| 1. |
- Talibov, Madar, et al.
(författare)
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Estimation of occupational cosmic radiation exposure among airline personnel : Agreement between a job-exposure matrix, aggregate, and individual dose estimates
- 2017
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Ingår i: American Journal of Industrial Medicine. - : WILEY. - 0271-3586 .- 1097-0274. ; 60:4, s. 386-393
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundJob-exposure matrices (JEM) are used for exposure assessment in occupational studies, but they can involve errors. We assessed agreement between the Nordic Occupational Cancer Studies JEM (NOCCA-JEM) and aggregate and individual dose estimates for cosmic radiation exposure among Finnish airline personnel. MethodsCumulative cosmic radiation exposure for 5,022 airline crew members was compared between a JEM and aggregate and individual dose estimates. ResultsThe NOCCA-JEM underestimated individual doses. Intraclass correlation coefficient was 0.37, proportion of agreement 64%, kappa 0.46 compared with individual doses. Higher agreement was achieved with aggregate dose estimates, that is annual medians of individual doses and estimates adjusted for heliocentric potentials. ConclusionsThe substantial disagreement between NOCCA-JEM and individual dose estimates of cosmic radiation may lead to exposure misclassification and biased risk estimates in epidemiological studies. Using aggregate data may provide improved estimates. Am. J. Ind. Med. 60:386-393, 2017.
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| 2. |
- Talibov, Madar, et al.
(författare)
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Occupation and Leukemia in Nordic Countries
- 2012
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Ingår i: Journal of Occupational and Environmental Medicine. - : LIPPINCOTT WILLIAMS & WILKINS. - 1076-2752 .- 1536-5948. ; 54:12, s. 1527-1532
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Tidskriftsartikel (refereegranskat)abstract
- Objective: We studied occupational variation of the risk of acute myeloid leukemia, chronic lymphocytic leukemia, and other leukemia in Nordic countries. Methods: The study cohort comprised 15 million persons older than 30 years who participated in the population censuses in 1960, 1970, 1980/1981, 1990, or all of these years in five Nordic countries. Standardized incidence ratios (SIRs) were estimated for 53 occupations and one group of economically inactive persons. Results: Significantly increased risks were observed for acute myeloid leukemia among drivers (SIR = 1.16; 95% confidence interval [CI], 1.07-1.26) and food workers (SIR = 1.13; 95% CI, 1.01-1.27); for chronic lymphocytic leukemia among farmers (SIR = 1.09; 95% CI, 1.04-1.14) and clerical workers (SIR = 1.07; 95% CI, 1.01-1.14); and for other leukemia among seamen (SIR = 1.24; 95% CI, 1.04-1.49), "other health workers" (SIR = 1.22; 95% CI, 1.02-1.47), chemical process workers (SIR = 1.18; 95% CI, 1.01-1.38), and sales agents (SIR = 1.15; 95% CI, 1.06-1.25). Conclusion: Observed modest occupational variation of leukemia risk might be associated with occupational or lifestyle factors.
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| 3. |
- Talibov, Madar, et al.
(författare)
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Occupational exposure to solvents and acute myeloid leukemia : a population-based, case-control study in four Nordic countries
- 2014
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Ingår i: Scandinavian Journal of Work, Environment and Health. - : SCANDINAVIAN JOURNAL WORK ENVIRONMENT & HEALTH. - 0355-3140 .- 1795-990X. ; 40:5, s. 511-517
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Tidskriftsartikel (refereegranskat)abstract
- Objective The aim of the current study was to assess the relation between occupational exposure to solvents and the risk of acute myeloid leukemia (AML). Methods Altogether, this study comprises 15 332 incident cases of AML diagnosed in Finland, Norway, Sweden, and Iceland from 1961-2005 and 76 660 controls matched by year of birth, sex, and country. Occupational records were linked with Nordic Occupational Cancer Study job exposure matrix (JEM) to estimate quantitative values for 26 occupational exposure factors. Hazard ratios (HR) with 95% confidence intervals (95% CI) were estimated by using conditional logistic regression models. Results We did not observe statistically significantly increased risk for exposure to any of the solvents. HR estimates for high levels of toluene (HR 1.35, 95% CI 0.74-2.46), aromatic hydrocarbon solvents (ARHC) (HR 1.18, 95% CI 0.76-1.86), and moderate-to-high levels of trichloroethylene were slightly but non-significantly elevated. We did not observe an association between benzene exposure and AML in this study. Conclusions This study did not provide clear evidence for an association between occupational solvent exposure and AML. There was some indication for an excess risk in the groups of workers exposed to toluene, trichloroethylene, and ARHC.
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