| 1. |
- Cai, Shengyun, et al.
(författare)
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Photo-stable substituted dihydroindolo[2,3-b]carbazole-based organic dyes : tuning the photovoltaic properties by optimizing the pi structure for panchromatic DSSCs
- 2014
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Ingår i: Tetrahedron. - : Elsevier BV. - 0040-4020 .- 1464-5416. ; 70:43, s. 8122-8128
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Tidskriftsartikel (refereegranskat)abstract
- Three dihydroindolo[2,3-b]carbazole (DDC) donor based organic dyes (DDC6-DDC8) with long conjugated systems were successfully synthesized and characterized by optical, electrochemical, computational analysis, and photovoltaic methods. It was found that the elongated pi system as well as the high molar extinction coefficients (4.2-5.3 M-1 cm(-1)) sufficiently reinforced the light harvesting ability with the IPCE response of one dye DDC8 extended to 850 nm, which resulted in large J(sc) of these dyes based devices (high as 16.41 mA cm(-2)). The attached alkyl chains suppress the dark current to some extent, resulting the DDC6 and DDC7 devices in high V-oc, while DDC8 displayed low V-oc, because BTD in DDC8 could attract the iodine ion, which could accelerate the charge recombination. Among the three dyes, DDC7 displayed the best performance with an eta value 6.53% under 4 mu m thick scattering layer (condition 1+1), which was boosted to 7.49% under 8 mu m thick scattering layer (condition 1+2). The photo-stability measurements indicated that all the three dyes are fairly photo-stable.
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| 2. |
- Liu, Anbu, et al.
(författare)
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DDR1/2 enhance KIT activation and imatinib resistance of primary and secondary KIT mutants in gastrointestinal stromal tumors
- 2024
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Ingår i: Molecular Carcinogenesis. - 0899-1987. ; 63:1, s. 75-93
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Tidskriftsartikel (refereegranskat)abstract
- Gastrointestinal stromal tumors (GISTs) are predominantly initiated by KIT mutations. In this study, we observed that discoidin domain receptors 1 and 2 (DDR1 and DDR2) exhibited high expression in GISTs, were associated with KIT, and enhanced the activation of both wild-type KIT and primary KIT mutants. Inhibition of DDR1/2 led to a reduction in the activation of KIT and its downstream signaling molecules, ultimately impairing GIST cell survival and proliferation in vitro. Consequently, treatment of mice carrying germline KIT/V558A mutation with DDR1/2 inhibitor significantly impeded tumor growth, and the combined use of DDR1/2 inhibitor and imatinib, the first-line targeted therapeutic agent for GISTs, markedly enhanced tumor growth suppression. In addition, DDR1/2 inhibition resulted in decreased KIT expression, while KIT inhibition led to upregulation of DDR1/2 expression in GISTs. The presence of DDR1/2 also decreased the sensitivity of wild-type KIT or primary KIT mutants to imatinib, indicating a possible role for DDR1/2 in promoting GIST survival during KIT-targeted therapy. The development of drug-resistant secondary KIT mutations is a primary factor contributing to GIST recurrence following targeted therapy. Similar to primary KIT mutants, DDR1/2 can associate with and enhance the activation of secondary KIT mutants, further diminishing their sensitivity to imatinib. In summary, our data demonstrate that DDR1/2 contribute to KIT activation in GISTs and strengthen resistance to imatinib for both primary and secondary KIT mutants, providing a rationale for further exploration of DDR1/2 targeting in GIST treatment.
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| 3. |
- Tian, Guojian, et al.
(författare)
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A new D-A-pi-A type organic sensitizer based on substituted dihydroindolo [2,3-b] carbazole and DPP unit with a bulky branched alkyl chain for highly efficient DSCs
- 2015
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Ingår i: Journal of Materials Chemistry A. - : Royal Society of Chemistry (RSC). - 2050-7488 .- 2050-7496. ; 3:7, s. 3777-3784
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Tidskriftsartikel (refereegranskat)abstract
- Two new D-A-pi-A configuration metal-free organic sensitizers (T1-T2) based on 5,7-dihexyl-6,12-diphenyl-5,7-dihydroindolo[2,3-b]carbazole and a DPP unit with a bulky branched alkyl chain have been synthesized for dye-sensitized solar cells. Due to a bulky branched alkyl chain being attached to the donor and DPP unit, both compounds obtain high V-oc values. Under standard global AM 1.5 solar light conditions, the T1 based-device gives a high conversion efficiency of 8.24% with a J(sc) of 15.72 mA cm(-2), a V-oc of 0.74 V and a FF of 0.71. These excellent performances make the donor dihydroindolo[2,3-b] carbazole and DPP unit promising candidates for further application in DSCs.
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| 4. |
- Wu, Panpan, et al.
(författare)
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Highly efficient fluorene/indole-based hole transport materials for green PhOLEDs
- 2019
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Ingår i: Dyes and Pigments. - : Elsevier BV. - 0143-7208 .- 1873-3743. ; 162, s. 153-159
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Tidskriftsartikel (refereegranskat)abstract
- Three hole transport materials, FIPN-p-PCz, FIPN-p-TPA and FIPN-DPCz, incorporating fluorene/indole core with carbazole or triphenylamine unit were synthesized and fully characterized. The photophysical properties, thermal properties and electrochemical properties of these three compounds were fully investigated. The FIPN-based hole transport materials show high thermal stability(Td > 420 °C) and appropriate highest occupied molecular orbital (HOMO) level (∼-5.2 eV). Green phosphorescent organic light-emitting diodes (PhOLEDs) using these FIPN-based derivatives were fabricated to investigate the device performance, compared with NPB as the reference hole transport material. It turned out that the devices using these three compounds exhibited superior performance than that of the NPB-based PhOLED device. Especially, the FIPN-p-PCz based device showed outstanding electroluminescence performance with the maximum current efficiency and external quantum efficiency of 53.7 cd/A and 17.3%, respectively, which was almost twice that of the NPB based device.
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| 5. |
- Zhang, Youwei, et al.
(författare)
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Extending the Spectral Responsivity of MoS2 Phototransistors by Incorporating Up-Conversion Microcrystals
- 2018
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Ingår i: Advanced Optical Materials. - : Wiley. - 2162-7568 .- 2195-1071. ; 6:21
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Tidskriftsartikel (refereegranskat)abstract
- Layered 2D semiconductors are characterized by unique photoelectric properties and, therefore, constitute a new class of basic building block for next‐generation optoelectronics. However, their wide bandgaps limit the spectral responsivity to a narrow range. Here, a facile approach is demonstrated by integrating β‐NaYF4:Yb3+, Er3+ up‐conversion microcrystals (UCMCs) with monolayer‐MoS2 phototransistors to break this bandgap‐imposed barrier and to drastically extend the responsivity range. In essence, the UCMCs up‐convert a near‐infrared excitation at 980 nm to visible light of photons with energy matching the large bandgap (i.e., 1.8 eV) of monolayer‐MoS2, thereby activating the phototransistor with remarkable photocurrent and minimum interference. This approach leads to preservation of the excellent electrical merits of monolayer‐MoS2 and simultaneous retention of its low dark current and high photoresponsivity to the above‐bandgap lights. Significantly, an enhancement by over 1000 times is achieved for both responsivity and specific detectivity at 980 nm excitation. Moreover, the rate of response is kept identical to that when the MoS2 phototransistor is excited by a visible light. Therefore, integrating with UCMCs can enable the emerging 2D semiconductors of wide bandgap to respond to infrared excitations with high efficacy and without sacrificing their performance in the visible region.
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