| 1. |
- Kekäläinen, Tiia, et al.
(författare)
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Does personality moderate the efficacy of physical and cognitive training interventions? A 12-month randomized controlled trial in older adults
- 2023
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Ingår i: Personality and Individual Differences. - : Elsevier. - 0191-8869 .- 1873-3549. ; 202
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Tidskriftsartikel (refereegranskat)abstract
- This study investigated whether personality traits moderate the effects of a 12-month physical or combined physical and cognitive training interventions on physical and cognitive functioning. Participants were community-dwelling 70–85-year-old adults (n = 314). They were randomly assigned to physical training (weekly supervised walking/balance and strength/balance training, home exercises 2–3×/wk and moderate aerobic activity) or to a physical and cognitive training group (the same physical training and computer training on executive functions 3–4×/wk). The outcomes assessed at baseline and post-intervention were physical (maximum gait speed, six-minute walking distance, dual-task cost on gait speed) and cognitive functioning (Stroop, Trail-Making Test-B, verbal fluency, CERAD total score). Personality traits (NEO-PI-3, n = 239) were assessed post-intervention. Personality traits did not moderate intervention effects on physical functioning. Higher openness was associated with greater improvement in CERAD scores, especially in the physical and cognitive training group (group×time×trait B = -0.08, p = .038). Lower neuroticism (time×trait B = -0.04, p = .021) and higher conscientiousness (time×trait B = 0.04, p = .027) were associated with greater improvement in CERAD scores in both groups. Personality traits had mostly null moderating effects across physical and cognitive outcomes, with the possible exception of CERAD score. Individuals with more adaptive personality traits gained more on global cognitive scores during a 12-month training intervention.
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| 2. |
- Savikangas, Tiina, et al.
(författare)
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The effects of a physical and cognitive training intervention vs. physical training alone on older adults' physical activity : A randomized controlled trial with extended follow-up during COVID-19
- 2021
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Ingår i: PLOS ONE. - : Public Library of Science. - 1932-6203. ; 16:10, s. 1-20
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Tidskriftsartikel (refereegranskat)abstract
- Background Executive functions underlie self-regulation and are thus important for physical activity and adaptation to new situations. The aim was to investigate, if yearlong physical and cognitive training (PTCT) had greater effects on physical activity among older adults than physical training (PT) alone, and if executive functions predicted physical activity at baseline, after six (6m) and twelve months (12m) of the interventions, one-year post-intervention follow-up and an extended follow-up during COVID-19 lockdown. Methods Data from a single-blinded, parallel-group randomized controlled trial (PASSWORD-study, ISRCTN52388040) were utilized. Participants were 70-85 years old community-dwelling men and women from Jyvaskyla, Finland. PT (n = 159) included supervised resistance, walking and balance training, home-exercises and self-administered moderate activity. PTCT (n = 155) included PT and cognitive training targeting executive functions on a computer program. Physical activity was assessed with a one-item, seven-scale question. Executive functions were assessed with color-word Stroop, Trail Making Test (TMT) B-A and Letter Fluency. Changes in physical activity were modeled with multinomial logistic models and the impact of executive functions on physical activity with latent change score models. Results No significant group-by-time interaction was observed for physical activity (p>0.1). The subjects were likely to select an activity category higher than baseline throughout the study (pooled data: B = 0.720-1.614, p<0.001-0.046). Higher baseline Stroop predicted higher physical activity through all subsequent time-points (pooled data: B = 0.011-0.013, p = 0.015-0.030). Higher baseline TMT B-A predicted higher physical activity at 6m (pooled data: B = 0.007, p = 0.006) and during COVID-19 (B = 0.005, p = 0.030). In the PT group, higher baseline Letter Fluency predicted higher physical activity at 12m (B = -0.028, p = 0.030) and follow-up (B = -0.042, p = 0.002). Conclusions Cognitive training did not have additive effects over physical training alone on physical activity, but multicomponent training and higher executive function at baseline may support adaptation to and maintenance of a physically active lifestyle among older adults.
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| 3. |
- Sipila, Sarianna, et al.
