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Sökning: WFRF:(Tindall David)

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1.
  • Kyrpides, Nikos C, et al. (författare)
  • Genomic encyclopedia of bacteria and archaea: sequencing a myriad of type strains.
  • 2014
  • Ingår i: PLoS biology. - : Public Library of Science (PLoS). - 1545-7885. ; 12:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.
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2.
  • Andriole, Gerald L, et al. (författare)
  • Effect of dutasteride on the risk of prostate cancer.
  • 2010
  • Ingår i: The New England journal of medicine. - 1533-4406. ; 362:13, s. 1192-202
  • Tidskriftsartikel (refereegranskat)abstract
    • We conducted a study to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease.
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3.
  • Broadbent, Jeffrey, et al. (författare)
  • Conflicting Climate Change Frames in a Global Field of Media Discourse
  • 2016
  • Ingår i: Socius: Sociological Research for a Dynamic World. - : SAGE Publications. - 2378-0231. ; 1:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Reducing global emissions will require a global cosmopolitan culture built from detailed attention to conflicting national climate change frames (interpretations) in media discourse. The authors analyze the global field of media climate change discourse using 17 diverse cases and 131 frames. They find four main conflicting dimensions of difference: validity of climate science, scale of ecological risk, scale of climate politics, and support for mitigation policy. These dimensions yield four clusters of cases producing a fractured global field. Positive values on the dimensions show modest association with emissions reductions. Data-mining media research is needed to determine trends in this global field.
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  • Resultat 1-3 av 3

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