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| 2. |
- Ashcroft, Michael, et al.
(författare)
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Multilayer Analysis of Online Illicit Marketplaces
- 2016
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Ingår i: 2016 European Intelligence And Security Informatics Conference (EISIC). - : IEEE. - 9781509028573 ; , s. 199-199
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Konferensbidrag (refereegranskat)
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| 3. |
- Beal, Jacob, et al.
(författare)
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Robust estimation of bacterial cell count from optical density
- 2020
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Ingår i: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
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Tidskriftsartikel (refereegranskat)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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| 4. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 5. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 6. |
- Danaei, Goodarz, et al.
(författare)
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Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants
- 2015
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Ingår i: The Lancet Diabetes & Endocrinology. - 2213-8595 .- 2213-8587. ; 3:8, s. 624-637
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Tidskriftsartikel (refereegranskat)abstract
- Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in different regions. Methods We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defining diabetes. Diabetes was defined using HbA(1c) (HbA(1c) >= 6 . 5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT definitions (FPG >= 7 . 0 mmol/L or 2hOGTT >= 11 . 1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using different definitions graphically and by regression analyses. We calculated sensitivity and specificity of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specificity in each survey, and then pooled results using a random-effects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori. Findings Population prevalence of diabetes based on FPG- or-2hOGTT was correlated with prevalence based on FPG alone (r= 0 . 98), but was higher by 2-6 percentage points at different prevalence levels. Prevalence based on HbA(1c) was lower than prevalence based on FPG in 42 . 8% of age-sex-survey groups and higher in another 41 . 6%; in the other 15 . 6%, the two definitions provided similar prevalence estimates. The variation across studies in the relation between glucose-based and HbA(1c)-based prevalences was partly related to participants' age, followed by natural logarithm of per person gross domestic product, the year of survey, mean BMI, and whether the survey population was national, subnational, or from specific communities. Diabetes defined as HbA(1c) 6 . 5% or more had a pooled sensitivity of 52 . 8% (95% CI 51 . 3-54 . 3%) and a pooled specificity of 99 . 74% (99 . 71-99 . 78%) compared with FPG 7 . 0 mmol/L or more for diagnosing previously undiagnosed participants; sensitivity compared with diabetes defined based on FPG-or-2hOGTT was 30 . 5% (28 . 7-32 . 3%). None of the preselected study-level characteristics explained the heterogeneity in the sensitivity of HbA(1c) versus FPG. Interpretation Different biomarkers and definitions for diabetes can provide different estimates of population prevalence of diabetes, and differentially identify people without previous diagnosis as having diabetes. Using an HbA(1c)-based definition alone in health surveys will not identify a substantial proportion of previously undiagnosed people who would be considered as having diabetes using a glucose-based test.
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| 7. |
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| 8. |
- Galluccio, Carla, et al.
(författare)
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Robustness and Sensitivity of Network-Based Topic Detection
- 2023
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Ingår i: Complex Networks and their Applications XI. - Cham : Springer. - 9783031211331 - 9783031211317 - 9783031211300 ; , s. 259-270
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Konferensbidrag (refereegranskat)abstract
- In the context of textual analysis, network-based procedures for topic detection are gaining attention as an alternative to classical topic models. Network-based procedures are based on the idea that documents can be represented asword cooccurrence networks, where topics are defined as groups of strongly connected-words. Although many works have used network-based procedures for topic detection, there is a lack of systematic analysis of how different design choices, such as the building of the word co-occurrence matrix and the selection of the community detection algorithm, affect the final results in terms of detected topics. In this work, we present the results obtained by analysing a widely used corpus of news articles, showing how and to what extent the choices made during the design phase affect the results.
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| 9. |
- Hanteer, Obaida, et al.
(författare)
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From Interaction to Participation : The Role of the Imagined Audience in Social Media Community Detection and an Application to Political Communication on Twitter
- 2018
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Ingår i: 2018 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM). - : IEEE Computer Society. - 9781538660515 ; , s. 531-534
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Konferensbidrag (refereegranskat)abstract
- In the context of community detection in online social media, a lot of effort has been put into the definition of sophisticated network clustering algorithms and much less on the equally crucial process of obtaining high-quality input data. User-interaction data explicitly provided by social media platforms has largely been used as the main source of data because of its easy accessibility. However, this data does not capture a fundamental and much more frequent type of participatory behavior where users do not explicitly mention others but direct their messages to an invisible audience following a common hashtag. In the context of multiplex community detection, we show how to construct an additional data layer about user participation not relying on explicit interactions between users, and how this layer can be used to find different types of communities in the context of Twitter political communication.
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| 10. |
- Interdonato, Roberto, et al.
(författare)
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Multilayer network simplification : Approaches, models and methods
- 2020
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Ingår i: Computer Science Review. - : Elsevier BV. - 1574-0137 .- 1876-7745. ; 36
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Forskningsöversikt (refereegranskat)abstract
- Multilayer networks have been widely used to represent and analyze systems of interconnected entities where both the entities and their connections can be of different types. However, real multilayer networks can be difficult to analyze because of irrelevant information, such as layers not related to the objective of the analysis, because of their size, or because traditional methods defined to analyze simple networks do not have a straightforward extension able to handle multiple layers. Therefore, a number of methods have been devised in the literature to simplify multilayer networks with the objective of improving our ability to analyze them. In this article we provide a unified and practical taxonomy of existing simplification approaches, and we identify categories of multilayer network simplification methods that are still underdeveloped, as well as emerging trends.
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