| 1. |
- Threadgold, J, et al.
(författare)
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The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease
- 2002
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Ingår i: Gut. - : BMJ. - 1468-3288 .- 0017-5749. ; 50:5, s. 675-681
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Tidskriftsartikel (refereegranskat)abstract
- Background: Mutations in the PRSS1 gene explain most occurrences of hereditary pancreatitis (HP) but many HP families have no PRSS1 mutation. Recently, an association between the mutation N34S in the pancreatic secretary trypsin inhibitor (SPINK1 or PSTI) gene and idiopathic chronic pancreatitis (ICP) was reported. It is unclear whether the N34S mutation is a cause of pancreatitis per se, whether it modifies the disease, or whether it is a marker of the disease. Patients and methods: A total of 327 individuals from 217 families affected by pancreatitis were tested: 152 from families with HP, 108 from families with ICP, and 67 with alcohol related CP (ACP). Seven patients with ICP had a family history of pancreatitis but no evidence of autosomal dominant disease (f-ICP) compared with 87 patients with true ICP (t-ICP). Two hundred controls were also tested for the N34S mutation. The findings were related to clinical outcome. Results: The N34S mutation was carried by five controls (2.5%; allele frequency 1.25%), 11/87 (13%) t-ICP patients (p=0.0013 v controls), and 6/7 (86%) affected (p<0.0001 v controls) and 1/9 (11%) unaffected f-ICP cases. N34S was found in 4/108 affected HP patients (p=0.724 v controls), in, 3/27 (11%) with wild-type and in 1/81 (1%) with mutant PRSS1, and 4/67 ACP patients (all p>0.05 v controls). The presence of the N34S mutation was not associated with early disease onset or disease severity. Conclusions: The prevalence of the N34S mutation was increased in patients with ICP and was greatest in f-ICP cases. Segregation of the N34S mutation in families with pancreatitis is unexplained and points to a complex association between N34S and another putative pancreatitis related gene.
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| 2. |
- Sebalo, Ivan, et al.
(författare)
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Conspiracy theories: why they are believed and how they can be challenged
- 2023
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Ingår i: Journal of Cognitive Psychology. - : Taylor & Francis. - 2044-5911 .- 2044-592X. ; 35:4, s. 383-400
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Tidskriftsartikel (refereegranskat)abstract
- The current study aimed: (i) to identify personal characteristics associated with endorsing conspiracy theories; and (ii) to investigate methods for dispelling conspiracy beliefs. Participants were shown a single conspiracy theory and they also completed questionnaires about their reasoning skills, types of information processing (System 1 vs. System 2), endorsement of paranormal beliefs, locus of control and pattern perception. To challenge the endorsement of the conspiracy, participants read either: (i) neutral information; (ii) a critical analysis of the vignette; (iii) a critical analysis of the vignette with discussion of realistic consequences; or (iv) a critical analysis of the vignette with “feeling of control” priming. Only addressing the consequences of the conspiracy theory decreased its endorsement. Furthermore, only type of information processing and belief in paranormal phenomena, were associated with endorsement of the conspiracy. These findings are discussed in relation to previous studies and theories of conspiratorial ideation.
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| 3. |
- Andersson, Hanna, 1991-, et al.
(författare)
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The negative footprint illusion is exacerbated by the numerosity of environment-friendly additions: unveiling the underpinning mechanisms
- 2024
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Ingår i: Journal of Cognitive Psychology. - : Taylor & Francis. - 2044-5911 .- 2044-592X. ; 36:2, s. 295-307
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Tidskriftsartikel (refereegranskat)abstract
- The addition of environmentally friendly items to conventional items sometimes leads people to believe that the carbon footprint of the entire set decreases rather than increases. This negative footprint illusion is supposedly underpinned by an averaging bias: people base environmental impact estimates not on the total impact of items but on their average. Here, we found that the illusion's magnitude increased with the addition of a greater number of "green" items when the number of conventional items remained constant (Studies 1 and 2), supporting the averaging-bias account. We challenged this account by testing what happens when the number of items in the conventional and "green" categories vary while holding the ratio between the two categories constant (Study 3). At odds with the averaging-bias account, the magnitude of the illusion increased as the category size increased, revealing a category-size bias, and raising questions about the interplay between these biases in the illusion.
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| 4. |
- Ball, Linden J., et al.
(författare)
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The effects of stimulus complexity and conceptual fluency on aesthetic judgments of abstract art : Evidence for a default–interventionist account
- 2018
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Ingår i: Metaphor and Symbol. - : Routledge. - 1092-6488 .- 1532-7868. ; 33:3, s. 235-252
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Tidskriftsartikel (refereegranskat)abstract
- We report an experiment investigating how stimulus complexity and conceptual fluency (i.e., the ease of deriving meaning) influence aesthetic liking judgments for abstract artworks. We presented participants with paintings at two levels of complexity (high vs. low) and five levels of conceptual fluency (determined from a prior norming study) and requested separate ratings of beauty and creativity. Our predictions were derived from the PIA Model (Pleasure-Interest Model of Aesthetic Liking), which views aesthetic preferences as being formed by two, distinct fluency-based processes: an initial, automatic, stimulus-driven, default process and a subsequent, perceiver-driven deliberative process. A key trigger for deliberative processing is assumed to be disfluency at the default stage, as caused by factors such as visual complexity. We predicted that complexity and conceptual fluency would interact in determining aesthetic liking, with people preferring complex stimuli, but only when these are relatively easy to process conceptually. Our results supported this prediction for beauty judgments, although creativity judgments showed a curiously uniform profile. Nevertheless, the predictive capacity of the PIA Model in relation to beauty judgments attests to the explanatory strength of this default?interventionist theory of aesthetic liking. We conclude by noting important parallels between the PIA Model and the Revised Optimal Innovation Hypothesis, which likewise has broad reach in explaining how defaultness and non-defaultness affect pleasure across a range of linguistic and pictorial stimuli.
