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- Hansson, MR, et al.
(författare)
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BIMODAL ERCP, A NEW WAY OF SEEING THINGS
- 2019
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Ingår i: GASTROINTESTINAL ENDOSCOPY. - : Elsevier BV. - 0016-5107. ; 89:6, s. AB249-AB250
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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- Vinding, MC, et al.
(författare)
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Attenuated beta rebound to proprioceptive afferent feedback in Parkinson's disease
- 2019
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Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1, s. 2604-
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Tidskriftsartikel (refereegranskat)abstract
- Motor symptoms are defining traits in the diagnosis of Parkinson’s disease (PD). A crucial component in motor function is the integration of afferent proprioceptive sensory feedback. Previous studies have indicated abnormal movement-related cortical oscillatory activity in PD, but the role of the proprioceptive afference on abnormal oscillatory activity in PD has not been elucidated. We examine the cortical oscillations in the mu/beta-band (8–30 Hz) in the processing of proprioceptive stimulation in PD patients, ON/OFF levodopa medication, as compared to that of healthy controls (HC). We used a proprioceptive stimulator that generated precisely controlled passive movements of the index finger and measured the induced cortical oscillatory responses following the proprioceptive stimulation using magnetoencephalography. Both PD patients and HC showed a typical beta-band desynchronization during the passive movement. However, the subsequent beta rebound after the passive movement that was almost absent in PD patients compared to HC. Furthermore, we found no difference in the degree of beta rebound attenuation between patients ON and OFF levodopa medication. The results demonstrate a disease-related deterioration in cortical processing of proprioceptive afference in PD.
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| 7. |
- Vujasinovic, Miroslav, et al.
(författare)
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Paraduodenal pancreatitis - problem in the groove
- 2022
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Ingår i: Scandinavian Journal of Gastroenterology. - : TAYLOR & FRANCIS LTD. - 0036-5521 .- 1502-7708.
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Tidskriftsartikel (refereegranskat)abstract
- Background Paraduodenal pancreatitis (PDP) is a particular form of chronic pancreatitis (CP) occurring in and around the duodenal wall. Despite its low prevalence, this rare condition presents a significant challenge in clinical practice. Methods We retrospectively analysed the electronic medical charts of all patients with a diagnosis of chronic pancreatitis and identified those with PDP, between January 1999 and December 2020. Results There were 35 patients diagnosed with PDP (86% males and 14% females); median age of 56 +/- 11 (range 38-80). Alcohol overconsumption was reported in 81% and smoking in 90% of patients. Abdominal pain was the leading symptom (71%), followed by weight loss, nausea and vomiting, jaundice, and diarrhoea. In 23 patients (66%), recurrent acute pancreatitis attacks were noted. Focal duodenal wall thickening was present in 34 patients (97%), cystic lesions in 80%, pancreatic duct dilatation in 54% and common bile duct dilatation in 46%. Endoscopic treatment was performed on nine patients (26%) and five patients (14%) underwent surgery. Complete symptom relief was reported in 12 patients (34%), partial symptom relief in three (9%), there was no improvement in five (14%), data were not available in three (9%) and 12 (34%) patients died before data analysis. Conclusions PDP is a rare form of pancreatitis, most commonly occurring in the 5th or 6th decade of life, with a predominance in males and patients with a history of smoking and high alcohol consumption. Focal thickening and cystic lesions of the duodenal wall are the most common imaging findings, followed by pancreatic duct and common bile duct dilatation. A minority of patients requires surgery.
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- Waldthaler, J, et al.
(författare)
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[Update on diagnostics and therapy of idiopathic Parkinson's disease]
- 2019
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Ingår i: Fortschritte der Neurologie-Psychiatrie. - : Georg Thieme Verlag KG. - 1439-3522 .- 0720-4299. ; 87:8, s. 445-459
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Tidskriftsartikel (refereegranskat)abstract
- In Deutschland leben mindestens 300000 Menschen mit einem idiopathischen Parkinson-Syndrom. Aufgrund des demografischen Wandels ist mit einer stetig steigenden Zahl Betroffener zu rechnen. In diesem Beitrag werden die evidenzbasierte Diagnostik und Therapie des idiopathischen Parkinson-Syndroms dargestellt. Insbesondere soll ein Überblick über die neuen Erkenntnisse und Entwicklungen der letzten Jahre gegeben werden.
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