| 1. |
- Beecham, Ashley H, et al.
(författare)
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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
- 2013
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Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:11, s. 1353-60
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Tidskriftsartikel (refereegranskat)abstract
- Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4)). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 subjects with multiple sclerosis and 26,703 healthy controls. In these 80,094 individuals of European ancestry, we identified 48 new susceptibility variants (P < 5.0 × 10(-8)), 3 of which we found after conditioning on previously identified variants. Thus, there are now 110 established multiple sclerosis risk variants at 103 discrete loci outside of the major histocompatibility complex. With high-resolution Bayesian fine mapping, we identified five regions where one variant accounted for more than 50% of the posterior probability of association. This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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| 2. |
- Alexiou, Evangelos, et al.
(författare)
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Subjective and Objective Quality Assessment for Volumetric Video
- 2023. - 1
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Ingår i: Immersive Video Technologies. - Cambridge, Massachusetts, USA : Academic Press. - 9780323917551 - 9780323986236 ; , s. 501-552
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Bokkapitel (refereegranskat)abstract
- Volumetric video (VV) is a novel form of video that allows recreation of real-world scenes in 3D with users consuming the content from any viewpoint they desire. This makes VV best suited for augmented reality (AR) or virtual reality (VR) applications. This freedom necessitates increased user interaction with the VV itself, which brings new challenges to its visual quality assessment. In this chapter, various aspects of VV quality assessment using subjective user studies and objective quality estimation methods are discussed. These aspects include the way or representing 3D models, mode of interaction, display settings (e.g., whether AR or VR headsets are used), rendering parameters, and how the characteristics of point clouds or meshes are used in quality estimation. The chapter discusses the advantages and disadvantages of different methods and provides take away messages for researchers.
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| 3. |
- Grassini, Simone, et al.
(författare)
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Processing of natural scenery is associated with lower attentional and cognitive load compared with urban ones
- 2019
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Ingår i: Journal of Environmental Psychology. - : Academic Press. - 0272-4944 .- 1522-9610. ; 62, s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- Environmental psychology has provided evidence for psychologically favorable effects of exposure to natural settings, by means of controlled laboratory experiments as well as outdoor field studies. Most of these studies have employed subjective rating scales to assess processes and outcomes of exposure to nature, while only few of them have used physiological measures to assess the neural correlates of these benefits. The present study used electroencephalography (EEG) to explore how the brain engages in processing of images of natural vs. urban scenery. During EEG recording, the participants (n = 32) were presented with a series of photos depicting urban or natural scenery. Participants rated the sceneries for their subjective relaxing value. Images of natural scenery were rated as more relaxing compared to the images of urban scenery. Event related potentials suggested a lower attentional demand for images of natural scenery compared to urban ones. Signal spectral analyses revealed differences in brain activity level and cognitive demand between natural and urban scenery. Our data suggest that the visual perception of natural environments calls for less attentional and cognitive processing, compared with urban ones. © 2019 Elsevier Ltd
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| 4. |
- Gutierrez, Jesus, et al.
(författare)
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Subjective evaluation of visual quality and simulator sickness of short 360 videos : ITU-T Rec. P.919
- 2022
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Ingår i: IEEE transactions on multimedia. - 1520-9210 .- 1941-0077. ; 24, s. 3087-3100
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Tidskriftsartikel (refereegranskat)abstract
- Recently an impressive development in immersive technologies, such as Augmented Reality (AR), Virtual Reality (VR) and 360 video, has been witnessed. However, methods for quality assessment have not been keeping up. This paper studies quality assessment of 360 video from the cross-lab tests (involving ten laboratories and more than 300 participants) carried out by the Immersive Media Group (IMG) of the Video Quality Experts Group (VQEG). These tests were addressed to assess and validate subjective evaluation methodologies for 360 video. Audiovisual quality, simulator sickness symptoms, and exploration behavior were evaluated with short (from 10 seconds to 30 seconds) 360 sequences. The following factors' influences were also analyzed: assessment methodology, sequence duration, Head-Mounted Display (HMD) device, uniform and non-uniform coding degradations, and simulator sickness assessment methods. The obtained results have demonstrated the validity of Absolute Category Rating (ACR) and Degradation Category Rating (DCR) for subjective tests with 360 videos, the possibility of using 10-second videos (with or without audio) when addressing quality evaluation of coding artifacts, as well as any commercial HMD (satisfying minimum requirements). Also, more efficient methods than the long Simulator Sickness Questionnaire (SSQ) have been proposed to evaluate related symptoms with 360 videos. These results have been instrumental for the development of the ITU-T Recommendation P.919. Finally, the annotated dataset from the tests is made publicly available for the research community.
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| 5. |
- Gutierrez, Jesus, et al.
(författare)
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Subjective evaluation of visual quality and simulator sickness of short 360 videos : ITU-T Rec. P.919
- 2022
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Ingår i: IEEE transactions on multimedia. - : Institute of Electrical and Electronics Engineers (IEEE). - 1520-9210 .- 1941-0077. ; 24, s. 3087-3100
-
Tidskriftsartikel (refereegranskat)abstract
- Recently an impressive development in immersive technologies, such as Augmented Reality (AR), Virtual Reality (VR) and 360 video, has been witnessed. However, methods for quality assessment have not been keeping up. This paper studies quality assessment of 360 video from the cross-lab tests (involving ten laboratories and more than 300 participants) carried out by the Immersive Media Group (IMG) of the Video Quality Experts Group (VQEG). These tests were addressed to assess and validate subjective evaluation methodologies for 360 video. Audiovisual quality, simulator sickness symptoms, and exploration behavior were evaluated with short (from 10 seconds to 30 seconds) 360 sequences. The following factors' influences were also analyzed: assessment methodology, sequence duration, Head-Mounted Display (HMD) device, uniform and non-uniform coding degradations, and simulator sickness assessment methods. The obtained results have demonstrated the validity of Absolute Category Rating (ACR) and Degradation Category Rating (DCR) for subjective tests with 360 videos, the possibility of using 10-second videos (with or without audio) when addressing quality evaluation of coding artifacts, as well as any commercial HMD (satisfying minimum requirements). Also, more efficient methods than the long Simulator Sickness Questionnaire (SSQ) have been proposed to evaluate related symptoms with 360 videos. These results have been instrumental for the development of the ITU-T Recommendation P.919. Finally, the annotated dataset from the tests is made publicly available for the research communit
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| 6. |
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