| 1. |
- Bailey, S. C. C., et al.
(författare)
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Obtaining accurate mean velocity measurements in high Reynolds number turbulent boundary layers using Pitot tubes
- 2013
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Ingår i: Journal of Fluid Mechanics. - : Cambridge University Press (CUP). - 0022-1120 .- 1469-7645. ; 715, s. 642-670
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Tidskriftsartikel (refereegranskat)abstract
- This article reports on one component of a larger study on measurement of the zero-pressure-gradient turbulent flat plate boundary layer, in which a detailed investigation was conducted of the suite of corrections required for mean velocity measurements performed using Pitot tubes. In particular, the corrections for velocity shear across the tube and for blockage effects which occur when the tube is in close proximity to the wall were investigated using measurements from Pitot tubes of five different diameters, in two different facilities, and at five different Reynolds numbers ranging from Reθ = 11 100 to 67 000. Only small differences were found amongst commonly used corrections for velocity shear, but improvements were found for existing near-wall proximity corrections. Corrections for the nonlinear averaging of the velocity fluctuations were also investigated, and the results compared to hot-wire data taken as part of the same measurement campaign. The streamwise turbulence-intensity correction was found to be of comparable magnitude to that of the shear correction, and found to bring the hot-wire and Pitot results into closer agreement when applied to the data, along with the other corrections discussed and refined here.
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| 2. |
- Edwards, Robert A., et al.
(författare)
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Global phylogeography and ancient evolution of the widespread human gut virus crAssphage
- 2019
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Ingår i: Nature Microbiology. - : Springer Science and Business Media LLC. - 2058-5276. ; 4:10, s. 1727-1736
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Tidskriftsartikel (refereegranskat)abstract
- Microbiomes are vast communities of microorganisms and viruses that populate all natural ecosystems. Viruses have been considered to be the most variable component of microbiomes, as supported by virome surveys and examples of high genomic mosaicism. However, recent evidence suggests that the human gut virome is remarkably stable compared with that of other environments. Here, we investigate the origin, evolution and epidemiology of crAssphage, a widespread human gut virus. Through a global collaboration, we obtained DNA sequences of crAssphage from more than one-third of the world's countries and showed that the phylogeography of crAssphage is locally clustered within countries, cities and individuals. We also found fully colinear crAssphage-like genomes in both Old-World and New-World primates, suggesting that the association of crAssphage with primates may be millions of years old. Finally, by exploiting a large cohort of more than 1,000 individuals, we tested whether crAssphage is associated with bacterial taxonomic groups of the gut microbiome, diverse human health parameters and a wide range of dietary factors. We identified strong correlations with different clades of bacteria that are related to Bacteroidetes and weak associations with several diet categories, but no significant association with health or disease. We conclude that crAssphage is a benign cosmopolitan virus that may have coevolved with the human lineage and is an integral part of the normal human gut virome.
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| 3. |
- McPherson, Guy R., et al.
(författare)
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The commonly overlooked environmental tipping points
- 2023
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Ingår i: Results in Engineering (RINENG). - : Elsevier BV. - 2590-1230. ; 18, s. 101118-
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Tidskriftsartikel (refereegranskat)abstract
- Climate models are developed based on well-established physical principles applied to past and recent climate changes. There is considerable confidence that the models can also provide estimates of some climate variables (i.e., surface temperature, CO2 levels, ocean heat content). Despite advanced mathematical developments in the field of climate modeling, the existing climate models suffer from the following major limitations: first, the models do not consider that their estimations will be highly unreliable when a tipping point is triggered; secondly, many of the environmental tipping points are already triggered, however their existence is overlooked; and third, the existing climate models do not consider the interrelations among the tipping points (i.e., one tipping point can trigger other tipping points to be tipped more rapidly). Our objective is to describe the importance of environmental "tipping points," the importance of which is often ignored or downplayed in relevant literature. Our analysis, based on extensive multidisciplinary literature searches, reveals that there are many environmental tipping points which are overlooked in climate-modeling studies. We argue that climate modeling could be improved when the tipping points and their interrelations are all considered within the modeling process. We further discuss two other important issues regarding environmental tipping points: first, all tipping points might not be as impactful on the climate system, therefore their relative impacts should be ranked; second, it is in principle impossible to know the exact number of environmental tipping points, therefore even though it could be possible to devise improvements to the existing climate models with our suggestions, it may be impossible to achieve a perfect model to estimate the climate variables of the upcoming years. The remainder of this paper is structured as follows: In the background section, we introduce research on tipping points within commonly used climate models. We explain the aerosol masking effect and ocean dynamics with respect to their commonly overlooked roles as important contributors to environmental change. We introduce remote sensing and AI methods that serve as promising approaches for identification of currently unknown tipping points. We mention perturbation theory, a standard set of mathematical methods in physics that serves as a potentially systematic method to rank environmental tipping points according to their impact on extant climate models. In the discussion section, we make suggestions regarding further research on identifying the typically overlooked tipping points, and we make suggestions to improve climate models by considering additional information presented in the current paper. Finally, we conclude this article summarizing our chief methodological recommendations.