(författare)
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Effects of physical and cognitive training on gait speed and cognition in older adults : A randomized controlled trial
- 2021
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Ingår i: Scandinavian Journal of Medicine and Science in Sports. - : Wiley-Blackwell. - 0905-7188 .- 1600-0838. ; 31:7, s. 1518-1533
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Tidskriftsartikel (refereegranskat)abstract
- Gait speed is a measure of health and functioning. Physical and cognitive determinants of gait are amenable to interventions, but best practices remain unclear. We investigated the effects of a 12-month physical and cognitive training (PTCT) on gait speed, dual-task cost in gait speed, and executive functions (EFs) compared with physical training (PT) (ISRCTN52388040). Community-dwelling older adults, who did not meet physical activity recommendations, were recruited (n = 314). PT included supervised walking/balance (once weekly) and resistance/balance training (once weekly), home exercises (2-3 times weekly), and moderate aerobic activity 150 min/week in bouts of >10 min. PTCT included the PT and computer training (CT) on EFs 15-20 min, 3-4 times weekly. The primary outcome was gait speed. Secondary outcomes were 6-min walking distance, dual-task cost in gait speed, and EF (Stroop and Trail Making B-A). The trial was completed by 93% of the participants (age 74.5 [SD3.8] years; 60% women). Mean adherence to supervised sessions was 59%-72% in PT and 62%-77% in PTCT. Home exercises and CT were performed on average 1.9 times/week. Weekly minutes spent in aerobic activities were 188 (median 169) in PT and 207 (median 180) in PTCT. No significant interactions were observed for gait speed (PTCT-PT, 0.02; 95%CI -0.03, 0.08), walking distance (-3.8; -16.9, 9.3) or dual-task cost (-0.22; -1.74, 1.30). Stroop improvement was greater after PTCT than PT (-6.9; -13.0, -0.8). Complementing physical training with EFs training is not essential for promotion of gait speed. For EF's, complementing physical training with targeted cognitive training provides additional benefit.
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| 4. |
- Sipilä, Sarianna, et al.
(författare)
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Promoting safe walking among older people : the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial
- 2018
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Ingår i: BMC Geriatrics. - : BioMed Central. - 1471-2318 .- 1471-2318. ; 18
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Tidskriftsartikel (refereegranskat)abstract
- Background: Safe and stable walking is a complex process involving the interaction of neuromuscular, sensory and cognitive functions. As physical and cognitive functions deteriorate with ageing, training of both functions may have more beneficial effects on walking and falls prevention than either alone. This article describes the study design, recruitment strategies and interventions of the PASSWORD study investigating whether a combination of physical and cognitive training (PTCT) has greater effects on walking speed, dual-task cost in walking speed, fall incidence and executive functions compared to physical training (PT) alone among 70-85-year-old community-dwelling sedentary or at most moderately physically active men and women.Methods: Community-dwelling sedentary or at most moderately physically active, men and women living in the city of Jyvaskyla will be recruited and randomized into physical training (PT) and physical and cognitive training (PTCT). The 12-month interventions include supervised training sessions and home exercises. Both groups attend physical training intervention, which follows the current physical activity guidelines. The PTCT group performes also a web-based computer program targeting executive functions. Outcomes will be assessed at baseline and at 6 and 12 months thereafter. Falls data are collected during the interventions and the subsequent one-year follow-up. The primary outcome is 10-m walking speed. Secondary outcomes include 6-min walking distance, dual-task cost in walking speed, fall incidence and executive function assessed with color Stroop and Trail Making A and B tests. Explanatory outcomes include e.g. body composition and bone characteristics, physical performance, physical activity, life-space mobility, fall-related self-efficacy, emotional well-being and personality characteristics.Discussion: The study is designed to capture the additive and possible synergistic effects of physical and cognitive training. When completed, the study will provide new knowledge on the effects of physical and cognitive training on the prevention of walking limitations and rate of falls in older people. The expected results will be of value in informing strategies designed to promote safe walking among older people and may have a significant health and socio-economic impact.
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| 5. |
- Tirkkonen, Anna, et al.
(författare)
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Associations Between Physical and Executive Functions Among Community-Dwelling Older Men and Women
- 2022
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Ingår i: Journal of Aging and Physical Activity. - : Human Kinetics. - 1063-8652 .- 1543-267X. ; 30:2, s. 332-339
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Tidskriftsartikel (refereegranskat)abstract
- Walking is a complex task requiring the interplay of neuromuscular, sensory, and cognitive functions. Owing to the age-related decline in cognitive and physical functions, walking may be compromised in older adults, for cognitive functions, especially poor performance in executive functions, is associated with slow walking speed. Hence, the aim of this study was to investigate the associations between different subdomains of executive functions and physical functions and whether the associations found differ between men and women. Multiple linear regression analysis was performed on data collected from 314 community-dwelling older adults who did not meet physical activity guidelines but had intact cognition. Our results showed that, while executive functions were associated with gait and lower extremity functioning, the associations depended partly on the executive process measured and the nature of the physical task. Moreover, the associations did not differ between the sexes.
