagnostic tools, we analyzed proteomes of TE- (n =151) and plasma-derived (n =120) EVPs. Comparison of TE EVPs identified proteins (e.g., VCAN, TNC, and THBS2) that distinguish tumors from normal tissues with 90% sensitivity/94% specificity. Machine-learning classification of plasma-derived EVP cargo, including immunoglobulins, revealed 95% sensitivity/90% specificity in detecting cancer Finally, we defined a panel of tumor-type-specific EVP proteins in TEs and plasma, which can classify tumors of unknown primary origin. Thus, EVP proteins can serve as reliable biomarkers for cancer detection and determining cancer type.
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| 3. |
- Imamura, Teruhiko, et al.
(författare)
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A case with recovery of response to tolvaptan associated with remission of acute kidney injury and increased urine osmolality
- 2013
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Ingår i: International Heart Journal. - : International Heart Journal Association. - 1349-2365 .- 1349-3299. ; 54:2, s. 115-118
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Tidskriftsartikel (refereegranskat)abstract
- Tolvaptan (TLV), a vasopressin type 2 receptor antagonist, has been demonstrated to be effective in patients with decompensated heart failure (HF) refractory to incremental doses of diuretics, but the responsiveness has not always been predictable. We have recently proposed that urine osmolality (U-OSM) is a valuable parameter for the prediction of responses to TLV, because U-OSM reflects the activity of the collecting ducts, where TLV plays its unique role. Acute kidney injury (AKI) is often associated with severe tubular dysfunction, including the collecting ducts, and in such cases a response to TLV may not be expected. We here experienced a patient with HF and AKI in whom TLV was not effective during AKI. We also observed recovery of responsiveness to TLV along with remission of AKI as well as increased U-OSM later on. We believe that this is the first report on the reversibility of the TLV response in relation to U-OSM.
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| 5. |
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| 6. |
- Takahashi, Wakana, et al.
(författare)
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Waste sorting/disposal habits in Swedish households : Relations with facilities, gender and knowledge of waste treatment [in Japanese]
- 2013
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Ingår i: Journal of the Faculty of International Studies, Utsunomiya University. - 1342-0364. ; 36, s. 1-16
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Tidskriftsartikel (refereegranskat)abstract
- A survey on household waste sorting and disposal habits was conducted in Sweden to investigate behavioral patterns of recycling in a context in which wide measures are taken to promote and encourage pro-environmental behavior by making it easy and convenient. 207 residents of three cities in southern Sweden, Lund, Malmö and Helsingborg, responded to an online questionnaire survey. Relations between waste sorting/disposing habits with facilities, gender and knowledge of waste treatment were analyzed with some emphasis on food waste sorting. Recycling rates were generally high and reasons for sorting indicated that food waste sorting was a norm-based behavior. However, there were also indications that convenience was a precondition. Recycling rates were higher when dedicated containers for disposing (recycling) items were provided and the collection point was closer. There was a striking gender difference in food waste sorting. Single male households did not sort food waste at all while more than 90% of other groups did when provided the collection service. This was interpreted as differences in lifestyles rather than attitudes based on other data. Relations between recycling rates with house-ownership and knowledge of waste treatment fees were found and effects of reference groups were also suggested. The authors plan to replicate the survey in Japan to compare the results and draw implications for designing policies, services and environments for promoting waste sorting/recycling.
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| 7. |
- Yabuta, Hikaru, et al.
(författare)
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Macromolecular organic matter in samples of the asteroid (162173) Ryugu
- 2023
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Ingår i: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 379:6634
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Tidskriftsartikel (refereegranskat)abstract
- Samples of the carbonaceous asteroid (162173) Ryugu were collected and brought to Earth by the Hayabusa2 spacecraft. We investigated the macromolecular organic matter in Ryugu samples and found that it contains aromatic and aliphatic carbon, ketone, and carboxyl functional groups. The spectroscopic features of the organic matter are consistent with those in chemically primitive carbonaceous chondrite meteorites that experienced parent-body aqueous alteration (reactions with liquid water). The morphology of the organic carbon includes nanoglobules and diffuse carbon associated with phyllosilicate and carbonate minerals. Deuterium and/or nitrogen-15 enrichments indicate that the organic matter formed in a cold molecular cloud or the presolar nebula. The diversity of the organic matter indicates variable levels of aqueous alteration on Ryugus parent body.
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