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| 4. |
- Chin, R. C., et al.
(författare)
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Backflow events under the effect of secondary flow of Prandtl's first kind
- 2020
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Ingår i: Physical Review Fluids. - : American Physical Society. - 2469-990X. ; 5:7
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Tidskriftsartikel (refereegranskat)abstract
- A study of the backflow events in the flow through a toroidal pipe at friction Reynolds number Re-tau approximate to 650 is performed and compared with the results in a straight turbulent pipe flow at Re-tau approximate to 500. The statistics and topological properties of the backflow events are analysed and discussed. Conditionally averaged flow fields in the vicinity of the backflow event are obtained, and the results for the torus show a similar streamwise wall-shear stress topology which varies considerably for the azimuthal wall-shear stress when compared to the pipe flow. In the region around the backflow events, critical points are observed. The comparison between the toroidal pipe and its straight counterpart also shows fewer backflow events and critical points in the torus. This is attributed to the secondary flow of Prandtl's first kind present in the toroidal pipe, which is responsible for the convection of momentum from the inner to the outer bend through the core of the pipe, and back from outer bend to the inner bend along the azimuthal direction. These results indicate that backflow events and critical points are genuine features of wall-bounded turbulence, and are not artefacts of specific boundary or inflow conditions in simulations and/or measurement uncertainties in experiments.
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| 5. |
- Honore, Antoine, et al.
(författare)
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An LSTM-based Recurrent Neural Network for Neonatal Sepsis Detection in Preterm Infants
- 2022
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Ingår i: 2022 IEEE Signal Processing in Medicine and Biology Symposium, SPMB 2022. - : Institute of Electrical and Electronics Engineers (IEEE).
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Konferensbidrag (refereegranskat)abstract
- Early and accurate neonatal sepsis detection (NSD) can help reduce mortality, morbidity and antibiotic consumption in premature infants. NSD models are often designed and evaluated in case control setups and using data derived from patient electrocardiogram (ECG) only. In this article, we evaluate our models in a more realistic retrospective cohort study setup. We use data from different modalities, including ECG, chest impedance, pulse oximetry, demographics factors and repetitive measurements of body weights. We study both the vanilla and long-short-term-memory (LSTM) Recurrent Neural Networks (RNN) architectures in a sequence to sequence mapping framework for NSD. We compare the performances of the models with logistic regression (LR) on a variety of classification metrics in a leave-one-out cross validation framework. The population we used contains 118 very low birth weight infants, among which 10 experienced sepsis. We showed that LSTM-based RNNs are both (1) more conservative and (2) more precise than LR or vanilla RNN, with a true negative rate at least +26% higher and a precision score of 0.16 compared to 0.06 for LR. This indicates that LSTM-based RNNs have the potential to reduce the false alarm rate of existing linear models, while providing a reliable diagnostic aid for neonatal sepsis.
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| 6. |
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| 7. |
- Martin, J. A., et al.