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| 6. |
- Tirkkonen, Anna, et al.
(författare)
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Participant characteristics associated with the effects of a physical and cognitive training program on executive functions
- 2022
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Ingår i: Frontiers in Aging Neuroscience. - : Frontiers Media S.A.. - 1663-4365 .- 1663-4365. ; 14
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Tidskriftsartikel (refereegranskat)abstract
- Background: Physical and cognitive interventions have been shown to induce positive effects on older adults’ executive functioning. However, since participants with different background characteristics may respond differently to such interventions, we investigated whether training effects on executive functions were associated with sex, training compliance, and age. We also investigated if change in global cognition was associated with physical and cognitive training intervention-induced changes in executive functions. Methods: Exploratory data from a randomized controlled trial were analyzed. Participants were 70–85-year-old men and women who received a 12-month physical (PT) or physical and cognitive training (PTCT) intervention. Measurements of executive functions related to inhibition (Stroop), set shifting (Trail Making Test B) and updating (Verbal Fluency) were performed at baseline and 12 months. Data were analyzed using a longitudinal linear path model for the two measurements occasion. Results: Stroop improved significantly more in women and participants in the low compliance subgroup who received PTCT than in counterparts in the PT subgroup (difference –8.758, p = 0.001 and difference –8.405, p = 0.010, respectively). In addition, TMT B improved after the intervention in the low compliance PTCT subgroup and worsened in the corresponding PT subgroup (difference –15.034, p = 0.032). No other significant associations were observed. Conclusion: Executive functions in women and in the participants, who only occasionally engaged in training showed greater improvement after the PTCT than PT intervention. However, the additional extra benefit gained from the PTCT intervention was uniquely expressed in each executive function measured in this study.
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| 7. |
- Tirkkonen, Anna, et al.
(författare)
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S15-5 Executive and physical functions among community-dwelling older adults : results from the PASSWORD study
- 2023
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Ingår i: European Journal of Public Health. - : Oxford University Press. - 1101-1262 .- 1464-360X. ; 33:Supplement_1, s. I30-I31
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- PurposeCognitive and physical functions are key factors for safe walking. As these functions deteriorate with age walking may be compromised among older adults. However, cognitive and physical decline may be attenuated with cognitive and physical training. This study investigated the associations between cognitive, especially executive, and physical functions and sex differences in these associations in physically inactive older adults. Additionally, the role of participant characteristics in cognitive and physical training-induced change in executive functions was investigated.Methods314 older adults aged 70-85 were recruited and randomized to PTCT (N = 155) or PT (N = 159). PT included two supervised training sessions a week and home exercises. PTCT included PT and cognitive training. Measurements were organized at baseline, 6 and 12 months. Physical functions were assessed with 10-meter maximal walking speed, 6-minutes walking distance, dual-task cost in walking speed, habitual walking speed and Short Physical Performance Battery (SPPB). Core skills of executive functions were assessed with Stroop (inhibition), Trail Making Test B (set shifting) and Letter Verbal Fluency (updating). Training compliance was based on participation in supervised training sessions. The data was analyzed with multiple linear regression analyses and longitudinal two-group linear path models.ResultsMean age of the participants was 74.5. Results showed that Verbal Fluency test was positively associated with faster maximal and habitual walking speed (β = 0.272, p<0.001, β = 0.184, p = 0.009 respectively), longer 6-min walking distance (β = 0.242, p<0.001) and higher scores in SPPB (β = 0.234, p<0.001), additionally, TMT B-A was positively associated with higher scores in SPPB (β=-0.236, p<0.001). No significant sex-differences were found. Additionally, Stroop improved significantly more in women and participants in the low compliance subgroup who received PTCT compared to participant receiving PT (difference -8.758, p = 0.001 and difference in -8.405, p = 0.010 respectively) No other significant associations were observed.ConclusionExecutive and physical functions are positively associated in older adults. The association depends on the physical task and the executive subdomain. Physical and cognitive training improves older adults’ executive functions. Women and participants who only occasionally engaged in training may gain additional benefits for inhibition from physical and cognitive training compared to physical training.
