SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Tijani A) "

Sökning: WFRF:(Tijani A)

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  • Tijani, Muyideen K., et al. (författare)
  • Acquisition, maintenance and adaptation of invasion inhibitory antibodies against Plasmodium falciparum invasion ligands involved in immune evasion
  • 2017
  • Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 12:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Erythrocyte-binding antigens (EBAs) and P. falciparum reticulocyte-binding homologue proteins (PfRhs) are two important protein families that can vary in expression and utilization by P. falciparum to evade inhibitory antibodies. We evaluated antibodies at repeated time-points among individuals living in an endemic region in Nigeria over almost one year against these vaccine candidates. Antibody levels against EBA140, EBA175, EBA181, PfRh2, PfRh4, and MSP2, were measured by ELISA. We also used parasites with disrupted EBA140, EBA175 and EBA181 genes to show that all these were targets of invasion inhibitory antibodies. However, antigenic targets of inhibitory antibodies were not stable and changed substantially over time in most individuals, independent of age. Antibodies levels measured by ELISA also varied within and between individuals over time and the antibodies against EBA181, PfRh2 and MSP2 declined more rapidly in younger individuals (15 years) compared with older (>15). The breadth of high antibody responses over time was more influenced by age than by the frequency of infection. High antibody levels were associated with a more stable invasion inhibitory response, which could indicate that during the long process of formation of immunity, many changes not only in levels but also in functional responses are needed. This is an important finding in understanding natural immunity against malaria, which is essential for making an efficacious vaccine.
  •  
3.
  • Iqbal, Muhammad Imran, et al. (författare)
  • Detection of Vascular Intersection in Retina Fundus Image Using Modified Cross Point Number and Neural Network Technique
  • 2008
  • Konferensbidrag (refereegranskat)abstract
    • Vascular intersection can be used as one of the symptoms for monitoring and diagnosis of diabetic retinopathy from fundus images. In this work we apply the knowledge of digital image processing, fuzzy logic and neural network technique to detect bifurcation and vein-artery cross-over points in fundus images. The acquired images undergo preprocessing stage for illumination equalization and noise removal. Segmentation stage clusters the image into two distinct classes by the use of fuzzy c-means technique, neural network technique and modified cross-point number (MCN) methods were employed for the detection of bifurcation and cross-over points. MCN uses a 5x5 window with 16 neighboring pixels for efficient detection of bifurcation and cross over points in fundus images. Result obtained from applying this hybrid method on both real and simulated vascular points shows that this method perform better than the existing simple cross-point number (SCN) method, thus an improvement to the vascular point detection and a good tool in the monitoring and diagnosis of diabetic retinopathy. ©2008 IEEE.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy