| 1. |
|
|
| 2. |
- Carpman, Nicole
(författare)
-
Marine Current Resource Assessment : Measurements and Characterization
- 2015
-
Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The increasing interest in converting energy from renewable resources into electricity has led to an increase in research covering the field of marine current energy, mainly concerning tidal currents and in-stream tidal turbines. Tides have the advantage of being predictable decades ahead. However, the tidal resource is intermittent and experiences local variations that affect the power output from a conversion system. The variability is mainly due to four aspects: the tidal regime, the tidal cycle, bathymetry at the site and weather effects. Each potential site is unique, the velocity flow field at tidal sites is highly influenced by local bathymetry and turbulence. Hence, characterizing the resource requires careful investigations and providing high quality velocity data from measurement surveys is of great importance. In this thesis, measurements of flow velocities have been performed at three kinds of sites.A tidal site has been investigated for its resource potential in one of all of the numerous fjords in Norway. Measurements have been performed to map the spatial and temporal variability of the resource. Results show that currents in the order of 2 m/s are present in the center of the channel. Furthermore, the flow is highly bi-directional between ebb and flood flows. The site thus have potential for in-stream energy conversion. A model is proposed that predicts peak current speed from information on tidal range at the site. A corresponding model can be set up and implemented at other similar sites affected by tides, i.e. fjord inlets connecting the ocean to a fjord or a basin.A river site serves as an experimental site for a marine current energy converter that has been designed at Uppsala University and deployed in Dalälven, Söderfors. The flow rate at the site is regulated by an upstream hydrokinetic power plant nearby, making the site suitable for experiments on the performance of the vertical axis turbine in its natural environment. The turbine has been run in uniform flow and measurements have been performed to characterize the extent of the wake.An ocean current site was a target of investigation for its potential for providing utilizable renewable energy. A measurement campaign was conducted, mapping the flow both spatially and temporally. However, the site was shown to not be suitable for energy conversion using present technique.
|
|
| 3. |
- Forslund, Johan, 1985-
(författare)
-
Experimental Results of a Load-Controlled Vertical Axis Marine Current Energy Converter
- 2015
-
Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis investigates the load control of a marine current energy converter using a vertical axis turbine mounted on a permanent magnet synchronous generator. The purpose of this thesis is to show the work done in the so far relatively uncharted territory of control systems for hydro kinetic energy conversion. The work is in its early stage and is meant to serve as a guide forfuture development of the control system.An experimental power station has been deployed and the first results are presented.A comparison between three load control methods has been made; a fixedAC load, a fixed pulse width modulated DC load and a DC bus voltage control of a DC load. Experimental results show that the DC bus voltage control reduces the variation of rotational speed with a factor of 3.5. For all three cases, the tip speed ratio of the turbine can be kept close to the expected optimal tip speed ratio. However, for all three cases the average extracted power was significantly lower than the average power available in the turbine times the estimated maximum power coefficient. A maximum power point tracking system, with or without water velocity measurement, should increase the average extracted power.A simulation model has been validated using experimental data. The simulated system consists of the electrical system and a hydrodynamic vortex model for the turbine. Experiments of no load operation were conducted to calibrate the drag losses of the turbine. Simulations were able to predict the behaviour in a step response for a change in tip speed ratio when the turbine was operated close to optimal tip speed ratio. The start position of the turbine was varied in the simulation to view the influence on the step response from a changed turbine position relative to the direction of the water flow.
|
|
| 4. |
- Thomas, Karin, 1977-
(författare)
-
Low Speed Energy Conversion from Marine Currents
- 2007
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The focus of this thesis is research on the performance of very low speed direct drive permanent magnet generators for energy conversion from marine and tidal currents. Various aspects involved in the design of these generators and their electromagnetic modelling using the finite element simulations are presented. For a detailed study, a 5 kW prototype generator has been designed and constructed based on finite element based simulations. Several experiments were conducted on the prototype generator. The experimental results were compared with the corresponding case simulations on the designed generator. The differences between the results predicted by the simulations and those predicted by the measurements were less than 10%. The part and overload performance of the generator has been investigated and it is found from both simulations and measurements that the generator is capable to efficiently operate at varying speeds. The tests on the experimental generator were made for speeds between 2 and 16 rpm and for load variations of 0.5 to 2 per unit. In this thesis it is shown that it is possible to design a very low speed direct drive generator for more or less any given marine current site and this is beneficial for projects aiming to develop a technical and economical viable marine current energy conversion system.
|
|
| 5. |
- Wadensten, Elisabeth, et al.
(författare)
-
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer
- 2023
-
Ingår i: JCO Precision Oncology. - : American Society of Clinical Oncology. - 2473-4284. ; :7
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in selected high-risk cases. However, the extent to which such characterization offers clinically actionable data in a prospective broadly inclusive setting remains largely unexplored.Methods: We implemented prospective whole-genome sequencing (WGS) of tumor and germline, complemented by whole-transcriptome sequencing (RNA-Seq) for all children diagnosed with a primary or relapsed solid malignancy in Sweden. Multidisciplinary molecular tumor boards were set up to integrate genomic data in the clinical decision process along with a medicolegal framework enabling secondary use of sequencing data for research purposes.Results: During the study's first 14 months, 118 solid tumors from 117 patients were subjected to WGS, with complementary RNA-Seq for fusion gene detection in 52 tumors. There was no significant geographic bias in patient enrollment, and the included tumor types reflected the annual national incidence of pediatric solid tumor types. Of the 112 tumors with somatic mutations, 106 (95%) exhibited alterations with a clear clinical correlation. In 46 of 118 tumors (39%), sequencing only corroborated histopathological diagnoses, while in 59 cases (50%), it contributed to additional subclassification or detection of prognostic markers. Potential treatment targets were found in 31 patients (26%), most commonly ALK mutations/fusions (n = 4), RAS/RAF/MEK/ERK pathway mutations (n = 14), FGFR1 mutations/fusions (n = 5), IDH1 mutations (n = 2), and NTRK2 gene fusions (n = 2). In one patient, the tumor diagnosis was revised based on sequencing. Clinically relevant germline variants were detected in 8 of 94 patients (8.5%).Conclusion: Up-front, large-scale genomic characterization of pediatric solid malignancies provides diagnostically valuable data in the majority of patients also in a largely unselected cohort.
|
|