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| 8. |
- Tirkkonen, Anna, et al.
(författare)
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S15-5 Executive and physical functions among community-dwelling older adults : results from the PASSWORD study
- 2023
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Ingår i: European Journal of Public Health. - : Oxford University Press. - 1101-1262 .- 1464-360X. ; 33:Supplement_1
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: Cognitive and physical functions are key factors for safe walking. As these functions deteriorate with age walking may be compromised among older adults. However, cognitive and physical decline may be attenuated with cognitive and physical training. This study investigated the associations between cognitive, especially executive, and physical functions and sex differences in these associations in physically inactive older adults. Additionally, the role of participant characteristics in cognitive and physical training-induced change in executive functions was investigatedMethods: 314 older adults aged 70-85 were recruited and randomized to PTCT (N = 155) or PT (N = 159). PT included two supervised training sessions a week and home exercises. PTCT included PT and cognitive training. Measurements were organized at baseline, 6 and 12 months. Physical functions were assessed with 10-meter maximal walking speed, 6-minutes walking distance, dual-task cost in walking speed, habitual walking speed and Short Physical Performance Battery (SPPB). Core skills of executive functions were assessed with Stroop (inhibition), Trail Making Test B (set shifting) and Letter Verbal Fluency (updating). Training compliance was based on participation in supervised training sessions. The data was analyzed with multiple linear regression analyses and longitudinal two-group linear path models.Results: Mean age of the participants was 74.5. Results showed that Verbal Fluency test was positively associated with faster maximal and habitual walking speed (β = 0.272, p<0.001, β = 0.184, p = 0.009 respectively), longer 6-min walking distance (β = 0.242, p<0.001) and higher scores in SPPB (β = 0.234, p<0.001), additionally, TMT B-A was positively associated with higher scores in SPPB (β=-0.236, p<0.001). No significant sex-differences were found. Additionally, Stroop improved significantly more in women and participants in the low compliance subgroup who received PTCT compared to participant receiving PT (difference -8.758, p = 0.001 and difference in -8.405, p = 0.010 respectively) No other significant associations were observed.Conclusion: Executive and physical functions are positively associated in older adults. The association depends on the physical task and the executive subdomain. Physical and cognitive training improves older adults’ executive functions. Women and participants who only occasionally engaged in training may gain additional benefits for inhibition from physical and cognitive training compared to physical training.
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| 9. |
- Turunen, Katri M., et al.
(författare)
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Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults : Results From a Randomized Controlled Trial
- 2021
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Ingår i: The journals of gerontology. Series A, Biological sciences and medical sciences. - : Oxford University Press. - 1079-5006 .- 1758-535X. ; 77:7, s. 1430-1437
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Tidskriftsartikel (refereegranskat)abstract
- Background The aim of this study is to investigate whether combined cognitive and physical training provides additional benefits to fall prevention when compared with physical training (PT) alone in older adults. Methods This is a prespecified secondary analysis of a single-blind, randomized controlled trial involving community-dwelling men and women aged 70-85 years who did not meet the physical activity guidelines. The participants were randomized into combined physical and cognitive training (PTCT, n = 155) and PT (n = 159) groups. PT included supervised and home-based physical exercises following the physical activity recommendations. PTCT included PT and computer-based cognitive training. The outcome was the rate of falls over the 12-month intervention (PTCT, n = 151 and PT, n = 155) and 12-month postintervention follow-up (PTCT, n = 143 and PT, n = 148). Falls were ascertained from monthly diaries. Exploratory outcomes included the rate of injurious falls, faller/recurrent faller/fall-related fracture status, and concern about falling. Results Estimated incidence rates of falls per person-year were 0.8 (95% confidence interval [CI] 0.7-1.1) in the PTCT and 1.1 (95% CI 0.9-1.3) in the PT during the intervention and 0.8 (95% CI 0.7-1.0) versus 1.0 (95% CI 0.8-1.1), respectively, during the postintervention follow-up. There was no significant difference in the rate of falls during the intervention (incidence rate ratio [IRR] = 0.78; 95% CI 0.56-1.10, p = .152) or in the follow-up (IRR = 0.83; 95% CI 0.59-1.15, p = .263). No significant between-group differences were observed in any exploratory outcomes. Conclusion A yearlong PTCT intervention did not result in a significantly lower rate of falls or concern about falling than PT alone in older community-dwelling adults.
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