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- Tran, Ngoc Hieu, et al.
(författare)
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Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
- 2020
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- The under-representation of several ethnic groups in existing genetic databases and studies have undermined our understanding of the genetic variations and associated traits or diseases in many populations. Cost and technology limitations remain the challenges in performing large-scale genome sequencing projects in many developing countries, including Vietnam. As one of the most rapidly adopted genetic tests, non-invasive prenatal testing (NIPT) data offers an alternative untapped resource for genetic studies. Here we performed a large-scale genomic analysis of 2683 pregnant Vietnamese women using their NIPT data and identified a comprehensive set of 8,054,515 single-nucleotide polymorphisms, among which 8.2% were new to the Vietnamese population. Our study also revealed 24,487 disease-associated genetic variants and their allele frequency distribution, especially 5 pathogenic variants for prevalent genetic disorders in Vietnam. We also observed major discrepancies in the allele frequency distribution of disease-associated genetic variants between the Vietnamese and other populations, thus highlighting a need for genome-wide association studies dedicated to the Vietnamese population. The resulted database of Vietnamese genetic variants, their allele frequency distribution, and their associated diseases presents a valuable resource for future genetic studies.
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| 2. |
- Tolstoy, Daniel, et al.
(författare)
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The indirect effect of online marketing capabilities on the international performance of e-commerce SMEs
- 2021
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Ingår i: International Business Review. - : Elsevier Ltd. - 0969-5931 .- 1873-6149.
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Tidskriftsartikel (refereegranskat)abstract
- International e-commerce is a strong global trend pushed by a tail wind of bolstering economic policies, changing customer behaviors, and improved logistics and technologies. This study investigates the reasons for performance variations among international e-commerce SMEs. Building on the capabilities perspective and market orientation literature, a research model is developed and tested with linear regression and mediation analysis on an effective sample of 99 Swedish SMEs which use e-commerce as an international sales channel. Our study shows that online marketing capabilities are necessary but not sufficient to increase performance among these companies. Our results show that marketing ambidexterity, reflected by both market-driven and market-driving approaches, is instrumental to leverage the effect of online marketing capabilities. © 2021 The Authors
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| 3. |
- Vu, Uyen, et al.
(författare)
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The international ambidexterity of SMEs : An emerging market perspective
- 2021
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Konferensbidrag (refereegranskat)abstract
- In international business research, there is an increasing trend in investigating ambidexterity as a means of understanding how internationalizing firms go about to facilitate the simultaneous pursuit of exploitation and exploration. Even though both theory and empirical data have highlighted the benefits of an ambidextrous approach, a coherent understanding of the resources needed to enable ambidexterity, and a clear picture of how ambidexterity may be achieved in practice is lacking. Recent studies also call for more research to investigate how managerial and organizational capabilities complement each other and affect organizational performance. The objective of this study is to identify specific managerial and organizational capabilities that are important for enabling international ambidexterity in the context of emerging market SMEs. The study aims to contribute to the dynamic capabilities-perspective in an international SME context by disclosing how managerial and organizational capabilities can be used to help SMEs pursue ambidextrous approaches. The study is based on SME-data from an emerging market, Vietnam. Thus, it enriches the scant literature on the pursuit of international ambidexterity in SMEs from Southeast Asian countries.
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