(författare)
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Direct numerical simulations of a novel device to fight airborne virus transmission
- 2024
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Ingår i: Physics of fluids. - : AIP Publishing. - 1070-6631 .- 1089-7666. ; 36:2
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Tidskriftsartikel (refereegranskat)abstract
- The SARS-CoV-2 (COVID-19) pandemic has highlighted the crucial role of preventive measures in avoiding the spread of disease and understanding the transmission of airborne viruses in indoor spaces. This study focuses on a novel personal protective equipment consisting of a fan-peaked cap that creates a jet flow of air in front of the individual's face to reduce the concentration of airborne viruses and decrease the risk of infection transmission. Direct numerical simulation is used to analyze the effectiveness of the device under certain conditions, such as the velocity of the airflow, flow orientation, ambient conditions, and geometrical factors.
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| 8. |
- McPherson, Guy R., et al.
(författare)
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Environmental thresholds for mass-extinction events
- 2022
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Ingår i: Results in Engineering (RINENG). - : Elsevier BV. - 2590-1230. ; 13
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Tidskriftsartikel (refereegranskat)abstract
- While the global-average temperatures are rapidly rising, more researchers have been shifting their focus towards the past mass-extinction events in order to show the relations between temperature increase and temperature thresholds which might trigger extinction of species. These temperature and mass-extinction relation graphs are found practical by conservationists and policy makers to determine temperature threshold values to set climate targets. Unfortunately, this approach might be dangerous, because mass-extinction events (MEEs) are related to many environmental parameters and temperature is only one of them. Herein we provide a more comprehensive evaluation of the environmental thresholds required to sustain a habitable planet. Besides, we suggest actions within the sustainable-development goals (SDGs) to observe those critical environmental parameters, in order to assure having an inhabitable planet for the current living species.
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| 9. |
- Rezaeiravesh, Saleh, et al.
(författare)
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An uncertainty-quantification framework for assessing accuracy, sensitivity, and robustness in computational fluid dynamics
- 2022
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Ingår i: Journal of Computational Science. - : Elsevier BV. - 1877-7503 .- 1877-7511. ; 62
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Tidskriftsartikel (refereegranskat)abstract
- Combining different existing uncertainty quantification (UQ) techniques, a framework is obtained to assess a set of metrics in computational physics problems, in general, and computational fluid dynamics (CFD), in particular. The metrics include accuracy, sensitivity and robustness of the simulator's outputs with respect to uncertain inputs and parameters. These inputs and parameters are divided into two groups: based on the variation of the first group (e.g. numerical/computational parameters such as grid resolution), a computer experiment is designed, the data of which may become uncertain due to the parameters of the second group (e.g. finite time-averaging). To construct a surrogate model based on uncertain data, Gaussian process regression (GPR) with observation-dependent (heteroscedastic) noise is used. To estimate the propagated uncertainties in the simulator's outputs from the first group of parameters, a probabilistic version of the polynomial chaos expansion (PCE) is employed Global sensitivity analysis is performed using probabilistic Sobol indices. To illustrate its capabilities, the framework is applied to the scale-resolving simulations of turbulent channel and lid-driven cavity flows using the open-source CFD solver Nek5000. It is shown that at wall distances where the time-averaging uncertainty is high, the quantities of interest are also more sensitive to numerical/computational parameters. In particular for high-fidelity codes such as Nek5000, a thorough assessment of the results' accuracy and reliability is crucial. The detailed analyses and the resulting conclusions can enhance our insight into the influence of different factors on physics simulations, in particular the simulations of high-Reynolds-number turbulent flows including wall turbulence.
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| 10. |
- Ryzhenkov, V., et al.
(författare)
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Simulation of heat and mass transfer in turbulent channel flow using the spectral-element method : Effect of spatial resolution
- 2016
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Ingår i: Journal of Physics, Conference Series. - : Institute of Physics (IOP). - 1742-6588 .- 1742-6596. ; 754:6
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Tidskriftsartikel (refereegranskat)abstract
- We use the open-source code nek5000 to assess the accuracy of high-order spectral element large-eddy simulations (LES) of a turbulent channel flow depending on the spatial resolution compared to the direct numerical simulation (DNS). The Reynolds number Re = 6800 is considered based on the bulk velocity and half-width of the channel. The filtered governing equations are closed with the dynamic Smagorinsky model for subgrid stresses and heat flux. The results show very good agreement between LES and DNS for time-averaged velocity and temperature profiles and their fluctuations. Even the coarse LES grid which contains around 30 times less points than the DNS one provided predictions of the friction velocity within 2.0% accuracy interval.
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