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- El-Seedi, Hesharn Rushdey, et al.
(författare)
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Constituents of Hypericum laricifolium and Their Cyclooxygenase (COX)Enzyme Activities
- 2003
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Ingår i: Chemical and pharmaceutical bulletin. - : Pharmaceutical Society of Japan. - 0009-2363 .- 1347-5223. ; 51:12, s. 1439-1440
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Tidskriftsartikel (refereegranskat)abstract
- Investigation of the aerial parts of the medicinal plant Hypericum laricifolium led to the isolation of two new natural products, hentriacontanyl caffeate (1a), nonacosanyl caffeate (1b). In addition, stigmasterol, beta-sitosterol, 3-epi-betulinic acid (2), caffeic acid (3), ferulic acid, docosanol, p-hydroxybenzoic acid, 3,4-dimethoxy benzoic acid, quercetin (4), quercetin-3-O-galactoside (5), quercetin-3-O-rutinoside (6), quercetin-3-O-rhamnoside (7), quercetin-3-O-glucuronide (8) and shikimic acid were also isolated. The structures were determined by 1D- and 2D-NMR, mass spectrometry, and chemical transformations. The anti-inflammatory effects of the isolated compounds were discussed briefly.
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