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| 5. |
- Marsh, John E., et al.
(författare)
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Chatting in the Face of the Eyewitness : The Impact of Extraneous Cell-Phone Conversation on Memory for a Perpetrator
- 2017
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Ingår i: Canadian journal of experimental psychology. - : American Psychological Association (APA). - 1196-1961 .- 1878-7290. ; 71:3, s. 183-190
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Tidskriftsartikel (refereegranskat)abstract
- Cell-phone conversation is ubiquitous within public spaces. The current study investigates whether ignored cell-phone conversation impairs eyewitness memory for a perpetrator. Participants viewed a video of a staged crime in the presence of 1 side of a comprehensible cell-phone conversation (meaningful halfalogue), 2 sides of a comprehensible cell-phone conversation (meaningful dialogue), 1 side of an incomprehensible cell-phone conversation (meaningless halfalogue), or quiet. Between 24 and 28 hr later, participants freely described the perpetrator's face, constructed a single composite image of the perpetrator from memory, and attempted to identify the perpetrator from a sequential lineup. Further, participants rated the likeness of the composites to the perpetrator. Face recall and lineup identification were impaired when participants witnessed the staged crime in the presence of a meaningful halfalogue compared to a meaningless halfalogue, meaningful dialogue, or quiet. Moreover, likeness ratings showed that the composites constructed after ignoring the meaningful halfalogue resembled the perpetrator less than did those constructed after experiencing quiet or ignoring a meaningless halfalogue or a meaningful dialogue. The unpredictability of the meaningful content of the halfalogue, rather than its acoustic unexpectedness, produces distraction. The results are novel in that they suggest that an everyday distraction, even when presented in a different modality to target information, can impair the long-term memory of an eyewitness.
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| 6. |
- Marsh, John E., et al.
(författare)
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The susceptibility of compound remote associate problems to disruption by irrelevant sound : a Window onto the component processes underpinning creative cognition?
- 2021
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Ingår i: Journal of Cognitive Psychology. - : Taylor & Francis. - 2044-5911 .- 2044-592X. ; 33:6-7, s. 793-822
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Tidskriftsartikel (refereegranskat)abstract
- Controversy exists regarding the processes involved in creative thinking with the Remote Associates Test (RAT) and the Compound Remote Associates Test (CRAT). We report three experiments that aimed to shed light on the component processes underpinning CRAT performance by using the mere presence of task-irrelevant sound as a key theoretical tool. Experiments 1 and 2 revealed that CRAT performance was impaired relative to a quiet condition by the presence of sequences of changing letters and tones, respectively. In both experiments a non-changing sound (a repeated letter or a repeated tone) produced no disruption relative to quiet. Experiment 3 established that additional disruption was engendered by having to ignore meaningful speech as compared to meaningless speech. These experiments demonstrate that both semantic activation and subvocalisation are important determinants of successful creative thinking with CRAT problems. We suggest that semantic activation underpins solution-generation processes whereas subvocalisation underpins solution-evaluation processes.
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| 7. |
- Threadgold, Emma, et al.
(författare)
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Background music stints creativity : evidence from compound remote associate tasks
- 2019
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Ingår i: Applied Cognitive Psychology. - : John Wiley & Sons. - 0888-4080 .- 1099-0720. ; 33:5, s. 873-888
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Tidskriftsartikel (refereegranskat)abstract
- Summary Background music has been claimed to enhance people's creativity. In three experiments, we investigated the impact of background music on performance of Compound Remote Associate Tasks (CRATs), which are widely thought to tap creativity. Background music with foreign (unfamiliar) lyrics (Experiment 1), instrumental music without lyrics (Experiment 2), and music with familiar lyrics (Experiment 3) all significantly impaired CRAT performance in comparison with quiet background conditions. Furthermore, Experiment 3 demonstrated that background music impaired CRAT performance regardless of whether the music induced a positive mood or whether participants typically studied in the presence of music. The findings challenge the view that background music enhances creativity and are discussed in terms of an auditory distraction account (interference-by-process) and the processing disfluency account.
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| 8. |
- Threadgold, Emma, et al.
(författare)
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Normative data for 84 UK English rebus puzzles
- 2018
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Ingår i: Frontiers in Psychology. - : Frontiers Media S.A.. - 1664-1078. ; 9
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Tidskriftsartikel (refereegranskat)abstract
- Recent investigations have established the value of using rebus puzzles in studying the insight and analytic processes that underpin problem solving. The current study sought to validate a pool of 84 rebus puzzles in terms of their solution rates, solution times, error rates, solution confidence, self-reported solution strategies, and solution phrase familiarity. All of the puzzles relate to commonplace English sayings and phrases in the United Kingdom. Eighty-four rebus puzzles were selected from a larger stimulus set of 168 such puzzles and were categorized into six types in relation to the similarity of their structures. The 84 selected problems were thence divided into two sets of 42 items (Set A and Set B), with rebus structure evenly balanced between each set. Participants (N = 170; 85 for Set A and 85 for Set B) were given 30 s to solve each item, subsequently indicating their confidence in their solution and self-reporting the process used to solve the problem (analysis or insight), followed by the provision of ratings of the familiarity of the solution phrases. The resulting normative data yield solution rates, error rates, solution times, confidence ratings, self-reported strategies and familiarity ratings for 84 rebus puzzles, providing valuable information for the selection and matching of problems in future research.
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